Q9RRU7

PR
Gene name
lspA
Protein name
Lipoprotein signal peptidase
Names
Prolipoprotein signal peptidase, Signal peptidase II, SPase II
Species
Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)
KEGG Pathway
dra:DR_2388
EC number
3.4.23.36: Aspartic endopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-48 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9RRU7

Entry ID Method Resolution Chain Position Source
AF-Q9RRU7-F1 Predicted AlphaFoldDB

No variants for Q9RRU7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9RRU7

No associated diseases with Q9RRU7

No regional properties for Q9RRU7

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9RRU7

Functions

Description
EC Number 3.4.23.36 Aspartic endopeptidases
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

1 GO annotations of biological process

Name Definition
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWPFSRQQNV SRILPIVPTA PRRFPVWFPA VLVLVLIALD QWLKAWALAH LQLNAPAIPV
70 80 90 100 110 120
IPGVLDWELT FNTGAAWSMF SGSAVPLALG RILVGLGILS YLLWKPQGRF LTVVLSMIAA
130 140 150 160 170 180
GAIGNSIDGL QRGQVTDMIH SPLLSAVTEA INGTRFPIFN IADMCVVGGT ILLLVASLLP
190
ERKREKAVPE A