Q9RYW7

PR
Gene name
rimO
Protein name
Ribosomal protein S12 methylthiotransferase RimO
Names
S12 MTTase, S12 methylthiotransferase, Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase, Ribosome maturation factor RimO
Species
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
KEGG Pathway
dra:DR_A0189
EC number
2.8.4.4: Transferring alkylthio groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9RYW7

Entry ID Method Resolution Chain Position Source
AF-Q9RYW7-F1 Predicted AlphaFoldDB

No variants for Q9RYW7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9RYW7

No associated diseases with Q9RYW7

6 regional properties for Q9RYW7

Type Name Position InterPro Accession
domain TRAM domain 411 - 487 IPR002792
domain Elp3/MiaA/NifB-like, radical SAM core domain 176 - 400 IPR006638
domain Radical SAM 19 - 487 IPR007197
domain Methylthiotransferase, N-terminal 21 - 131 IPR013848
conserved_site Methylthiotransferase, conserved site 180 - 200 IPR020612
domain RimO, TRAM domain 414 - 486 IPR041582

Functions

Description
EC Number 2.8.4.4 Transferring alkylthio groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

4 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
aspartic acid methylthiotransferase activity Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.
metal ion binding Binding to a metal ion.
protein methylthiotransferase activity Catalysis of the reaction: 2 S-adenosyl-L-methionine + a

1 GO annotations of biological process

Name Definition
tRNA modification The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MEDDVTTTER LPAPPLDTAS KRVGFISLGC PKALVDSERI LTQLRAEGYE VAPSYEGADA
70 80 90 100 110 120
VIVNTCGFIT PAVEESLSAI GEALDATGKV IVTGCLGERP EKIMERHPKV AAITGSEAVD
130 140 150 160 170 180
DVMGHVRELL PIDQGAFTGL LPVAAPGMRA GVETPQRENT RHGDVFAPSV KLTPRHYAYV
190 200 210 220 230 240
KVAEGCNHTC AFCIIPKLRG LQVSRDAGAV LYEAYRLIAG GTKELMIIAQ DTSAYGVDLR
250 260 270 280 290 300
YRESEFQGEQ VRAHLTDLAV KLGEMGAWVR MHYVYPYPHV DRVVELMAQG KVLPYLDIPL
310 320 330 340 350 360
QHASPKILKL MRRPGAGKQL DTIRRWREIC PELVIRSTFI VGFPGETEED FQELLQFLED
370 380 390 400 410 420
ARLDRVGAFP YSDIEEADAN ALPGAVPEEV KQERLARFME VAQRISTEKL SEKVGRVMDV
430 440 450 460 470 480
IIDEFNDDED DQPGTRLIGR TKGDAPGIDG QVYLYAGDFA GLVKIGDIVR ARIEDSDEYD
490 500
LFGEVIEKPE WKPNVPQLGH FGKH