Q9PLM5

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Chlamydia muridarum (strain MoPn / Nigg)
KEGG Pathway
cmu:TC_0074
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

907-968 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9PLM5

Entry ID Method Resolution Chain Position Source
AF-Q9PLM5-F1 Predicted AlphaFoldDB

No variants for Q9PLM5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9PLM5

No associated diseases with Q9PLM5

8 regional properties for Q9PLM5

Type Name Position InterPro Accession
domain Helicase, C-terminal 541 - 725 IPR001650
domain SecA DEAD-like, N-terminal 5 - 521 IPR011115
domain SecA Wing/Scaffold 709 - 928 IPR011116
domain SecA, preprotein cross-linking domain 337 - 477 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 101 - 260 IPR014001
domain SecA motor DEAD 2 - 709 IPR014018
conserved_site SecA conserved site 619 - 634 IPR020937
domain SecA, C-terminal helicase domain 539 - 679 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell inner membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMDFLKRFFG SSQERILKRF QKLVEEVNAC DEKFSSLSDD ELREKTPQLK RRYQEGESLD
70 80 90 100 110 120
KLLPEAYGIV KNVCRRLAGT PVEVSGYHQQ WDMVPYDVQI LGGIAMHKGF ITEMQTGEGK
130 140 150 160 170 180
TLTAVMPLYL NALTGKPVHL VTVNDYLAQR DCEWVGSVLR WLGLTTGVLV SGIPPERRKA
190 200 210 220 230 240
IYQCDVVYGT ASEFGFDYLR DNSIATRKEE QVGRGFYFAI IDEVDSVLID EARTPLIISG
250 260 270 280 290 300
PGEKHNPVYF ELKDKVAELV HFQREMCNHI AAEARKTLDP FLGMDVLPKD RKIMEGISEA
310 320 330 340 350 360
CRALWLVSKG MPLNRVLRRV REHPDLRAMV DKWDVFYHAE QNKEECLERL SSLYIVVDEH
370 380 390 400 410 420
NNDFELTDKG MQQWIEKIGG AAEDFVMMDM GHEYALIEED TTLSPEDKLN RKIAVSEKDT
430 440 450 460 470 480
QRKARAHGLR QLLRAHLLME RDIDYIVRDD QIVIIDEHTG RPQAGRRFSE GLHQAIEAKE
490 500 510 520 530 540
HVTIRKESQT FATVTLQNFF RLYEKLAGMT GTAITESREF KEIYNLYVLQ VPTFKPCLRI
550 560 570 580 590 600
DHNDAFYMTE REKYQAIVAE IISAHRSGKP ILIGTESVEV SEKLSRILRQ NRIHHTVLNA
610 620 630 640 650 660
KNHAQEAEII AGAGKVGAVT VATNMAGRGT DIKLDKEAVA AGGLYVIGTS RHQSRRIDRQ
670 680 690 700 710 720
LRGRCARLGD PGAAKFFLSF EDRLMRLFAS PKLNTLIRHF RPPEGEAMSD PMFDRLIETA
730 740 750 760 770 780
QKRVEGRNYT IRKHTLEYDD VMNKQRQTIY AFRNDVLHAD DLFIVAREQI EHVSLALAFL
790 800 810 820 830 840
ILKDARADHC SLPKVEEWLS YSFPVKLDDQ EIRRLGNVDA VADYIGGLLI EAFDAKFSSM
850 860 870 880 890 900
LTEFTEIIGS ASGAQGVCND ILRSVIISHI DEEWKVHLMD MDLLRSEVGL RSVGQKDPLI
910 920 930 940 950 960
EFKNESFLLF EGLIRDIRIA IVKHLFALEL SLTRSDRPDN AIPTVATAFH NHDNFRPMEL
TIIGEEEN