Q9SI87

PR
Gene name
At2g10550 (T4D8.4)
Protein name
Probable inactive uracil-DNA glycosylase, mitochondrial
Names
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT2G10550
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-108 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SI87

Entry ID Method Resolution Chain Position Source
AF-Q9SI87-F1 Predicted AlphaFoldDB

112 variants for Q9SI87

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH12469522 2 A>T No 1000Genomes
tmp_2_4096916_G_A 2 A>V No 1000Genomes
ENSVATH05351187 3 L>S No 1000Genomes
ENSVATH01717947 4 S>L No 1000Genomes
tmp_2_4096911_A_G 4 S>P No 1000Genomes
ENSVATH12469521 6 P>S No 1000Genomes
tmp_2_4096898_G_A 8 T>I No 1000Genomes
tmp_2_4096888_A_T 11 D>E No 1000Genomes
ENSVATH01717946 11 D>N No 1000Genomes
ENSVATH05351183 15 P>L No 1000Genomes
ENSVATH01717945 16 A>P No 1000Genomes
ENSVATH01717945 16 A>T No 1000Genomes
ENSVATH12469520 19 L>H No 1000Genomes
ENSVATH14208872 19 L>I No 1000Genomes
ENSVATH12469520 19 L>P No 1000Genomes
ENSVATH05351182 20 K>Q No 1000Genomes
ENSVATH01717943 21 A>T No 1000Genomes
ENSVATH01717942 21 A>V No 1000Genomes
ENSVATH05351181 23 P>L No 1000Genomes
tmp_2_4096850_G_A 24 S>F No 1000Genomes
tmp_2_4096847_G_A 25 S>F No 1000Genomes
ENSVATH12469519 27 S>Y No 1000Genomes
ENSVATH05351180 28 S>C No 1000Genomes
ENSVATH05351179 29 F>L No 1000Genomes
ENSVATH12469517 30 P>S No 1000Genomes
tmp_2_4096830_CG_TG,C 31 A>T No 1000Genomes
tmp_2_4096829_G_A 31 A>V No 1000Genomes
tmp_2_4096823_G_A 33 S>F No 1000Genomes
ENSVATH05351177 33 S>T No 1000Genomes
ENSVATH01717940 34 V>F No 1000Genomes
ENSVATH01717940 34 V>I No 1000Genomes
ENSVATH01717940 34 V>L No 1000Genomes
ENSVATH05351175 36 G>E No 1000Genomes
ENSVATH05351176 36 G>R No 1000Genomes
ENSVATH12469515 38 S>F No 1000Genomes
ENSVATH14208871 38 S>T No 1000Genomes
ENSVATH12469354 41 L>F No 1000Genomes
ENSVATH12469353 42 G>D No 1000Genomes
ENSVATH05351173 43 S>F No 1000Genomes
ENSVATH05351173 43 S>Y No 1000Genomes
ENSVATH05351171 50 R>P No 1000Genomes
ENSVATH01717939 51 V>E No 1000Genomes
ENSVATH05351170 52 T>I No 1000Genomes
ENSVATH05351169 53 V>I No 1000Genomes
ENSVATH05351168 56 A>T No 1000Genomes
ENSVATH05351167 56 A>V No 1000Genomes
ENSVATH01717938 57 V>F No 1000Genomes
ENSVATH05351166 58 A>D No 1000Genomes
tmp_2_4096749_C_T 58 A>T No 1000Genomes
ENSVATH05351166 58 A>V No 1000Genomes
ENSVATH01717937 59 D>N No 1000Genomes
tmp_2_4096743_C_A 60 D>Y No 1000Genomes
ENSVATH01717936 62 S>F No 1000Genomes
ENSVATH12469350 62 S>P No 1000Genomes
ENSVATH12469350 62 S>T No 1000Genomes
ENSVATH05351164 63 G>C No 1000Genomes
ENSVATH05351164 63 G>S No 1000Genomes
tmp_2_4096719_G_A 68 Q>* No 1000Genomes
ENSVATH01717935 70 A>T No 1000Genomes
ENSVATH05351162 71 R>G No 1000Genomes
tmp_2_4096707_C_A 72 A>S No 1000Genomes
ENSVATH05351161 73 E>K No 1000Genomes
tmp_2_4096698_G_A 75 H>Y No 1000Genomes
ENSVATH05351160 76 K>N No 1000Genomes
ENSVATH05351159 77 F>L No 1000Genomes
tmp_2_4096688_A_C,G 78 V>A No 1000Genomes
tmp_2_4096688_A_C,G 78 V>G No 1000Genomes
ENSVATH05351157 78 V>L No 1000Genomes
tmp_2_4096686_C_T 79 A>T No 1000Genomes
tmp_2_4096685_G_A 79 A>V No 1000Genomes
ENSVATH05351156 81 S>F No 1000Genomes
ENSVATH05351154 86 A>T No 1000Genomes
ENSVATH05351153 86 A>V No 1000Genomes
ENSVATH01717933 88 C>W No 1000Genomes
ENSVATH01717932 90 V>M No 1000Genomes
ENSVATH05351151 93 T>I No 1000Genomes
ENSVATH05351151 93 T>K No 1000Genomes
ENSVATH01717931 95 A>E No 1000Genomes
ENSVATH05351150 95 A>T No 1000Genomes
tmp_2_4096631_C_T 97 G>D No 1000Genomes
ENSVATH05351149 97 G>S No 1000Genomes
ENSVATH05351108 99 I>F No 1000Genomes
ENSVATH05351106 100 L>F No 1000Genomes
ENSVATH05351105 103 D>G No 1000Genomes
ENSVATH12469069 103 D>N No 1000Genomes
ENSVATH12469068 105 V>A No 1000Genomes
ENSVATH01717907 106 K>N No 1000Genomes
ENSVATH01717906 108 W>L No 1000Genomes
ENSVATH05351103 111 P>S No 1000Genomes
ENSVATH05351102 112 S>F No 1000Genomes
ENSVATH05351101 114 C>S No 1000Genomes
tmp_2_4096168_T_C 116 K>E No 1000Genomes
ENSVATH05351099 120 P>S No 1000Genomes
ENSVATH12468973 122 S>C No 1000Genomes
ENSVATH12468973 122 S>G No 1000Genomes
ENSVATH05351094 127 F>L No 1000Genomes
ENSVATH05351093 128 K>T No 1000Genomes
tmp_2_4096129_C_T 129 E>K No 1000Genomes
ENSVATH05351092 129 E>V No 1000Genomes
tmp_2_4096120_T_A 132 K>* No 1000Genomes
tmp_2_4096103_C_CTTAA 137 K>N No 1000Genomes
ENSVATH01717902 140 M>I No 1000Genomes
ENSVATH01717903 140 M>R No 1000Genomes
ENSVATH05351090 140 M>V No 1000Genomes
ENSVATH01717901 142 Y>* No 1000Genomes
tmp_2_4096084_T_C,A 144 R>* No 1000Genomes
tmp_2_4096084_T_C,A 144 R>G No 1000Genomes
ENSVATH14894066 147 K>E No 1000Genomes
ENSVATH07811354 151 V>A No 1000Genomes
ENSVATH12468970 152 S>L No 1000Genomes
tmp_2_4096054_C_T 154 V>M No 1000Genomes
ENSVATH12468965 158 A>V No 1000Genomes

No associated diseases with Q9SI87

No regional properties for Q9SI87

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9SI87

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
uracil DNA N-glycosylase activity Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.

1 GO annotations of biological process

Name Definition
base-excision repair, AP site formation via deaminated base removal A base-excision repair, AP site formation process occurring via excision of a deaminated base.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MALSTPKTLM DFFQPAKRLK ASPSSSSSFP AVSVAGRSRD LGSVANSPPR VTVTTAVADD
70 80 90 100 110 120
SSGLTPEQVA RAEFHKFVAK SKSNLAVCSV KVTKAKGLIL IMDLVKLWVY PSMCLKEKSP
130 140 150 160
SSLLNIFKEL HKDVGDKLHM VYFRRNKKEN VSHVTSLAVE DVTGITRTKG