Q9RSR1
Gene name |
pnp |
Protein name |
Polyribonucleotide nucleotidyltransferase |
Names |
Polynucleotide phosphorylase, PNPase |
Species |
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422) |
KEGG Pathway |
dra:DR_2063 |
EC number |
2.7.7.8: Nucleotidyltransferases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9RSR1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9RSR1-F1 | Predicted | AlphaFoldDB |
No variants for Q9RSR1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9RSR1 | |||||
No associated diseases with Q9RSR1
9 regional properties for Q9RSR1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exoribonuclease, phosphorolytic domain 1 | 13 - 142 | IPR001247-1 |
| domain | Exoribonuclease, phosphorolytic domain 1 | 328 - 460 | IPR001247-2 |
| domain | S1 domain | 622 - 693 | IPR003029 |
| domain | K Homology domain | 556 - 620 | IPR004087 |
| domain | K Homology domain, type 1 | 561 - 616 | IPR004088 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 146 - 207 | IPR015847-1 |
| domain | Exoribonuclease, phosphorolytic domain 2 | 463 - 533 | IPR015847-2 |
| domain | Polyribonucleotide nucleotidyltransferase, RNA-binding domain | 253 - 324 | IPR015848 |
| domain | RNA-binding domain, S1 | 623 - 693 | IPR022967 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.7.8 | Nucleotidyltransferases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 3'-5'-exoribonuclease activity | Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule. |
| magnesium ion binding | Binding to a magnesium (Mg) ion. |
| polyribonucleotide nucleotidyltransferase activity | Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate. |
| RNA binding | Binding to an RNA molecule or a portion thereof. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA catabolic process | The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes. |
| RNA catabolic process | The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. |
| RNA processing | Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MIGKTFTTML | GGRELSIETG | KLAKLVSGSV | TVRYGDTLLL | VTAQASDTQS | KLDFLPLTVE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FEERHYAVGK | IPGSFQRREG | RPGEKAILSA | RITDRQIRPL | FPKGYRHETQ | VIITVLSADG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QNAPDVLGPI | GAAAALSISD | IPWAGPTACV | RVGQIDGQYV | VNPTTEQLTR | SRMDLVVAGT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| REAVMMVECG | AQTVSEDDLV | GAIEFAHAEM | QGVIALIEQM | RAEVGHEKFN | FLAEEGPAND |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YVPELTEKAK | AAGLRDALLT | HGKKDRSARL | KALRNGLIEG | YVPDPTAEGS | AELTQALKDA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FGKVEKRELR | RLILEENLRA | DGRDSKTVRP | IWIEARPLPT | AHGSAVFTRG | ETQVLGVTTL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| GTERDEILID | DLTAESGDKF | LLHYNFPPYS | TGEVKRMGGQ | SRREIGHGNL | AKRAIRAVLP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| SFEEFPYVIR | VVGDVLESNG | SSSMGTVCAG | TLSLMDAGVP | LKAPVAGVAM | GLVMEGDNYR |
| 490 | 500 | 510 | 520 | 530 | 540 |
| VLTDILGLED | ALGDMDFKVC | GTAEGVTALQ | MDIKVGGITP | QIMREALAQA | KEGRLHILGK |
| 550 | 560 | 570 | 580 | 590 | 600 |
| MAEVLAAPRA | ELSPTAPHIL | SLKINPELIG | KVIGPGGKQV | RELEAMGAQV | TIEEDGTVRI |
| 610 | 620 | 630 | 640 | 650 | 660 |
| FSASGESAEA | VKARIEAVTK | EAKVGEEFEG | TVVKIAPFGA | FVNLFPGQDG | MLHISQLSEQ |
| 670 | 680 | 690 | 700 | 710 | 720 |
| RVENVEDVLT | VGDKLKVKIA | NIDDRGKIDL | IRPELEGKVP | LREPRAPRGG | DRGPRRDSDR |
| 730 | 740 | 750 | 760 | 770 | |
| GGDRGPRREF | SDRGPRPEGA | RSERPEGQRT | ERPATAPATQ | ESSQSSDAPA | APVFPRRED |