Q9RWJ0

PR
Gene name
argH
Protein name
Argininosuccinate lyase
Names
ASAL, Arginosuccinase
Species
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
KEGG Pathway
dra:DR_0678
EC number
4.3.2.1: Lyases acting on amides, amidines, etc
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

168-324 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9RWJ0

Entry ID Method Resolution Chain Position Source
AF-Q9RWJ0-F1 Predicted AlphaFoldDB

No variants for Q9RWJ0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9RWJ0

No associated diseases with Q9RWJ0

3 regional properties for Q9RWJ0

Type Name Position InterPro Accession
conserved_site Fumarate lyase, conserved site 284 - 293 IPR020557
domain Fumarate lyase, N-terminal 13 - 309 IPR022761
domain Argininosuccinate lyase, C-terminal 372 - 439 IPR029419

Functions

Description
EC Number 4.3.2.1 Lyases acting on amides, amidines, etc
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

1 GO annotations of molecular function

Name Definition
argininosuccinate lyase activity Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.

1 GO annotations of biological process

Name Definition
arginine biosynthetic process via ornithine The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTNQKQETKL WGGRFAEKTA ELVELFNASV GFDQRLAEQD IRGSLAHVAM LGGQGILTAE
70 80 90 100 110 120
EVSQITDGLN GVLADIRAGN FEWRLDREDV HMNVEAALRD RIGPVAGKLH TARSRNDQVA
130 140 150 160 170 180
VDFRLFTKEA ALDLAEQTRA LRRVMLAEAE KHLQNEVILP GYTHLQVAQP ILLAHWFMAY
190 200 210 220 230 240
VAMLERDEGR FRDAAERMDE SPLGSSALAG TPWPLDRHAT AEALGFARPT ANSLDGVGSR
250 260 270 280 290 300
DFALEFLSAC AILSAHLSRL SEELILYSTF EFGFITLPDS HTTGSSIMPQ KKNPDVSELA
310 320 330 340 350 360
RGKAGRVFGN LMALLTVVKG TPLAYNKDLQ EDKEGVFDSY DTLSIVLRLY AEMLPKTVWH
370 380 390 400 410 420
ADVTKAAAAR GYSTATDVAD YLARQGVPFR EAHEVVGGLV GLASRSDRQL WELTDAELKA
430 440 450 460 470
AHPLLSAEVA QKLTVEESVR SRQSYGGTAP ERVREAVEAA KEKLRQETGQ P