Q9PPP5
Gene name |
tdk |
Protein name |
Thymidine kinase |
Names |
|
Species |
Ureaplasma parvum serovar 3 (strain ATCC 700970) |
KEGG Pathway |
uur:UU594 |
EC number |
2.7.1.21: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
3 structures for Q9PPP5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 2B8T | X-ray | 200 A | A/B/C/D | 1-223 | PDB |
| 2UZ3 | X-ray | 250 A | A/B/C/D | 1-223 | PDB |
| AF-Q9PPP5-F1 | Predicted | AlphaFoldDB |
No variants for Q9PPP5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9PPP5 | |||||
No associated diseases with Q9PPP5
1 regional properties for Q9PPP5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Thymidine kinase, conserved site | 182 - 195 | IPR020633 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.21 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| thymidine kinase activity | Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate. |
| zinc ion binding | Binding to a zinc ion (Zn). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA biosynthetic process | The biosynthetic process resulting in the formation of DNA. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKVNAFSKK | IGWIELITGP | MFAGKTAELI | RRLHRLEYAD | VKYLVFKPKI | DTRSIRNIQS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RTGTSLPSVE | VESAPEILNY | IMSNSFNDET | KVIGIDEVQF | FDDRICEVAN | ILAENGFVVI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ISGLDKNFKG | EPFGPIAKLF | TYADKITKLT | AICNECGAEA | THSLRKIDGK | HADYNDDIVK |
| 190 | 200 | 210 | 220 | ||
| IGCQEFYSAV | CRHHHKVPNR | PYLNSNSEEF | IKFFKNKKRN | KNI |