Q9PVG3
Gene name |
rest-b (nrsf-b) |
Protein name |
RE1-silencing transcription factor B |
Names |
Neural-restrictive silencer factor B |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:373614 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9PVG3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9PVG3-F1 | Predicted | AlphaFoldDB |
No variants for Q9PVG3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9PVG3 | |||||
No associated diseases with Q9PVG3
8 regional properties for Q9PVG3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger C2H2-type | 156 - 178 | IPR013087-1 |
| domain | Zinc finger C2H2-type | 212 - 234 | IPR013087-2 |
| domain | Zinc finger C2H2-type | 244 - 266 | IPR013087-3 |
| domain | Zinc finger C2H2-type | 272 - 299 | IPR013087-4 |
| domain | Zinc finger C2H2-type | 300 - 327 | IPR013087-5 |
| domain | Zinc finger C2H2-type | 328 - 356 | IPR013087-6 |
| domain | Zinc finger C2H2-type | 357 - 384 | IPR013087-7 |
| domain | Zinc finger C2H2-type | 385 - 413 | IPR013087-8 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
5 GO annotations of biological process
| Name | Definition |
|---|---|
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| positive regulation of neuron differentiation | Any process that activates or increases the frequency, rate or extent of neuron differentiation. |
| regulation of alternative mRNA splicing, via spliceosome | Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs. |
| regulation of osteoblast differentiation | Any process that modulates the frequency, rate or extent of osteoblast differentiation. |
| response to hypoxia | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MATQMVNQST | GNSLFCTSTY | SNISLDNDMY | GLHDLSKADM | AAPRLIMLAN | VALTGELSSG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CCDYTPEGER | QMAELTTVND | NSFSDSEGDR | LEDSPSMDIQ | SHNFIMEMEP | AECSKEGTSE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NDGTLLSNTL | EVEVQKDKRT | PSPTDDKYKC | VKSKPFRCKP | CQYKAESEEE | FVHHIKIHSA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KIYVDNDSNK | KAQGNEADSS | ISEESDVSKG | PIQCDRCGYN | TNRFDHYLAH | LKHHNKAGEN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ERVYKCTICT | YTTVSEYHWK | KHLRNHYPRI | LYTCSQCSYF | SDRKNNYIQH | IRTHTGERPY |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QCILCPYSSS | QKTHLTRHMR | THSGEKPFKC | EQCSYVASNQ | HEVTRHARQV | HNGPKPLTCP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| HCDYKTADRS | NFKKHVELHV | NPRQFLCPVC | DYAASKKCNL | QYHIKSRHSG | CTNITMDVSK |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VKLRTKKGDI | GVADVDANKQ | TENGNIIDKS | VEETVKAEKR | ESCGKAKKSI | VNLVDGQVAK |
| 490 | 500 | 510 | 520 | ||
| KRRLSSTQKK | IKTSDARPEK | ILDKSRKSSC | VKRKSDLLEN | SNDTQTSTV |