Q9P7C1

PR
Gene name
SPAC2E1P5.03
Protein name
Uncharacterized J domain-containing protein C2E1P5.03
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC2E1P5.03
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

223-303 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9P7C1

Entry ID Method Resolution Chain Position Source
AF-Q9P7C1-F1 Predicted AlphaFoldDB

4 variants for Q9P7C1

Variant ID(s) Position Change Description Diseaes Association Provenance
I_3327171_A_T 92 T>S No Jeffares_SNPs
I_3327621_G_A 242 A>T No Jeffares_SNPs
I_3327652_A_G 252 D>G No Jeffares_SNPs
I_3327661_T_C 255 M>T No Jeffares_SNPs

No associated diseases with Q9P7C1

5 regional properties for Q9P7C1

Type Name Position InterPro Accession
domain TGS 322 - 405 IPR004095
domain GTP binding domain 47 - 161 IPR006073
domain YchF, C-terminal domain 321 - 405 IPR013029
domain OBG-type guanine nucleotide-binding (G) domain 46 - 301 IPR031167
domain YchF, N-terminal 48 - 321 IPR041706

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum membrane ; Single-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
endomembrane system A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum membrane The lipid bilayer surrounding the endoplasmic reticulum.
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

1 GO annotations of molecular function

Name Definition
Hsp70 protein binding Binding to a Hsp70 protein, heat shock proteins around 70kDa in size.

1 GO annotations of biological process

Name Definition
protein folding in endoplasmic reticulum A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRIFILLLL FGVCLAWTSS DLEIFRVVDS LKSILKNKAT FYELLEVPTK ASIKEINRAY
70 80 90 100 110 120
RKKSILYHPD KNPKSKELYT LLGLIVNILR NTETRKRYDY FLKNGFPRWK GTGYLYSRYR
130 140 150 160 170 180
PGLGAVLVLL FLLISIAHFV MLVISSKRQK KIMQDHIDIA RQHESYATSA RGSKRIVQVP
190 200 210 220 230 240
GGRRIYTVDS ITGQVCILDP SSNIEYLVSP DSVASVKISD TFFYRLPRFI VWNAFGRWFA
250 260 270 280 290 300
RAPASSEDTD SDGQMEDEEK SDSVHKSSFS SPSKKEASIK AGKRRMKRRA NRIPLSKNTN
REN