Q9P7S3
Gene name |
ssr3 (SPAC23G3.10c) |
Protein name |
SWI/SNF and RSC complexes subunit ssr3 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC23G3.10c |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9P7S3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9P7S3-F1 | Predicted | AlphaFoldDB |
2 variants for Q9P7S3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_887124_C_T | 17 | G>R | No | Jeffares_SNPs | |
| I_886562_T_A | 204 | E>V | No | Jeffares_SNPs |
No associated diseases with Q9P7S3
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| chromatin | The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| nucleus | A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. |
| RSC-type complex | A SWI/SNF-type complex that contains a bromodomain containing-protein, such as yeast Rsc1 or Rsc4 or mammalian PB1/BAF180. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining. |
| SWI/SNF complex | A SWI/SNF-type complex that contains 8 to 14 proteins, including both conserved (core) and nonconserved components; contains the ATPase product of the yeast SNF2 or mammalian SMARCA4/BAF190A/BRG1 gene, or an ortholog thereof. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin remodeling | A dynamic process of chromatin reorganization resulting in changes to chromatin structure. These changes allow DNA metabolic processes such as transcriptional regulation, DNA recombination, DNA repair, and DNA replication. |
| double-strand break repair via nonhomologous end joining | The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear. |
| positive regulation of double-strand break repair via homologous recombination | Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination. |
| regulation of transcription by RNA polymerase II | Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSNNSRLPEN | GVQSGNGEDA | ELKKSMRIIE | REIPDSLLEK | IPEAEDYIAL | QDLERKLDSL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| IVRKRFDLQD | SLSRNSHKTR | ILRMYIHSTV | ANQSWQQKGE | NQENNSGDIN | SLPIPEWTLH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| IEGRLLVNPD | DEDDKAFELA | PFTNFFRKIA | IQILRSDDLY | PSGNYVEWNK | LPDNSNTSNG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ITVTRKGDQS | VDVKIMLYPE | EHPERYKLSK | AFANILGIRE | GTRPDIVSYL | WQYIKFHRLQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| DMEEKRLINC | DKALRDLFEA | DRLYFPRIPE | LMNRFLEPID | PIVIPYTINV | SEHTVEKVTI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FDIRINTEDP | RHSQIRSFLA | TMMSQDKIRS | IDDKLTELIQ | AITYSQSKYD | FMKKFSESPI |
| 370 | 380 | 390 | 400 | 410 | 420 |
| EFINEWIESQ | SRDLEIVLDG | TNMNYAEKRS | ADYYQQPWVH | ESAFHYLNLL | NSKKQQSVLN |
| ASAKK |