Q9PWF7

PR
Gene name
cat
Protein name
Catalase
Names
Species
Glandirana rugosa (Japanese wrinkled frog) (Rana rugosa)
KEGG Pathway
EC number
1.11.1.6: Peroxidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-63 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9PWF7

Entry ID Method Resolution Chain Position Source
AF-Q9PWF7-F1 Predicted AlphaFoldDB

No variants for Q9PWF7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9PWF7

No associated diseases with Q9PWF7

4 regional properties for Q9PWF7

Type Name Position InterPro Accession
binding_site Catalase haem-binding site 354 - 362 IPR002226
domain Catalase immune-responsive domain 435 - 496 IPR010582
domain Catalase core domain 28 - 413 IPR011614
active_site Catalase active site 64 - 80 IPR024708

Functions

Description
EC Number 1.11.1.6 Peroxidases
Subcellular Localization
  • Peroxisome matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
peroxisome A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.

3 GO annotations of molecular function

Name Definition
catalase activity Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
heme binding Binding to a heme, a compound composed of iron complexed in a porphyrin (tetrapyrrole) ring.
metal ion binding Binding to a metal ion.

2 GO annotations of biological process

Name Definition
hydrogen peroxide catabolic process The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
response to oxidative stress Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADRREKSAD QMKLWKESRA NQKPDVLTTG GGNPVSDKLN LLTVGPRGPL LVQDVVFTDE
70 80 90 100 110 120
MAHFDRERIP ERVVHAKGAG AFGYFEVTHD ITRYSKAKVF EFIGKRTPIA VRFSTVAGEA
130 140 150 160 170 180
GSADTVRDPR GFAVKFYTED GNWDLTGNNT PIFFVRDAML FPSFIHSQKR NPQTHMKDPD
190 200 210 220 230 240
MVWDFWALRP ESLHQVSFLF SDRGIPDGHR HMNGYGSHTF KLVNAKDEPI YCKFHFKTDQ
250 260 270 280 290 300
GIRNLTVEEA NRLSAEDPDY GIHDLYEAIA NGNYPSWTFY IQVMTFEQAE RYPFNPFDLT
310 320 330 340 350 360
KIWPHKDYPL IPVGKLVLNR NPANYFAEVE QIAFDPSNMP PGIEPSPDKM LQGRLFSYPD
370 380 390 400 410 420
THRHRLGANY LQLPVNCPYK ARVANYQRDG PMCFSDNQGG APNYFPNSFS APENQPAARE
430 440 450 460 470 480
SKFRVSADVA RYNSSDDDNV SQVRDFYTKV LSEEERKRLC ENIAGHLKGA QIFIQKRAVK
490 500 510 520
NFTDVHPDYG NRVQALLDKY NAEGHHKKVI KTYTQHSAHV TANDKANL