Q9URS1
Gene name |
GDH |
Protein name |
NADP-specific glutamate dehydrogenase |
Names |
NADP-GDH, NADP-dependent glutamate dehydrogenase |
Species |
Penicillium chrysogenum (Penicillium notatum) |
KEGG Pathway |
|
EC number |
1.4.1.4: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9URS1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9URS1-F1 | Predicted | AlphaFoldDB |
No variants for Q9URS1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9URS1 | |||||
No associated diseases with Q9URS1
4 regional properties for Q9URS1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, C-terminal | 189 - 458 | IPR006096 |
| domain | Glutamate/phenylalanine/leucine/valine/L-tryptophan dehydrogenase, dimerisation domain | 44 - 172 | IPR006097 |
| active_site | Leu/Phe/Val dehydrogenases active site | 109 - 122 | IPR033524 |
| domain | NAD(P) binding domain of glutamate dehydrogenase | 182 - 459 | IPR033922 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.4.1.4 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| glutamate dehydrogenase (NADP+) activity | Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| cellular amino acid metabolic process | The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMQNLPFEPE | FEQAYKELAS | TLENSTLFQK | KPEYRKALQV | VSVPERVIQF | RVVWEDDKGQ |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VQINRGYRVQ | FNSALGPYKG | GLRFHPTVNL | SILKFLGFEQ | IFKNALTGLN | MGGGKGGSDF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DPKGKTDNEI | RRFCVSFMTE | LCKHIGADTD | VPAGDIGVTG | REVGFMFGQY | KKIRNQWEGV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LTGKGGSWGG | SLIRPEATGY | GVVYYVEHMI | QHASGGKESF | AGKRVAISGS | GNVAQYAALK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VIELGGSVIS | LSDSQGALVL | NGEEGSFTAE | EINTIAEIKV | QRKQIAELAT | QDAFSSKFKY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| IPGARPWTNI | AGRIDVALPS | ATQNEVSGDE | AKALIAAGCK | FIAEGSNMGS | TQEAIDVFEA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HRDANPGAAA | IWYAPGKAAN | AGGVAVSGLE | MAQNSARVNW | SREEVDSRLK | KIMEDCFNNG |
| 430 | 440 | 450 | 460 | ||
| LSTAKEYVTP | AEGVLPSLVA | GSNIAGFTKV | AEAMKEHGDW | W |