Q9SIF3
Gene name |
At2g04020 (F3C11.13) |
Protein name |
GDSL esterase/lipase At2g04020 |
Names |
Extracellular lipase At2g04020 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT2G04020 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SIF3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SIF3-F1 | Predicted | AlphaFoldDB |
53 variants for Q9SIF3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH10914067 | 3 | L>F | No | 1000Genomes | |
| tmp_2_1274437_C_G | 4 | P>R | No | 1000Genomes | |
| ENSVATH01633565 | 4 | P>S | No | 1000Genomes | |
| ENSVATH00205244 | 8 | E>D | No | 1000Genomes | |
| tmp_2_1274451_T_C | 9 | S>P | No | 1000Genomes | |
| tmp_2_1274467_T_C | 14 | I>T | No | 1000Genomes | |
| tmp_2_1274469_C_A | 15 | L>I | No | 1000Genomes | |
| tmp_2_1274470_T_C | 15 | L>P | No | 1000Genomes | |
| tmp_2_1274475_T_G | 17 | S>A | No | 1000Genomes | |
| ENSVATH05237089 | 18 | F>Y | No | 1000Genomes | |
| ENSVATH05237090 | 28 | K>T | No | 1000Genomes | |
| tmp_2_1274527_C_T | 34 | A>V | No | 1000Genomes | |
| ENSVATH01633566 | 39 | G>E | No | 1000Genomes | |
| ENSVATH05237091 | 45 | Y>* | No | 1000Genomes | |
| tmp_2_1274586_C_T | 54 | P>S | No | 1000Genomes | |
| tmp_2_1274604_C_T | 60 | L>F | No | 1000Genomes | |
| tmp_2_1274608_C_G | 61 | P>R | No | 1000Genomes | |
| tmp_2_1274629_A_T | 68 | Y>F | No | 1000Genomes | |
| tmp_2_1274646_G_A | 74 | D>N | No | 1000Genomes | |
| tmp_2_1274665_C_A | 80 | A>D | No | 1000Genomes | |
| tmp_2_1274863_T_C | 96 | I>T | No | 1000Genomes | |
| ENSVATH01633570 | 100 | L>I | No | 1000Genomes | |
| tmp_2_1274910_G_A | 112 | D>N | No | 1000Genomes | |
| ENSVATH10914174 | 117 | I>M | No | 1000Genomes | |
| tmp_2_1274955_G_A | 127 | G>S | No | 1000Genomes | |
| ENSVATH05237101 | 129 | G>V | No | 1000Genomes | |
| ENSVATH10914395 | 136 | K>N | No | 1000Genomes | |
| tmp_2_1274989_C_T | 138 | A>V | No | 1000Genomes | |
| tmp_2_1275067_G_A | 139 | G>E | No | 1000Genomes | |
| tmp_2_1275101_G_T | 150 | L>F | No | 1000Genomes | |
| tmp_2_1275144_A_T | 165 | T>S | No | 1000Genomes | |
| tmp_2_1275166_A_T | 172 | H>L | No | 1000Genomes | |
| tmp_2_1275190_C_T | 180 | T>I | No | 1000Genomes | |
| ENSVATH05237106 | 181 | V>M | No | 1000Genomes | |
| tmp_2_1275213_G_A | 188 | A>T | No | 1000Genomes | |
| ENSVATH05237108 | 189 | F>Y | No | 1000Genomes | |
| ENSVATH05237109 | 201 | A>T | No | 1000Genomes | |
| ENSVATH05237110 | 202 | D>N | No | 1000Genomes | |
| ENSVATH00205247 | 203 | E>K | No | 1000Genomes | |
| ENSVATH04104774 | 210 | K>E | No | 1000Genomes | |
| ENSVATH05237112 | 212 | I>L | No | 1000Genomes | |
| ENSVATH13930561 | 241 | T>M | No | 1000Genomes | |
| ENSVATH01633575 | 253 | R>Q | No | 1000Genomes | |
| ENSVATH01633576 | 254 | Y>H | No | 1000Genomes | |
| tmp_2_1275635_C_T | 256 | S>L | No | 1000Genomes | |
| ENSVATH05237119 | 268 | L>F | No | 1000Genomes | |
| ENSVATH05237120 | 281 | R>W | No | 1000Genomes | |
| ENSVATH10914404 | 288 | P>A | No | 1000Genomes | |
| ENSVATH10914404 | 288 | P>T | No | 1000Genomes | |
| ENSVATH01633579 | 291 | T>N | No | 1000Genomes | |
| ENSVATH10914575 | 297 | P>L | No | 1000Genomes | |
| ENSVATH05237121 | 315 | E>Q | No | 1000Genomes | |
| ENSVATH05237123 | 322 | V>M | No | 1000Genomes |
No associated diseases with Q9SIF3
4 regional properties for Q9SIF3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | F-box domain | 1 - 49 | IPR001810 |
| domain | FBD domain | 374 - 442 | IPR006566 |
| repeat | Leucine-rich repeat 2 | 153 - 179 | IPR013101-1 |
| repeat | Leucine-rich repeat 2 | 452 - 480 | IPR013101-2 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| extracellular region | The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| hydrolase activity, acting on ester bonds | Catalysis of the hydrolysis of any ester bond. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| lipid catabolic process | The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9M2R9 | At3g50400 | GDSL esterase/lipase At3g50400 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGLPSSLESY | LLLILLSFLN | VSTIYSSKPS | KEEAVLFGGN | FPAFYVIGDS | LVDPGNNNHL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PTMIRANYPP | YGSDFEGGKA | TGRFSNGKTI | ADYIAIYYKL | PLVPAYLGLS | DDRKDTISTG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| MNYASAGCGI | RRLTGKIAGK | CLSLSKQVDL | FEETIEKHLK | TNFKTPYELR | EHLAHSLFMT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| VIGVNDYAFF | YTRLTDANDF | ADELLHKFLK | KIEKLHKLGA | RKFFINNIKP | LGCYPNIVAK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TFMLGLRGPS | TNRYSSNLLN | TTGPCCPLDY | DGSLTSSCKR | RSKTCKAPDS | THIFFDPRHP |
| 310 | 320 | ||||
| TQLANFMYSI | ACFDERTICH | VV |