Q9PRJ8
Gene name |
foxd5-a (foxd5a) |
Protein name |
Forkhead box protein D5-A |
Names |
FoxD5-A, FoxD5a, Fork head domain-related protein 12, xFD-12, XlFoxD5a |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:398170 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9PRJ8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9PRJ8-F1 | Predicted | AlphaFoldDB |
No variants for Q9PRJ8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9PRJ8 | |||||
No associated diseases with Q9PRJ8
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| DNA binding | Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
| DNA-binding transcription factor activity | A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons. |
| sequence-specific DNA binding | Binding to DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
6 GO annotations of biological process
| Name | Definition |
|---|---|
| cell differentiation | The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. |
| dorsal/ventral pattern formation | The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism. |
| negative regulation of DNA-templated transcription | Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription. |
| nervous system development | The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. |
| neural plate development | The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. |
| regulation of DNA-templated transcription | Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFSQESGAH | HHPQDYAGLS | DEEDEIDILG | EDDPCSLKSH | FYLQPTHSVM | GDSEMLSPSK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LSCTESESDS | SGESEGGTSK | DSSTTPTGSK | AKRTLVKPPY | SYIALITMAI | LQSPHKKLTL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SGICDFISSK | FPYYKDKFPA | WQNSIRHNLS | LNDCFIKIPR | EPGNPGKGNY | WTLDPASEDM |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FDNGSFLRRR | KRFKRHQQEF | FKDGLMMYNS | LPYYRPYSAI | QPQPVLQQTS | LTCMAIPETL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| PMSTHLAPYP | DIKRKVSYPA | QGVHRGFKAQ | DADNHPNNSQ | SKCSFSIENI | MRKPKEPEPN |
| 310 | 320 | 330 | 340 | 350 | |
| IQSFNSHWNY | NHVFQRPSSC | LLPAVLNLST | GPLLANTQGA | RQYNLIQFPG | CY |