Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9PGR3

Entry ID Method Resolution Chain Position Source
AF-Q9PGR3-F1 Predicted AlphaFoldDB

No variants for Q9PGR3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9PGR3

No associated diseases with Q9PGR3

6 regional properties for Q9PGR3

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 391 - 560 IPR000795
domain Small GTP-binding protein domain 394 - 549 IPR005225
domain Translation initiation factor IF-2, N-terminal 315 - 365 IPR006847
domain Initiation factor 2 associated domain, bacterial 69 - 105 IPR013575
domain Translation initiation factor IF- 2, domain 3 669 - 782 IPR023115
domain Translation initiation factor IF-2, domain II 566 - 660 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSQQTTIRKL AELVNTPVEK LLEQLAGAGM KFSGPDQVVT STEKMKLLGF LRRTHGKSDV
70 80 90 100 110 120
SVGAVREAPK KITLNRRRLQ EVTVNAGRNK TTVNVEVRQK RTYVKTPESE YHTPTKPPIE
130 140 150 160 170 180
LGDAERVEIL RKLEESRQRN LAEQQRLAEV DRQRVEEQER KRLEEEQAEL ERQKTESPVV
190 200 210 220 230 240
EEVPVQSDSN SVKPVSKPIS EDRTRALPRA VRPAPAARPS VSRSDDRNSN SGVRHKPRGS
250 260 270 280 290 300
HVIVSDEDDS ARRFAGQMHL TAAERARRGS NTRGKGGGSH RGATHRGNEN SIRSSGAHGF
310 320 330 340 350 360
ERPTAAVVRE VAVGDTITVA DLAQKLALKS GDMVKALFKM GVMVTITQTI DHDTAVLVSE
370 380 390 400 410 420
ELGHKVTRAS SSDFEDALLA HTEEVHGEPV PRPPVVTIMG HVDHGKTSLL DYIRRTKIAV
430 440 450 460 470 480
GEAGGITQHI GAYHVETPRG VISFLDTPGH AAFTSMRARG AKITDIVVLV VAADDGVMPQ
490 500 510 520 530 540
TKEAVQHARA AGVPLIVAVS KIDKSTADPQ RVKNELLTES VVAEEFGGDT QFVELSAKTG
550 560 570 580 590 600
VGVDALLDAI SIQAEVLELK AVIEGRATGT VIESSLDKGR GPVATVLVQQ GRLKKGDYLV
610 620 630 640 650 660
CGTHYGRVRA LFDEVGHQPL AASPSIPVQV LGLSGVPDAG DDFVVVDDER LAKDVAQQRE
670 680 690 700 710 720
AKRRESRLVT SAGNRMEDIL AQMGKGENQQ VLNLLIKADV QGSLEALKQA LVALSNDDIR
730 740 750 760 770 780
INVIHVGVGG ITESDANSAV TSKATVIGFN VRADASARKI IEANGVDLRY FSIIYDVIDQ
790 800 810 820 830 840
VKQVASGLLG VEIREEIIGV AEVRDVFRSS KFGAVAGCMI IEGVVKRSKP IRVLRDNTVV
850 860 870 880 890
FEGELESLRR FKENVDEVRN STECGIGVKA YNDVRVGDHI ECFERIEVAR TL