AiPD: Autoinhibited Protein Database

Gene name	CPEFG (SCO1, At1g62750, F23N19.11)
Protein name	Elongation factor G, chloroplastic
Names	cEF-G, Elongation factor EF-G/SCO1, Protein SNOWY COTYLEDON 1, chloroplastic, AtSCO1
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT1G62750
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-119 (Predicted disordered autoinhibitory region) PR

1-119 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9SI75-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
ENSVATH05040011	3	A>T	No	1000Genomes
tmp_1_23236168_A_G	52	S>P	No	1000Genomes
ENSVATH01443011	56	Q>H	No	1000Genomes
tmp_1_23236140_G_C	61	S>C	No	1000Genomes
ENSVATH05040010	62	R>L	No	1000Genomes
tmp_1_23236129_G_T	65	L>I	No	1000Genomes
ENSVATH13701596	69	K>N	No	1000Genomes
ENSVATH01443009	70	L>F	No	1000Genomes
ENSVATH01443007	72	Q>H	No	1000Genomes
tmp_1_23236107_T_A	72	Q>L	No	1000Genomes
ENSVATH13701595	75	K>N	No	1000Genomes
ENSVATH05039999	87	A>G	No	1000Genomes
ENSVATH05039999	87	A>V	No	1000Genomes
tmp_1_23235865_C_T	90	A>T	No	1000Genomes
tmp_1_23235653_T_G	160	K>N	No	1000Genomes
ENSVATH01442978	182	L>F	No	1000Genomes
tmp_1_23235475_C_T	220	V>I	No	1000Genomes
ENSVATH00114683	266	R>K	No	1000Genomes
ENSVATH05039994	295	Q>K	No	1000Genomes
ENSVATH01442970	320	V>I	No	1000Genomes
tmp_1_23235170_C_G	321	E>D	No	1000Genomes
ENSVATH13701590	369	V>I	No	1000Genomes
ENSVATH13701588	384	I>V	No	1000Genomes
ENSVATH13701583	632	L>I	No	1000Genomes
ENSVATH00114668	695	E>K	No	1000Genomes

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9SI75

		Description
EC Number
Subcellular Localization	Plastid, chloroplast
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
apoplast	The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
chloroplast envelope	The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
chloroplast stroma	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

Name	Definition
ATP binding	Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GTP binding	Binding to GTP, guanosine triphosphate.
GTPase activity	Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
mRNA binding	Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
translation elongation factor activity	Functions in chain elongation during polypeptide synthesis at the ribosome.

Name	Definition
chloroplast organization	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
mitochondrial translation	The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
post-embryonic development	The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
ribosome disassembly	The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
seed germination	The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
I1K0K6	fusA2	Elongation factor G-2, chloroplastic	Glycine max (Soybean) (Glycine hispida)	PR
P34811	fusA1	Elongation factor G-1, chloroplastic	Glycine max (Soybean) (Glycine hispida)	PR