Q9PL93

PR
Gene name
nrdA (TC_0214)
Protein name
Ribonucleoside-diphosphate reductase subunit alpha
Names
Ribonucleotide reductase
Species
Chlamydia muridarum (strain MoPn / Nigg)
KEGG Pathway
cmu:TC_0214
EC number
1.17.4.1: With a disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

976-1047 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9PL93

Entry ID Method Resolution Chain Position Source
AF-Q9PL93-F1 Predicted AlphaFoldDB

No variants for Q9PL93

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9PL93

No associated diseases with Q9PL93

2 regional properties for Q9PL93

Type Name Position InterPro Accession
domain Transcription regulator HTH, LysR 6 - 66 IPR000847
domain LysR, substrate-binding 95 - 296 IPR005119

Functions

Description
EC Number 1.17.4.1 With a disulfide as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.

1 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVDLQEKQCT IVKRNGMFVP FDRNRIFQAL EAAFRDTRRI DDHMPLPEDL ENSIRSITHQ
70 80 90 100 110 120
VVKEVVQKIT DGQVVTVERI QDMVESQLYI NGLQDVARDY VVYRDDRKAH REKSWQSLSV
130 140 150 160 170 180
IRRCGTTVHF NPMKISAALE KAFRATDRIE GMTPDFVREE VNALTQKIVA EIEERCSQQD
190 200 210 220 230 240
SRIDIEQIQD IVEQQLMVVG HYATAKNYIL YREARARVRD NRVEDQIVEE APSEETFEVL
250 260 270 280 290 300
SKDGSTYMIT HSQLLARLAR ACSRFPETTD AALLTDMAFS NFYSGIKESE VVLACIMAAR
310 320 330 340 350 360
ANIEKEPDYA FVAAELLLDV VYKEALDRSR GDEDLEQVYR DHFKRYIMEG DSYRLNPELK
370 380 390 400 410 420
NLFDLDALAN AMDLSRDLQF SYMGIQNLYD RYFNHDDGRR LETPQIFWMR VAMGLALKEQ
430 440 450 460 470 480
DKTYWAITFY NLLSTFRYTP ATPTLFNSGM RHSQLSSCYL STVQDDLVNI YKVISDNAML
490 500 510 520 530 540
SKWAGGIGND WTAIRATGAL IKGTNGKSQG VIPFIKVTND TAVAVNQGGK RKGAVCVYLE
550 560 570 580 590 600
VWHLDYEDFL ELRKNTGDDR RRAHDVNTAS WIPDLFFKRL QQKGSWTLFS PDDVPGLHDA
610 620 630 640 650 660
YGEEFERLYE EYERKVDSGE IRLYKKVEAE DLWRKMLSML FETGHPWMTF KDPSNIRSAQ
670 680 690 700 710 720
DHTGVVRCSN LCTEILLNCS ETETAVCNLG SVNLVQHILD DGLDEEKLSE TISIAVRMLD
730 740 750 760 770 780
NVIDINFYPT KEAKEANFAH RAIGLGVMGF QDALYKLDIS YASQEAVEFA DYSSELISYY
790 800 810 820 830 840
AIQASCLLAK ERGTYSSYKG SKWDRGLLPI DTIQLLANYR GKDNLQMDTS VRKDWEPIRS
850 860 870 880 890 900
LIREHGMRNC QLMAIAPTAT ISNIIGVTQS IEPTYKHLFV KSNLSGEFTI PNVYLIEKLK
910 920 930 940 950 960
KLGIWDADML DDLKYFDGSL LEIERVPDHI KHIFLTAFEI EPEWILECAS RRQKWIDMGQ
970 980 990 1000 1010 1020
SLNLYLAQPD GKKLSNMYLT AWKKGLKTTY YLRSSSATTV EKSFVDINKR GIQPRWMKNK
1030 1040
SASAGIVVER ASKTPVCSLE EGCEVCQ