Q9SC14
Gene name |
DHS1 |
Protein name |
Deoxyhypusine synthase |
Names |
DHS |
Species |
Senecio vernalis (Spring groundsel) |
KEGG Pathway |
ag:CAB65461 |
EC number |
2.5.1.46: Transferring alkyl or aryl groups, other than methyl groups |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9SC14
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9SC14-F1 | Predicted | AlphaFoldDB |
No variants for Q9SC14
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9SC14 | |||||
No associated diseases with Q9SC14
No regional properties for Q9SC14
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q9SC14 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.5.1.46 | Transferring alkyl or aryl groups, other than methyl groups |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| deoxyhypusine synthase activity | Catalysis of the reaction: -lysine = N-(4-aminobutylidene)--lysine + propane-1,3-diamine; N-(4-aminobutylidene)--lysine = N-(4-aminobutylidene)--lysine; N-(4-aminobutylidene)- |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| peptidyl-lysine modification to peptidyl-hypusine | The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEESMKQASV | MENLRSVVFK | ESESLEGTCA | KIRGYDFNNG | IDYSQILKSM | VSTGFQASNL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GDAIETVNQM | LDWRLSHEQV | TEDCSQEEKN | PTYRESIKCK | IFLGFTSNLI | SSGVRDIIRY |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LVQHHMVDVI | VTTTGGIEED | LIKCLADTFK | GEFSLPGAEL | RSKGLNRIGN | LLVPNDNYCK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FEDWIIPIFD | QMLEEQKAKN | VLWTPSKLIM | RLGKEINNES | SYLYWAYKND | IPVFCPGLTD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GSLGDMLYFH | TFRNPGLIVD | VVQDIRAINS | EAVHANPRKT | GMIILGGGLP | KHHICNANMM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| RNGADYAVFI | NTAQEFDGSD | SGARPDEAVS | WGKIRGSAKS | VKVHCDATIA | FPLLVAETFA |
| 370 | |||||
| AKREQSAEPS | S |