Q9P6P3

PR
Gene name
ppk15 (SPAC1E11.03, SPAC823.03)
Protein name
Serine/threonine-protein kinase ppk15
Names
Species
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
KEGG Pathway
spo:SPAC823.03
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

450-534 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

276-296 (Activation loop from InterPro)

Target domain

130-458 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q9P6P3

Entry ID Method Resolution Chain Position Source
AF-Q9P6P3-F1 Predicted AlphaFoldDB

1 variants for Q9P6P3

Variant ID(s) Position Change Description Diseaes Association Provenance
I_2587069_A_G 423 E>G No Jeffares_SNPs

No associated diseases with Q9P6P3

3 regional properties for Q9P6P3

Type Name Position InterPro Accession
domain Protein kinase domain 130 - 458 IPR000719
active_site Serine/threonine-protein kinase, active site 253 - 265 IPR008271
binding_site Protein kinase, ATP binding site 136 - 159 IPR017441

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cytoplasm
  • Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

5 GO annotations of cellular component

Name Definition
cell tip The region at the end of the longest axis of a cylindrical or elongated cell.
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
mitotic spindle pole body The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
protein tyrosine kinase activity Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.

4 GO annotations of biological process

Name Definition
peptidyl-serine phosphorylation The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
peptidyl-threonine phosphorylation The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
regulation of establishment or maintenance of cell polarity Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
signaling The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSDSPILPL SNNPPAARTH DHSQRNNHAR HVSSSGTTLF APVKPATKKY NYRRVSPHGS
70 80 90 100 110 120
YISPLEAMTV KLADTYSICN PKFQFSSEQN PRRPLTKPSE GVHNHGFDNV NHDYVLYVND
130 140 150 160 170 180
LLGTDEGRKY LILDTLGHGT FGQVARCQDL KTQQIVAIKV IKNKPAFYNQ CVMEVSILEL
190 200 210 220 230 240
LNNKYDPEDK RHLIRLYDQF MHKNHLCLVF ELLSINLYEL IKQNQFRGLH LSLVRSFATQ
250 260 270 280 290 300
LLSCTSLLKQ ARIIHCDLKP ENILLQDLSS PIVKVIDFGS ACHERQTVYT YIQSRFYRSP
310 320 330 340 350 360
EVILGLHYNC GIDMWSLGCI LAELFLGLPL FPGNSEYNQL CRIVDMLGNP PTWMLEMGKN
370 380 390 400 410 420
SKKYYNSGFV NGRKTYELKS IEQFSIENNK TEQPGKQYFG EKTLDAIVLN YPRRKTTPKL
430 440 450 460 470 480
TPEEHEERLC FIDFIKQFLE LNPLKRWTPD QAKNHPFITG ASFSQYCIDK QKPLLTTQRT
490 500 510 520 530
RNRSHTIGNQ AVVPPSLQRA STYVSNEPEE FVHTRPLPQY YPPANENENV DEFF