Q9SEH7

PR
Gene name
PMT2
Protein name
Putrescine N-methyltransferase 2
Names
NtPMT2
Species
Nicotiana tabacum (Common tobacco)
KEGG Pathway
nta:107799426
EC number
2.1.1.53: Methyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-74 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9SEH7

Entry ID Method Resolution Chain Position Source
AF-Q9SEH7-F1 Predicted AlphaFoldDB

No variants for Q9SEH7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9SEH7

No associated diseases with Q9SEH7

3 regional properties for Q9SEH7

Type Name Position InterPro Accession
conserved_site Polyamine biosynthesis domain, conserved site 143 - 156 IPR030373
domain Polyamine biosynthesis domain 64 - 301 IPR030374
domain Spermidine synthase, tetramerisation domain 65 - 119 IPR035246

Functions

Description
EC Number 2.1.1.53 Methyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
putrescine N-methyltransferase activity Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+).
spermidine synthase activity Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.

5 GO annotations of biological process

Name Definition
methylation The process in which a methyl group is covalently attached to a molecule.
nicotine biosynthetic process The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
polyamine biosynthetic process The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
putrescine biosynthetic process The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.
response to jasmonic acid Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEVISTNTNG STIFKSGAIP MNGHHNGTSK HQNGHKNGTS EQQNGTISLD NGNELLGNSN
70 80 90 100 110 120
CIKPGWFSEF SALWPGEAFS LKVEKLLFQG KSDYQDVMLF ESATYGKVLT LDGAIQHTEN
130 140 150 160 170 180
GGFPYTEMIV HLPLGSIPNP KKVLIIGGGI GFTLFEMLRY PTIEKIDIVE IDDVVVDVSR
190 200 210 220 230 240
KFFPYLAANF NDPRVTLVLG DGAAFVKAAQ AEYYDAIIVD SSDPIGPAKD LFERPFFEAV
250 260 270 280 290 300
AKALRPGGVV CTQAESIWLH MHIIKQIIAN CRQVFKGSVN YAWTTVPTYP TGVIGYMLCS
310 320 330 340 350
TEGPEIDFKN PVNPIDKETA QVKSKLAPLK FYNSDIHKAA FILPSFARSM IES