Q9RU81

PR
Gene name
pyrH
Protein name
Uridylate kinase
Names
UK, Uridine monophosphate kinase, UMP kinase, UMPK
Species
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
KEGG Pathway
dra:DR_1511
EC number
2.7.4.22: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

40-109 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9RU81

Entry ID Method Resolution Chain Position Source
AF-Q9RU81-F1 Predicted AlphaFoldDB

No variants for Q9RU81

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9RU81

No associated diseases with Q9RU81

3 regional properties for Q9RU81

Type Name Position InterPro Accession
domain CTP synthase, N-terminal 3 - 267 IPR017456
domain Glutamine amidotransferase 302 - 526 IPR017926
domain CTP synthase GATase domain 291 - 525 IPR033828

Functions

Description
EC Number 2.7.4.22 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
UMP kinase activity Catalysis of the reaction: ATP + UMP = ADP + UDP.

3 GO annotations of biological process

Name Definition
'de novo' CTP biosynthetic process The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
UDP biosynthetic process The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLKRREPDMF KRVLLKLSGE FLAGDNGFGI SPETTAELAR RIIGALDGTE VELAVVIGGG
70 80 90 100 110 120
NLWRGARNGQ GMDPATADYI GMLGTVMNAM ALQDAMEAAG KPTRIMSAIH MQQVAEPYIR
130 140 150 160 170 180
RRAMRHLEKG RVVIFGGGNG APFFTTDTTS TLRALEIGAD VVLMAKNAVD GVYDSDPRKN
190 200 210 220 230 240
PDAKRYEQLT HMDVVEQRLE VMDATALTLC MDKGLPIVVF DIFEEGNLAR LLRGERVGTL
IQSRG