Q9RSY5

PR
Gene name
tdk
Protein name
Thymidine kinase
Names
Species
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
KEGG Pathway
dra:DR_1984
EC number
2.7.1.21: Phosphotransferases with an alcohol group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

158-212 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9RSY5

Entry ID Method Resolution Chain Position Source
AF-Q9RSY5-F1 Predicted AlphaFoldDB

No variants for Q9RSY5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9RSY5

No associated diseases with Q9RSY5

1 regional properties for Q9RSY5

Type Name Position InterPro Accession
conserved_site Thymidine kinase, conserved site 182 - 195 IPR020633

Functions

Description
EC Number 2.7.1.21 Phosphotransferases with an alcohol group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
thymidine kinase activity Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.

3 GO annotations of biological process

Name Definition
DNA biosynthetic process The biosynthetic process resulting in the formation of DNA.
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
thymidine metabolic process The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRSPYSGGH LEVVVGPMFS GKSEELIRRL TRSLIARQRV AVFKPAIDNR YHASEVASHA
70 80 90 100 110 120
GRTLEAVAVP DAQAIRAQLS GQGELLSAAP EGVDVIGIDE AQFFGPELVP LVLELADAGV
130 140 150 160 170 180
RVVLAGLDLD FRAEPFGSMP ELLARAESVD KLTAICTVCG APATRTQRLI GGQPARFDDP
190 200 210
VVLVGAQESY EALPRAPHRA QGGVTTPSPL AS