Q9SF91

PR
Gene name
RABE1E (RAB8E, At3g09900, F8A24.5)
Protein name
Ras-related protein RABE1e
Names
AtRABE1e, Ras-related protein Rab8E, AtRab8E
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G09900
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

148-218 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SF91

Entry ID Method Resolution Chain Position Source
AF-Q9SF91-F1 Predicted AlphaFoldDB

17 variants for Q9SF91

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH13890223 3 V>L No 1000Genomes
ENSVATH05800421 38 D>G No 1000Genomes
tmp_3_3035213_T_G 43 S>R No 1000Genomes
ENSVATH05800424 59 L>V No 1000Genomes
tmp_3_3035625_A_T 92 L>F No 1000Genomes
tmp_3_3035623_T_G 92 L>V No 1000Genomes
tmp_3_3035636_A_G 96 D>G No 1000Genomes
ENSVATH13890256 105 N>D No 1000Genomes
tmp_3_3035781_C_A 112 N>K No 1000Genomes
tmp_3_3035845_G_A 134 E>K No 1000Genomes
ENSVATH05800435 140 P>T No 1000Genomes
ENSVATH05800439 184 S>R No 1000Genomes
ENSVATH05800440 185 D>N No 1000Genomes
tmp_3_3036189_A_C 189 E>A No 1000Genomes
ENSVATH00314154 189 E>K No 1000Genomes
tmp_3_3036317_G_T 199 D>Y No 1000Genomes
tmp_3_3036366_G_C 215 C>S No 1000Genomes

No associated diseases with Q9SF91

1 regional properties for Q9SF91

Type Name Position InterPro Accession
domain Small GTP-binding protein domain 7 - 162 IPR005225

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane
  • Cell membrane ; Lipid-anchor
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
intracellular membrane-bounded organelle Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.

3 GO annotations of biological process

Name Definition
protein secretion The controlled release of proteins from a cell.
regulation of exocytosis Any process that modulates the frequency, rate or extent of exocytosis.
vesicle docking involved in exocytosis The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.

29 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
P07560 SEC4 Ras-related protein SEC4 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) PR
Q1RMR4 RAB15 Ras-related protein Rab-15 Bos taurus (Bovine) PR
Q2HJI8 RAB8B Ras-related protein Rab-8B Bos taurus (Bovine) PR
A4FV54 RAB8A Ras-related protein Rab-8A Bos taurus (Bovine) PR
Q5F470 RAB8A Ras-related protein Rab-8A Gallus gallus (Chicken) PR
P61007 RAB8A Ras-related protein Rab-8A Canis lupus familiaris (Dog) (Canis familiaris) PR
P51152 RAB12 Ras-related protein Rab-12 Canis lupus familiaris (Dog) (Canis familiaris) PR
P0C0E4 RAB40AL Ras-related protein Rab-40A-like Homo sapiens (Human) PR
Q12829 RAB40B Ras-related protein Rab-40B Homo sapiens (Human) PR
Q6IQ22 RAB12 Ras-related protein Rab-12 Homo sapiens (Human) PR
Q8WXH6 RAB40A Ras-related protein Rab-40A Homo sapiens (Human) PR
Q92930 RAB8B Ras-related protein Rab-8B Homo sapiens (Human) PR
Q96S21 RAB40C Ras-related protein Rab-40C Homo sapiens (Human) PR
P61006 RAB8A Ras-related protein Rab-8A Homo sapiens (Human) PR
Q8K386 Rab15 Ras-related protein Rab-15 Mus musculus (Mouse) PR
Q8CB87 Rab44 Ras-related protein Rab-44 Mus musculus (Mouse) PR
P35283 Rab12 Ras-related protein Rab-12 Mus musculus (Mouse) PR
P55258 Rab8a Ras-related protein Rab-8A Mus musculus (Mouse) PR
P61028 Rab8b Ras-related protein Rab-8B Mus musculus (Mouse) PR
Q8VHQ4 Rab40c Ras-related protein Rab-40C Mus musculus (Mouse) PR
Q9DD03 Rab13 Ras-related protein Rab-13 Mus musculus (Mouse) PR
Q8VHP8 Rab40b Ras-related protein Rab-40B Mus musculus (Mouse) PR
P35289 Rab15 Ras-related protein Rab-15 Rattus norvegicus (Rat) PR
P35280 Rab8a Ras-related protein Rab-8A Rattus norvegicus (Rat) PR
P70550 Rab8b Ras-related protein Rab-8B Rattus norvegicus (Rat) PR
P35284 Rab12 Ras-related protein Rab-12 Rattus norvegicus (Rat) PR
P35281 Rab10 Ras-related protein Rab-10 Rattus norvegicus (Rat) PR
O24466 RABE1A Ras-related protein RABE1a Arabidopsis thaliana (Mouse-ear cress) PR
Q9LZD4 RABE1D Ras-related protein RABE1d Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAVAPARARS DYDYLIKLLL IGDSGVGKSC LLLRFSDDTF TTSFITTIGI DFKIRTVELD
70 80 90 100 110 120
GKRIKLQIWD TAGQERFRTI TTAYYRGAMG ILLVYDVTDE SSFNNIRNWM KNIEQHASDS
130 140 150 160 170 180
VNKILVGNKA DMDESKRAVP TSKGQALADE YGIKFFETSA KTNQNVEQVF LSIAKDIKQR
190 200 210
LTESDTKAEP QGIKITKQDA NKASSSSTNE KSACCSYV