Q9UA35

PR
Gene name
SLC28A3 (CNT3)
Protein name
Solute carrier family 28 member 3
Names
Concentrative Na(+)-nucleoside cotransporter 3, hfCNT
Species
Eptatretus stoutii (Pacific hagfish)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

8-98 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9UA35

Entry ID Method Resolution Chain Position Source
AF-Q9UA35-F1 Predicted AlphaFoldDB

No variants for Q9UA35

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9UA35

No associated diseases with Q9UA35

3 regional properties for Q9UA35

Type Name Position InterPro Accession
domain Concentrative nucleoside transporter N-terminal domain 200 - 272 IPR002668
domain Nucleoside transporter/FeoB GTPase, Gate domain 282 - 376 IPR011642
domain Concentrative nucleoside transporter C-terminal domain 383 - 605 IPR011657

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of plasma membrane The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

2 GO annotations of molecular function

Name Definition
nucleoside transmembrane transporter activity Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.
symporter activity Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSAFKARGVE NPSYEDPDEK QKPDLEMSKT NGIGVDNPSY YKNPEKYLGN ENEEGKSNND
70 80 90 100 110 120
NEEEEEGEED QGAVERCVNK FYGGIHNFYK RNKKIIHYTF LGLLLVGYFA LVIAACIVNF
130 140 150 160 170 180
KQSLALLVLT LIAIFFFFWD LFIAKYGDKI AEALKPCQKF LDNHWSIIRW FVYGALLLAV
190 200 210 220 230 240
ILWLTLDTAK RGANQVIPFF GLILYILLVF IFSKHPTKVR WRIVIWGLLL QFIFGLIILR
250 260 270 280 290 300
TKPGLDAFNW LGIQVQTFLK YTDAGSRFLF GDDFQDHFFA FAVLPIVIFF STVMSMMYYL
310 320 330 340 350 360
GLMQWLILKV GWLMQITMGT SPMESMVSAG NIFVGQTESP LLIRPYLADL TISEMHSVMS
370 380 390 400 410 420
SGFATIAGSV LGAYISLGIP AAHLLTASVM SAPAALAISK TFWPETKKSK NSTQTSIKLE
430 440 450 460 470 480
KGQENNLVEA ASQGASAAVP LVANIAANLI AFLAVLAFIN ATLSWLGSMF NYPQFSFEII
490 500 510 520 530 540
CSYVLMPFAF MMGVNYDDSF LVAELLGMKT FFNEFVAYQR LSEYIHNRES GGPLFVDGVR
550 560 570 580 590 600
QYMSVRSEAI ATYALCGFAN FGSLGIMIGG LSSLAPHRKS DIASCGIRAL IAGTIACFST
610 620 630 640 650 660
ACIAGVLYIP ELYCPNLLMS TLFENGTTVN TTNLMSCCTD LFKSTTMLTP KNITFTEGFN
670 680
TTMLNGCCTF FPSGFNCSEV RPE