Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9US07

Entry ID Method Resolution Chain Position Source
AF-Q9US07-F1 Predicted AlphaFoldDB

11 variants for Q9US07

Variant ID(s) Position Change Description Diseaes Association Provenance
I_1707226_A_C 9 Y>D No Jeffares_SNPs
I_1707043_G_A 55 A>V No Jeffares_SNPs
I_1707029_A_G 60 S>P No Jeffares_SNPs
I_1706757_T_A 134 Q>H No Jeffares_SNPs
I_1706433_C_T 202 D>N No Jeffares_SNPs
I_1706228_C_G 248 V>L No Jeffares_SNPs
I_1706042_A_G 310 F>L No Jeffares_SNPs
I_1705622_G_A 450 R>C No Jeffares_SNPs
I_1705253_A_T 573 S>T No Jeffares_SNPs
I_1705242_C_A 576 L>F No Jeffares_SNPs
I_1705160_T_G 604 T>P No Jeffares_SNPs

No associated diseases with Q9US07

No regional properties for Q9US07

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9US07

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
Ino80 complex A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

5 GO annotations of biological process

Name Definition
CENP-A containing chromatin assembly The formation of chromatin containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
chromatin remodeling A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication.
double-strand break repair The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
positive regulation of transcription involved in G1/S transition of mitotic cell cycle Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAPKRKQPYT EEGIDFKFTQ FQIVPPINQK NFYTEYLKRD DQMYIWRDSA GEKDAKETES
70 80 90 100 110 120
ESANGDTKQD DSKKSQVEEE EDGIEESELG EEKDNKTIVL HIGSQNLRIG LASNKTPTTV
130 140 150 160 170 180
PMVIARKMRA PFAQERCLLK DICHVNEDGN VAFDSEFDSN LKLLDSELKS WLKAQKKRSV
190 200 210 220 230 240
PNGTQLVKNY NKISKPETVP PDDDPEKPDW IHFEQDDHVD VICGKEAFLL PLNEYPEYKL
250 260 270 280 290 300
FYPIKSGVFN ESDYASSQQL LADIYEIFKY SITSLLQIPV SQLSQYSVIF IVPDLYDRVY
310 320 330 340 350 360
VEKILDILFF DLHFGKAAIV QESLCTSFGA GMSAACVVDM GAQKTSISCV EEGVVVPNSR
370 380 390 400 410 420
IKINYGGDDI TLLFMKLLMR SHFPYQDIDL KTPYDWSLAN ALKIKYCGLS EATYNVQLNS
430 440 450 460 470 480
FFSRTPDKGT RKFTFKSLDE TMLAPLGFFR PDIFENENKL HDRYTLFPVP VDVYDNQPNN
490 500 510 520 530 540
PESLAQTTLL QISTPISNIK ANGKDDEEKK EESDLVTPSV KFKPPRVVYC GSLAAPEIKN
550 560 570 580 590 600
EKLIYPLDDA INQSIFSACD GNLSDEKAKN LYSSILIVGG AGQFPGFAHL LEERIHSKRA
610 620 630 640 650 660
NIPTISVIPP PRSMDAQFVA WKGACIYNRI RIVSELWIKN SDWKMLGSRV LQYKTLGYFW
TG