Q9P8V0
Gene name |
RHO4 (ACR257C) |
Protein name |
GTP-binding protein RHO4 |
Names |
|
Species |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
KEGG Pathway |
ago:AGOS_ACR257C |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9P8V0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9P8V0-F1 | Predicted | AlphaFoldDB |
No variants for Q9P8V0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9P8V0 | |||||
No associated diseases with Q9P8V0
5 regional properties for Q9P8V0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | ELM2 domain | 44 - 129 | IPR000949 |
| domain | SANT/Myb domain | 131 - 179 | IPR001005-1 |
| domain | SANT/Myb domain | 328 - 376 | IPR001005-2 |
| domain | SANT domain | 130 - 181 | IPR017884-1 |
| domain | SANT domain | 327 - 378 | IPR017884-2 |
7 GO annotations of cellular component
| Name | Definition |
|---|---|
| cell cortex | The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. |
| cell projection | A prolongation or process extending from a cell, e.g. a flagellum or axon. |
| cellular bud neck | The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding. |
| cytoplasmic vesicle | A vesicle found in the cytoplasm of a cell. |
| cytoskeleton | A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. |
| incipient cellular bud site | The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| GTP binding | Binding to GTP, guanosine triphosphate. |
| GTPase activity | Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate. |
| protein kinase binding | Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. |
8 GO annotations of biological process
| Name | Definition |
|---|---|
| actin filament organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. |
| cortical cytoskeleton organization | A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane. |
| establishment or maintenance of cell polarity | Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. |
| maintenance of cell polarity | The maintenance of established anisotropic intracellular organization or cell growth patterns. |
| positive regulation of formin-nucleated actin cable assembly | Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. |
| regulation of actin cytoskeleton organization | Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. |
| regulation of cell shape | Any process that modulates the surface configuration of a cell. |
| small GTPase mediated signal transduction | The series of molecular signals in which a small monomeric GTPase relays a signal. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSAGPLQAAP | KKNYGALIGA | GPAVGGAAFN | RTLSEVASYE | RSRRDHATPD | YRIKIVVVGD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| GATGKTSLLM | SYTQGQFPED | YVPTIFENYV | TNIEGPRGKV | IELALWDTAG | QEEYSRLRPL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| SYGDVDIVMV | CYAADNRTSL | TNAEELWFPE | VRHFCPHAPM | MLVGLKSDLY | SLDALDRLVD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| PTDAELVARK | MGAFVHLQCS | AKTRQCLEDV | FNTAIHTALY | DELRAPPQRG | VKGMFKKKQQ |
| 250 | |||||
| RDPQAQSYKR | VRKHRCVVL |