Q9P735

PR
Gene name
fal-1 (8D4.050, NCU01234)
Protein name
ATP-dependent RNA helicase fal-1
Names
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU01234
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-50 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9P735

Entry ID Method Resolution Chain Position Source
AF-Q9P735-F1 Predicted AlphaFoldDB

No variants for Q9P735

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9P735

No associated diseases with Q9P735

1 regional properties for Q9P735

Type Name Position InterPro Accession
domain AMP-dependent synthetase/ligase domain 34 - 497 IPR000873

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Nucleus, nucleolus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
catalytic step 2 spliceosome A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
nucleolus A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
mRNA binding Binding to messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MADGGIDRKA DEKIQFSTSK EVTVHPTFES MSLKESLLRG IYAYGYESPS AVQSRAIVQI
70 80 90 100 110 120
CKGRDTIAQA QSGTGKTATF SISMLQVIDT AVRETQALVL SPTRELATQI QSVVMALGDY
130 140 150 160 170 180
MNVQCHACIG GTNVGEDIRK LDYGQHIVSG TPGRVADMIR RRHLRTRHIK MLVLDEADEL
190 200 210 220 230 240
LNQGFREQIY DVYRYLPPAT QVVVVSATLP YDVLDMTTKF MTDPVRILVK RDELTLEGLK
250 260 270 280 290 300
QYFIAVEKED WKFDTLCDLY DTLTITQAVI FCNTRRKVDW LTDKMREANF TVSSMHGDMP
310 320 330 340 350 360
QKERDSIMQD FRQGNSRVLI STDVWARGID VQQVSLVINY DLPSNRENYI HRIGRSGRFG
370 380 390
RKGVAINFVT SEDVRILRDI ELYYSTQIDE MPMNVADLIS