Q9SQ70

PR
Gene name
COR1.1
Protein name
NADPH-dependent codeinone reductase 1-1
Names
Species
Papaver somniferum (Opium poppy)
KEGG Pathway
ag:AAF13736
EC number
1.1.1.247: With NAD(+) or NADP(+) as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

260-321 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SQ70

Entry ID Method Resolution Chain Position Source
AF-Q9SQ70-F1 Predicted AlphaFoldDB

No variants for Q9SQ70

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9SQ70

No associated diseases with Q9SQ70

4 regional properties for Q9SQ70

Type Name Position InterPro Accession
conserved_site Aldo/keto reductase, conserved site 46 - 63 IPR018170-1
conserved_site Aldo/keto reductase, conserved site 150 - 167 IPR018170-2
conserved_site Aldo/keto reductase, conserved site 261 - 276 IPR018170-3
domain NADP-dependent oxidoreductase domain 20 - 292 IPR023210

Functions

Description
EC Number 1.1.1.247 With NAD(+) or NADP(+) as acceptor
Subcellular Localization
  • Cytoplasm, cytosol
  • Present in the cytosolic part of laticifer cells that secrete latex (PubMed:11079569)
  • Localized to the parietal region of the sieve element cytoplasm (PubMed:14508000)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
codeinone reductase (NADPH) activity Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
alkaloid metabolic process The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MESNGVPMIT LSSGIRMPAL GMGTAETMVK GTEREKLAFL KAIEVGYRHF DTAAAYQTEE
70 80 90 100 110 120
CLGEAIAEAL QLGLIKSRDE LFITSKLWCA DAHADLVLPA LQNSLRNLKL DYLDLYLIHH
130 140 150 160 170 180
PVSLKPGKFV NEIPKDHILP MDYKSVWAAM EECQTLGFTR AIGVCNFSCK RLQELMETAN
190 200 210 220 230 240
SPPVVNQVEM SPTLHQKNLR EYCKANNIMI TAHSVLGAVG AAWGTNAVMH SKVLHQIAVA
250 260 270 280 290 300
RGKSVAQVSM RWVYQQGASL VVKSFNEARM KENLKIFDWE LTAEDMEKIS EIPQSRTSSA
310 320
AFLLSPTGPF KTEEEFWDEK D