Q9SXB6
Gene name |
MLO2 (At1g11310, T28P6.4) |
Protein name |
MLO-like protein 2 |
Names |
AtMlo2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G11310 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SXB6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SXB6-F1 | Predicted | AlphaFoldDB |
8 variants for Q9SXB6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH04557209 | 34 | H>Q | No | 1000Genomes | |
| ENSVATH04557202 | 86 | Q>H | No | 1000Genomes | |
| tmp_1_3803221_T_C | 116 | D>G | No | 1000Genomes | |
| ENSVATH13879232 | 124 | L>V | No | 1000Genomes | |
| ENSVATH04557201 | 133 | I>S | No | 1000Genomes | |
| tmp_1_3802122_C_T | 312 | G>E | No | 1000Genomes | |
| ENSVATH13879229 | 467 | T>A | No | 1000Genomes | |
| tmp_1_3801084_G_C | 513 | P>A | No | 1000Genomes |
No associated diseases with Q9SXB6
No regional properties for Q9SXB6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9SXB6 | |||
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
| Golgi apparatus | A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plasmodesma | A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| calmodulin binding | Binding to calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to fungus | Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. |
| negative regulation of defense response | Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. |
| response to fungus | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. |
9 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q0DC45 | MLO1 | MLO protein homolog 1 | Oryza sativa subsp japonica (Rice) | PR |
| O80961 | MLO12 | MLO-like protein 12 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB7 | MLO6 | MLO-like protein 6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O23693 | MLO4 | MLO-like protein 4 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9FI00 | MLO11 | MLO-like protein 11 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB1 | MLO14 | MLO-like protein 14 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O80580 | MLO15 | MLO-like protein 15 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O49621 | MLO1 | MLO-like protein 1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q94KB2 | MLO13 | MLO-like protein 13 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MADQVKERTL | EETSTWAVAV | VCFVLLFISI | VLEHSIHKIG | TWFKKKHKQA | LFEALEKVKA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ELMLLGFISL | LLTIGQTPIS | NICISQKVAS | TMHPCSAAEE | AKKYGKKDAG | KKDDGDGDKP |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GRRLLLELAE | SYIHRRSLAT | KGYDKCAEKG | KVAFVSAYGI | HQLHIFIFVL | AVVHVVYCIV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| TYAFGKIKMR | TWKSWEEETK | TIEYQYSNDP | ERFRFARDTS | FGRRHLNFWS | KTRVTLWIVC |
| 250 | 260 | 270 | 280 | 290 | 300 |
| FFRQFFGSVT | KVDYLALRHG | FIMAHFAPGN | ESRFDFRKYI | QRSLEKDFKT | VVEISPVIWF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VAVLFLLTNS | YGLRSYLWLP | FIPLVVILIV | GTKLEVIITK | LGLRIQEKGD | VVRGAPVVQP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GDDLFWFGKP | RFILFLIHLV | LFTNAFQLAF | FAWSTYEFNL | NNCFHESTAD | VVIRLVVGAV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VQILCSYVTL | PLYALVTQMG | SKMKPTVFND | RVATALKKWH | HTAKNETKHG | RHSGSNTPFS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| SRPTTPTHGS | SPIHLLHNFN | NRSVENYPSS | PSPRYSGHGH | HEHQFWDPES | QHQEAETSTH |
| 550 | 560 | 570 | |||
| HSLAHESSEP | VLASVELPPI | RTSKSLRDFS | FKK |