Q9UQY9

PR
Gene name
spo4 (SPBC21C3.18)
Protein name
Cell cycle protein kinase spo4
Names
Sporulation-specific protein 4
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPBC21C3.18
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-58 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

200-209 (Activation loop from InterPro)

Target domain

40-403 (Protein kinase domain)

Relief mechanism

Assay

253-266 (Activation loop from InterPro)

Target domain

40-403 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q9UQY9

Entry ID Method Resolution Chain Position Source
AF-Q9UQY9-F1 Predicted AlphaFoldDB

No variants for Q9UQY9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9UQY9

No associated diseases with Q9UQY9

1 regional properties for Q9UQY9

Type Name Position InterPro Accession
domain Protein kinase domain 40 - 403 IPR000719

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

6 GO annotations of biological process

Name Definition
ascospore-type prospore-specific spindle pole body remodeling A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP).
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
meiosis II The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
peptidyl-serine phosphorylation The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
protein localization to nucleus A process in which a protein transports or maintains the localization of another protein to the nucleus.
signal transduction The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLSMLLPFGN SGVYASDVDR EDRPEIAKLV QAFPTIEEDY HVVKLVGAGS FSSVFKAVDR
70 80 90 100 110 120
HFDSYDNSYW ISSQIEDQMP HDKTKRPKNH FVALKRIYAT VLPSRIQTEL EMLHELRGSD
130 140 150 160 170 180
CVLNMITAVR HQDQVLIVLP FIQHAEFRDF YMKYSLPEIG AYLRDLLKGL AHIDAKGIIH
190 200 210 220 230 240
RDIKPGNFAW NPYTQRGVIL DFGLAQWQEA DAPTENCCVD KLRKLKQEGK YYDYFPFEKT
250 260 270 280 290 300
IADPPEGYLL HDPRPTKRAD RAGTRGFRAP EVLFRCQNQT SSIDVWSVGV ILLCFLTHRY
310 320 330 340 350 360
PFFRCEDDID AIVELAHIFG RNGMSNCALL HGQIWSDNIP TLLDQKHNWL DLIASITKND
370 380 390 400 410 420
ENLILETSSD YQVALAIDLL DKLLELHPSK RVKAKTALQH EFFNACGVTR SGFEAENPFR
SDFPSTVEQ