Q9SR43

PR
Gene name
HY2
Protein name
Phytochromobilin:ferredoxin oxidoreductase, chloroplastic
Names
PFB synthase, PPhiB synthase, Phytochromobilin synthase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G09150
EC number
1.3.7.4: With an iron-sulfur protein as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

35-116 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SR43

Entry ID Method Resolution Chain Position Source
AF-Q9SR43-F1 Predicted AlphaFoldDB

23 variants for Q9SR43

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH05796307 8 G>R No 1000Genomes
tmp_3_2803699_G_C 12 G>A No 1000Genomes
tmp_3_2803717_C_T 18 P>L No 1000Genomes
ENSVATH10560565 22 V>I No 1000Genomes
ENSVATH10560566 27 S>N No 1000Genomes
ENSVATH10560567 27 S>R No 1000Genomes
ENSVATH02124683 39 K>N No 1000Genomes
tmp_3_2803786_G_A 41 R>K No 1000Genomes
tmp_3_2803788_T_C 42 F>L No 1000Genomes
ENSVATH02124684 49 V>M No 1000Genomes
tmp_3_2803831_A_G 56 E>G No 1000Genomes
ENSVATH02124685 63 R>K No 1000Genomes
tmp_3_2804077_A_T 77 Y>F No 1000Genomes
ENSVATH10560570 122 E>K No 1000Genomes
tmp_3_2804300_A_C 124 E>A No 1000Genomes
tmp_3_2804341_A_G 138 T>A No 1000Genomes
ENSVATH10560574 166 K>N No 1000Genomes
tmp_3_2804724_A_T 208 H>L No 1000Genomes
ENSVATH13887342 209 K>M No 1000Genomes
ENSVATH13887343 223 L>V No 1000Genomes
ENSVATH10560585 236 S>F No 1000Genomes
ENSVATH10560586 277 D>N No 1000Genomes
ENSVATH10560587 285 E>K No 1000Genomes

No associated diseases with Q9SR43

No regional properties for Q9SR43

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SR43

Functions

Description
EC Number 1.3.7.4 With an iron-sulfur protein as acceptor
Subcellular Localization
  • Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

2 GO annotations of molecular function

Name Definition
cobalt ion binding Binding to a cobalt ion (Co).
phytochromobilin:ferredoxin oxidoreductase activity Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.

2 GO annotations of biological process

Name Definition
chloroplast-nucleus signaling pathway The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.
phytochromobilin biosynthetic process The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MALSMEFGFS IGSCFKAPNP PVLISASPNK INFTLRRRKK RFLLRVSAVS YKEFAESALE
70 80 90 100 110 120
ETRKRIVLEP SHLQEKYSSM TGLDGKTELQ MLAFKSSKIR LLRSMAIENE TMQVFDFAGF
130 140 150 160 170 180
MEPEYDTPIF CANFFTSTNV NIVVLDLNPL HQLTDQTDYQ DKYYNKIMSI YHKYAETFPW
190 200 210 220 230 240
GGKLTGESIK FFSPLVMWTR FSSSKEKHKA LFSAFLEYYQ AWLEMTIQVR EEMEPSHVRA
250 260 270 280 290 300
NCEAQHKYLT WRAQKDPGHG LLKRLVGEAK AKELLRDFLF NGVDELGTKT FIDYFPEYQT
310 320
EDGTVSDKRS IIGKSYETRP WDLTGQFIG