Q9SKN2
Gene name |
DRB2 (At2g28380, T1B3.10) |
Protein name |
Double-stranded RNA-binding protein 2 |
Names |
dsRNA-binding protein 2, AtDRB2 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G28380 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SKN2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SKN2-F1 | Predicted | AlphaFoldDB |
33 variants for Q9SKN2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_2_12135118_G_T | 134 | P>Q | No | 1000Genomes | |
| tmp_2_12134846_C_T | 186 | R>H | No | 1000Genomes | |
| ENSVATH14564085 | 193 | T>I | No | 1000Genomes | |
| tmp_2_12134807_G_C | 199 | A>G | No | 1000Genomes | |
| ENSVATH05612929 | 204 | A>T | No | 1000Genomes | |
| tmp_2_12134669_G_A | 245 | A>V | No | 1000Genomes | |
| tmp_2_12134602_C_A | 267 | Q>H | No | 1000Genomes | |
| tmp_2_12134592_C_G | 271 | A>P | No | 1000Genomes | |
| tmp_2_12134589_T_G | 272 | N>H | No | 1000Genomes | |
| ENSVATH13447713 | 277 | P>S | No | 1000Genomes | |
| tmp_2_12134485_C_T | 306 | M>I | No | 1000Genomes | |
| tmp_2_12134464_G_T | 313 | N>K | No | 1000Genomes | |
| tmp_2_12134397_C_G | 336 | A>P | No | 1000Genomes | |
| ENSVATH05612924 | 353 | P>L | No | 1000Genomes | |
| ENSVATH05612924 | 353 | P>Q | No | 1000Genomes | |
| ENSVATH14564073 | 359 | A>T | No | 1000Genomes | |
| tmp_2_12134320_C_A | 361 | K>N | No | 1000Genomes | |
| ENSVATH05612922 | 368 | E>D | No | 1000Genomes | |
| tmp_2_12134294_C_A | 370 | R>L | No | 1000Genomes | |
| ENSVATH05612921 | 371 | I>T | No | 1000Genomes | |
| ENSVATH13447711 | 372 | S>L | No | 1000Genomes | |
| tmp_2_12134282_A_T | 374 | V>D | No | 1000Genomes | |
| ENSVATH15164813 | 394 | S>N | No | 1000Genomes | |
| tmp_2_12134192_G_A | 404 | T>I | No | 1000Genomes | |
| tmp_2_12134189_G_A | 405 | A>V | No | 1000Genomes | |
| ENSVATH00252322 | 406 | S>A | No | 1000Genomes | |
| ENSVATH00252321 | 418 | S>L | No | 1000Genomes | |
| tmp_2_12134141_T_A | 421 | E>V | No | 1000Genomes | |
| tmp_2_12134138_G_A | 422 | P>L | No | 1000Genomes | |
| ENSVATH01914179 | 422 | P>S | No | 1000Genomes | |
| ENSVATH13447710 | 424 | T>I | No | 1000Genomes | |
| ENSVATH05612919 | 428 | R>Q | No | 1000Genomes | |
| tmp_2_12134114_T_C | 430 | E>G | No | 1000Genomes |
No associated diseases with Q9SKN2
1 regional properties for Q9SKN2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Short-chain dehydrogenase/reductase, conserved site | 165 - 193 | IPR020904 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| double-stranded RNA binding | Binding to double-stranded RNA. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| miRNA processing | A process leading to the generation of a functional miRNA. Includes the cleavage of stem-loop RNA precursors into microRNAs (miRNAs). miRNAs are a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein, or by increasing the degradation of non-protein-coding RNA transcripts. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MYKNQLQELA | QRSCFNLPSY | TCIREGPDHA | PRFKATVNFN | GEIFESPQYC | STLRQAEHSA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AEVALNALSN | RGPSHSLAAR | ILDETGVYKN | LLQEIAQRVG | APLPRYTTFR | SGLGHQPVFT |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GTVELAGITF | TGDPAKNKKQ | AEKNAAMAAW | SSLKQLAKET | SSSMPEPENI | DELEQVIIAR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ALINYRIKEN | IGTGSSSSAP | VPFAKKFFMQ | NLRPTSPQPS | PATTSRILPF | ICPKQPSRSS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| RSSLAATSGI | DRIMAAALES | RSYQRPQQRF | ANPPYVPMRQ | FRSQCHGMAP | PVTIRTAVPV |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FSAPPMPPPP | CTNNTQLPSS | VYVPSLMRTA | PPVRIAPPVT | IRTAVPVFAS | APPVRIRTAV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| KPTVEAGETR | ISSVQEKESI | PVLPDSLEIG | VEGSTITITD | CEKTASKETE | RAEFKDSSKG |
| 430 | |||||
| EPETARERLE | NLKI |