Q9SKK8
PR
Gene name |
ATL22 (At2g25410, F13B15.7) |
Protein name |
RING-H2 finger protein ATL22 |
Names |
RING-type E3 ubiquitin transferase ATL22 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G25410 |
EC number |
2.3.2.27: Aminoacyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SKK8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SKK8-F1 | Predicted | AlphaFoldDB |
126 variants for Q9SKK8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH01893352 | 5 | L>Q | No | 1000Genomes | |
| ENSVATH05588656 | 6 | L>F | No | 1000Genomes | |
| tmp_2_10814494_C_T | 9 | L>F | No | 1000Genomes | |
| ENSVATH01893353 | 10 | L>F | No | 1000Genomes | |
| ENSVATH01893354 | 11 | N>H | No | 1000Genomes | |
| ENSVATH14551074 | 17 | F>L | No | 1000Genomes | |
| ENSVATH05588657 | 19 | P>L | No | 1000Genomes | |
| ENSVATH14551085 | 20 | L>F | No | 1000Genomes | |
| tmp_2_10814534_A_G | 22 | N>S | No | 1000Genomes | |
| ENSVATH05588659 | 24 | S>F | No | 1000Genomes | |
| ENSVATH01893357 | 26 | Q>* | No | 1000Genomes | |
| ENSVATH01893358 | 26 | Q>P | No | 1000Genomes | |
| tmp_2_10814552_C_T | 28 | P>L | No | 1000Genomes | |
| ENSVATH14551087 | 31 | S>C | No | 1000Genomes | |
| tmp_2_10814561_G_A | 31 | S>N | No | 1000Genomes | |
| ENSVATH13398791 | 34 | C>Y | No | 1000Genomes | |
| ENSVATH01893360 | 37 | E>* | No | 1000Genomes | |
| ENSVATH01893361 | 37 | E>G | No | 1000Genomes | |
| tmp_2_10814584_G_A | 39 | V>I | No | 1000Genomes | |
| ENSVATH00246729 | 41 | A>V | No | 1000Genomes | |
| ENSVATH13398792 | 44 | P>S | No | 1000Genomes | |
| ENSVATH05588660 | 49 | S>P | No | 1000Genomes | |
| ENSVATH05588661 | 52 | P>L | No | 1000Genomes | |
| ENSVATH14551088 | 55 | C>Y | No | 1000Genomes | |
| tmp_2_10814644_G_A | 59 | G>R | No | 1000Genomes | |
| tmp_2_10814653_C_T | 62 | L>F | No | 1000Genomes | |
| ENSVATH01893366 | 63 | I>L | No | 1000Genomes | |
| ENSVATH00246732 | 65 | K>T | No | 1000Genomes | |
| ENSVATH01893367 | 67 | D>G | No | 1000Genomes | |
| ENSVATH13398794 | 67 | D>N | No | 1000Genomes | |
| ENSVATH05588662 | 68 | A>V | No | 1000Genomes | |
| ENSVATH00246733 | 71 | T>A | No | 1000Genomes | |
| ENSVATH01893368 | 73 | K>M | No | 1000Genomes | |
| tmp_2_10814686_A_C | 73 | K>Q | No | 1000Genomes | |
| ENSVATH05588663 | 75 | P>L | No | 1000Genomes | |
| ENSVATH00246734 | 77 | S>T | No | 1000Genomes | |
| ENSVATH05588664 | 78 | E>K | No | 1000Genomes | |
| ENSVATH00246735 | 81 | L>V | No | 1000Genomes | |
| ENSVATH01893370 | 83 | K>R | No | 1000Genomes | |
| ENSVATH05588666 | 88 | E>K | No | 1000Genomes | |
| tmp_2_10814734_A_T | 89 | T>S | No | 1000Genomes | |
| ENSVATH13398809 | 91 | R>H | No | 1000Genomes | |
| ENSVATH13398810 | 93 | R>C | No | 1000Genomes | |
| ENSVATH13398811 | 96 | D>N | No | 1000Genomes | |
| ENSVATH05588668 | 97 | P>T | No | 1000Genomes | |
| tmp_2_10814761_G_A | 98 | E>K | No | 1000Genomes | |
| tmp_2_10814774_C_T | 102 | A>V | No | 1000Genomes | |
| ENSVATH01893376 | 103 | R>K | No | 1000Genomes | |
| tmp_2_10814788_A_G | 107 | N>D | No | 1000Genomes | |
| tmp_2_10814794_G_C | 109 | D>H | No | 1000Genomes | |
| tmp_2_10814798_C_G | 110 | P>R | No | 1000Genomes | |
| tmp_2_10814801_C_T | 111 | S>L | No | 1000Genomes | |
| ENSVATH05588671 | 112 | G>R | No | 1000Genomes | |
| ENSVATH05588672 | 114 | P>H | No | 1000Genomes | |
| ENSVATH05588672 | 114 | P>L | No | 1000Genomes | |
| ENSVATH01893378 | 114 | P>S | No | 1000Genomes | |
| ENSVATH01893379 | 117 | F>L | No | 1000Genomes | |
| ENSVATH01893380 | 117 | F>S | No | 1000Genomes | |
| ENSVATH05588673 | 118 | L>F | No | 1000Genomes | |
| ENSVATH05588674 | 119 | R>C | No | 1000Genomes | |
| ENSVATH05588675 | 119 | R>P | No | 1000Genomes | |
| tmp_2_10814847_G_T | 126 | L>F | No | 1000Genomes | |
| ENSVATH00246738 | 129 | P>H | No | 1000Genomes | |
| ENSVATH00246739 | 131 | E>V | No | 1000Genomes | |
| tmp_2_10814863_G_T | 132 | A>S | No | 1000Genomes | |
| ENSVATH01893384 | 134 | I>V | No | 1000Genomes | |
| ENSVATH13398812 | 135 | T>I | No | 1000Genomes | |
| ENSVATH13398812 | 135 | T>N | No | 1000Genomes | |
| tmp_2_10814875_G_T | 136 | A>S | No | 1000Genomes | |
| ENSVATH01893385 | 142 | D>N | No | 1000Genomes | |
| ENSVATH05588677 | 144 | L>I | No | 1000Genomes | |
| ENSVATH05588678 | 145 | G>D | No | 1000Genomes | |
| ENSVATH00246742 | 147 | T>S | No | 1000Genomes | |
| ENSVATH05588680 | 155 | Q>H | No | 1000Genomes | |
| ENSVATH00246744 | 160 | G>V | No | 1000Genomes | |
| ENSVATH05588681 | 161 | S>L | No | 1000Genomes | |
| tmp_2_10814957_C_T | 163 | P>L | No | 1000Genomes | |
| ENSVATH01893386 | 171 | I>T | No | 1000Genomes | |
| tmp_2_10814998_T_C | 177 | S>P | No | 1000Genomes | |
| ENSVATH00246746 | 179 | F>Y | No | 1000Genomes | |
| ENSVATH13398813 | 183 | T>A | No | 1000Genomes | |
| tmp_2_10815017_C_T | 183 | T>M | No | 1000Genomes | |
| ENSVATH01893387 | 184 | T>A | No | 1000Genomes | |
| ENSVATH01893388 | 185 | Y>F | No | 1000Genomes | |
| ENSVATH01893389 | 187 | D>G | No | 1000Genomes | |
| tmp_2_10815032_G_A | 188 | G>D | No | 1000Genomes | |
| tmp_2_10815038_A_G | 190 | N>S | No | 1000Genomes | |
| tmp_2_10815043_C_T | 192 | R>* | No | 1000Genomes | |
| tmp_2_10815044_G_A | 192 | R>Q | No | 1000Genomes | |
| ENSVATH01893390 | 194 | M>L | No | 1000Genomes | |
| tmp_2_10815068_C_T | 200 | S>L | No | 1000Genomes | |
| tmp_2_10815071_C_T | 201 | P>L | No | 1000Genomes | |
| ENSVATH05588682 | 204 | R>K | No | 1000Genomes | |
| tmp_2_10815095_G_A,T | 209 | R>I | No | 1000Genomes | |
| tmp_2_10815095_G_A,T | 209 | R>K | No | 1000Genomes | |
| tmp_2_10815097_A_G | 210 | T>A | No | 1000Genomes | |
| tmp_2_10815098_C_T | 210 | T>I | No | 1000Genomes | |
| ENSVATH05588683 | 225 | E>K | No | 1000Genomes | |
| tmp_2_10815155_C_A | 229 | S>Y | No | 1000Genomes | |
| ENSVATH13398845 | 230 | V>A | No | 1000Genomes | |
| tmp_2_10815157_G_A | 230 | V>I | No | 1000Genomes | |
| tmp_2_10815161_A_G | 231 | N>S | No | 1000Genomes | |
| ENSVATH13398846 | 232 | P>L | No | 1000Genomes | |
| tmp_2_10815163_C_T | 232 | P>S | No | 1000Genomes | |
| ENSVATH05588684 | 233 | G>R | No | 1000Genomes | |
| ENSVATH00246755 | 245 | M>I | No | 1000Genomes | |
| ENSVATH01893405 | 256 | L>M | No | 1000Genomes | |
| tmp_2_10815570_G_C | 263 | V>L | No | 1000Genomes | |
| ENSVATH05588694 | 269 | R>S | No | 1000Genomes | |
| ENSVATH13398870 | 273 | Q>H | No | 1000Genomes | |
| ENSVATH01893406 | 276 | Q>H | No | 1000Genomes | |
| tmp_2_10815615_G_A | 278 | V>M | No | 1000Genomes | |
| tmp_2_10815621_G_A | 280 | A>T | No | 1000Genomes | |
| tmp_2_10815651_C_T | 290 | P>S | No | 1000Genomes | |
| tmp_2_10815658_A_T | 292 | N>I | No | 1000Genomes | |
| tmp_2_10815664_T_G | 294 | V>G | No | 1000Genomes | |
| ENSVATH00246756 | 297 | I>M | No | 1000Genomes | |
| tmp_2_10815681_G_A | 300 | D>N | No | 1000Genomes | |
| ENSVATH01893407 | 309 | K>R | No | 1000Genomes | |
| tmp_2_10815753_G_A | 324 | D>N | No | 1000Genomes | |
| ENSVATH05588695 | 336 | T>I | No | 1000Genomes | |
| tmp_2_10815825_C_A | 348 | H>N | No | 1000Genomes | |
| tmp_2_10815832_T_A | 350 | F>Y | No | 1000Genomes | |
| tmp_2_10815834_C_G | 351 | H>D | No | 1000Genomes | |
| tmp_2_10815891_A_G | 370 | S>G | No | 1000Genomes | |
| tmp_2_10815915_T_C | 378 | D>R | No | 1000Genomes |
No associated diseases with Q9SKK8
Functions
| Description | ||
|---|---|---|
| EC Number | 2.3.2.27 | Aminoacyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| polysaccharide binding | Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. |
| transferase activity | Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein ubiquitination | The process in which one or more ubiquitin groups are added to a protein. |
17 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9VE61 | CG7694 | E3 ubiquitin-protein ligase RNF181 homolog | Drosophila melanogaster (Fruit fly) | PR |
| O00237 | RNF103 | E3 ubiquitin-protein ligase RNF103 | Homo sapiens (Human) | PR |
| Q86Y13 | DZIP3 | E3 ubiquitin-protein ligase DZIP3 | Homo sapiens (Human) | PR |
| Q9Y3E7 | CHMP3 | Charged multivesicular body protein 3 | Homo sapiens (Human) | EV |
| Q9R1W3 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Mus musculus (Mouse) | PR |
| Q9EPZ8 | Rnf103 | E3 ubiquitin-protein ligase RNF103 | Rattus norvegicus (Rat) | PR |
| Q9SI09 | XERICO | Probable E3 ubiquitin-protein ligase XERICO | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9ZV51 | ATL56 | RING-H2 finger protein ATL56 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O22255 | ATL64 | RING-H2 finger protein ATL64 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8RXX9 | ATL6 | E3 ubiquitin-protein ligase ATL6 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GYT9 | SIS3 | E3 ubiquitin-protein ligase SIS3 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LZJ6 | ATL5 | RING-H2 finger protein ATL5 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8GXF8 | SGR9 | E3 ubiquitin-protein ligase SGR9, amyloplastic | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q8LGA5 | ATL31 | E3 ubiquitin-protein ligase ATL31 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LUZ9 | ATL63 | RING-H2 finger protein ATL63 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH01 | ATL21A | Putative RING-H2 finger protein ATL21A | Arabidopsis thaliana (Mouse-ear cress) | PR |
| P0CH02 | ATL21B | Putative RING-H2 finger protein ATL21B | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTSKLLPLLL | NLIFLFFFPL | LNASEQKPCY | SFSCSQESVV | ARFPFSLFSY | QPESCGYSGF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NLICKDDANT | TLKLPKSEPF | LVKEIDYETQ | RIRLNDPENC | LARRLLNFDP | SGSPFSFLRS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RNYTFLICPK | EANITASFRA | IDCLGNTTSS | FFVVQFENLG | SMPSSCHIFK | ILPLPFSWFV |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AYTTYPDGQN | SRDMWLKWDS | PDCRDCERRT | NSRCGFKNNT | SHQVECFSSV | NPGLHNTGLQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VLKIMCLSLV | GPLTALTFCV | GLVMCSSERV | SSQIQQAVVA | RLSGSVTSQP | SNEVARIGLD |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ESTIESYKKV | ELGESRRLPT | GSNDVVCPIC | LSEYATKETV | RCLPECEHCF | HTECIDAWLK |
| 370 | |||||
| LHSSCPVCRS | NPSPLRD |