Q9PU13

PR
Gene name
spdya-a
Protein name
Speedy protein 1-A
Names
Spy1-A, Protein Ls26, Rapid inducer of G2/M progression in oocytes A, RINGO-A, XSpy1-A, p33 ringo-A, xRINGO-A
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:398012
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-79 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9PU13

Entry ID Method Resolution Chain Position Source
AF-Q9PU13-F1 Predicted AlphaFoldDB

No variants for Q9PU13

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9PU13

No associated diseases with Q9PU13

No regional properties for Q9PU13

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q9PU13

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
cyclin binding Binding to cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
protein kinase binding Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.

6 GO annotations of biological process

Name Definition
G2/MI transition of meiotic cell cycle The cell cycle process in which a cell progresses from meiotic G2 phase to M phase of meiosis I.
mRNA polyadenylation The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
oocyte maturation A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
positive regulation of cyclin-dependent protein serine/threonine kinase activity Any process that activates or increases the frequency, rate or extent of CDK activity.
positive regulation of MAPK cascade Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
positive regulation of meiotic cell cycle Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRHMQSVTRA TSICGSGVKQ VIGKGHPHAR VVGARKARIP EREELSVKPK MVRNTHLNLQ
70 80 90 100 110 120
PQERQAFYRL LENEQIQEFL SMDSCLRISD KYLIAMVLAY FKRAGLYTSE YTTMNFFVAL
130 140 150 160 170 180
YLANDMEEDE EDYKYEIFPW ALGDSWRELF PQFLRLRDDF WAKMNYRAVV SRRCCDEVMS
190 200 210 220 230 240
KDPTHWAWLR DRPIHHSGAM RGYLRNEDDF SPRGPGLTPA SCTLCHKAGV CDSGGVSHNN
250 260 270 280 290
SSSPEQEIFH YTNREWSQEL LMLSPELLLD PECTHDLHIL QEPLVGLEPD GTALEWHHL