Q9US08

PR
Gene name
spo3 (SPAC607.10)
Protein name
Sporulation-specific protein 3
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC607.10
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-167 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9US08

Entry ID Method Resolution Chain Position Source
AF-Q9US08-F1 Predicted AlphaFoldDB

13 variants for Q9US08

Variant ID(s) Position Change Description Diseaes Association Provenance
I_2054103_A_T 53 E>D No Jeffares_SNPs
I_2054456_G_A 171 R>K No Jeffares_SNPs
I_2054641_G_T 233 V>F No Jeffares_SNPs
I_2054815_A_G 291 N>D No Jeffares_SNPs
I_2054921_A_G 326 K>R No Jeffares_SNPs
I_2054969_C_T 342 S>L No Jeffares_SNPs
I_2054977_C_T 345 H>Y No Jeffares_SNPs
I_2055197_C_T 418 A>V No Jeffares_SNPs
I_2055284_C_T 447 A>V No Jeffares_SNPs
I_2055533_C_A 530 T>K No Jeffares_SNPs
I_2055773_G_A 610 R>K No Jeffares_SNPs
I_2055941_G_T 666 R>L No Jeffares_SNPs
I_2056514_G_A 857 G>E No Jeffares_SNPs

No associated diseases with Q9US08

No regional properties for Q9US08

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9US08

Functions

Description
EC Number
Subcellular Localization
  • Prospore membrane ; Peripheral membrane protein
  • Associated with forespore membrane
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
prospore membrane The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
prospore membrane leading edge The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
ascospore-type prospore membrane formation The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MGILSVIRIF IYCLIRLFSF NSRKRNSSID ELERGEINAF ACDKQNTPSP NSECRPLTPL
70 80 90 100 110 120
NSPFRRTVEG DTANLQAPSP TACPSFDSAS SIKSSKEDIA CRKLSTERFF YSPNGIDEMK
130 140 150 160 170 180
KQQQFKKIPT VSITEVEPAF IPSNMEQALF SEEPFVIQDD LSHQINLDDN RKFSRIQKNK
190 200 210 220 230 240
LDPLITVNLV PIVNGENCFN FYETQMETNF LSPEFIKKPS MVDHKRDSEI NAVTAVSADG
250 260 270 280 290 300
SFSPLTETLS STISTLSNDS LDGLSSQKNE FTGFNSNSEW IPNDTVDYIC NSDASSVVSN
310 320 330 340 350 360
LSDFEDCFDQ FGVYDKEYEK KIEKTKRNFP KFQSSATYPP FSAHHQARRN NPQGFRNVKK
370 380 390 400 410 420
RFQLFKDDCT ALTDSDFLDA LPFFNARVII ALYVEWRLRV YETMIIKGEE SLKNLQRARD
430 440 450 460 470 480
GPHNKLWLGV FGNKDTIKKL SNYDRRAISN PYVSNHLNFN VRRVKSDTVY IPTILQLLRS
490 500 510 520 530 540
STQLMTEQAF VASSNLKSTK GLRETRLIQK YKVKGDFEYV YAALYYAAFT QESTLKAVTI
550 560 570 580 590 600
DDILSEDELE DWWYLNLRYT SFITPQLCFE FLDKEADSCR DRLTEVKSEP PKAVIYEEPL
610 620 630 640 650 660
NKLSRFSSDR LFTSHELVAI AELISLNEPP LESGKKFYYE EFQKACQKKR DDYRYSPEIE
670 680 690 700 710 720
FKAAFREKFL QSNEKVPFPR PGEIYEKRCD YFSKYACQNI FISKPLKRSG SIYEVFSDGI
730 740 750 760 770 780
GRVIYGSVLD YEATRNNILL HFGFEIHCAP SEEELIEREE AFKDFHNMLS FKYSANEIYE
790 800 810 820 830 840
FCGTHSRAEV HKNEVLKRMA YYLIDENKEI SILRRILSLR IVEPTTSFTR YEYDLWRTFY
850 860 870 880 890 900
PDVLYLNYSK SGRIPTGSPY IMNGQWRKDL CVSTPPMVDI NSALFPHWFK LSASNLFAGA
910 920 930 940 950 960
EHAGLNRQKP DKIDLDLYEP LPENSYLVAA ELRVLRALRH KNPENIPLLE KWEVRALHQL
970 980 990 1000 1010 1020
MAKIRKYYTV PTDYLSLRMD GLQAMLRKRE YMSCYTFNYF DYACLMDHAY RLYEGFNNQV
VNLPPRIM