Q9P6K7
Gene name |
SPAC30C2.04 |
Protein name |
tRNA-aminoacylation cofactor arc1 |
Names |
|
Species |
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
KEGG Pathway |
spo:SPAC30C2.04 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9P6K7
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9P6K7-F1 | Predicted | AlphaFoldDB |
10 variants for Q9P6K7
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| I_4638193_A_C | 26 | Y>S | No | Jeffares_SNPs | |
| I_4638567_G_A | 151 | V>I | No | Jeffares_SNPs | |
| I_4638675_A_G | 187 | M>V | No | Jeffares_SNPs | |
| I_4638693_A_C | 193 | M>L | No | Jeffares_SNPs | |
| I_4638835_G_A | 240 | G>D | No | Jeffares_SNPs | |
| I_4638933_A_G | 273 | K>E | No | Jeffares_SNPs | |
| I_4638972_A_G | 286 | I>V | No | Jeffares_SNPs | |
| I_4639114_G_A | 333 | R>H | No | Jeffares_SNPs | |
| I_4639119_G_A | 335 | V>I | No | Jeffares_SNPs | |
| I_4639246_T_C | 377 | I>T | No | Jeffares_SNPs |
No associated diseases with Q9P6K7
5 regional properties for Q9P6K7
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasmic stress granule | A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. |
| eukaryotic 43S preinitiation complex | A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA. |
| methionyl glutamyl tRNA synthetase complex | A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers. |
| polysome | A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| tRNA binding | Binding to a transfer RNA. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| formation of translation preinitiation complex | The joining of the small ribosomal subunit, ternary complex, and mRNA. |
| tRNA aminoacylation for protein translation | The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA and the alpha carboxylic acid group of an amino acid, to be used in ribosome-mediated polypeptide synthesis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSFLWAKEFC | VLKYPYKLFI | THKFSYLLRF | ETVTLNNIRS | PQFYAKLTFS | HHQPTVSGTM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| STELKFISKY | LQISIPETKE | GPVSSLFKAV | SEQKPELLGN | TDFEKAQILE | WTTKAFSPIE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TQSIVEQLDE | FLKSSTFIAQ | DSGISVADLA | VYARIHSYIC | GLSAKEGYKL | NNVCRWFDFI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| QHQESVMEAA | NSMSMKLANI | DLNAPKIQRP | SVIKKDKKEK | KEGKPSQEAS | VKSVEKAPKG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LEGAKKEKQN | KKEKKDKKDK | KDKKEKAPKE | PPKAATPVPS | MIDFRIGFIE | KAVKHPNADS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LYVSTIHCGD | AEGPRTVCSG | LVKYIPLEQM | QQRKVIVVAN | LKPVNMRSVK | SQAMVFCASS |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PDKSVVEFVL | PPENAEIGDR | LTFEGFDTEE | PEAQLNPKRK | IWEAIQPGFT | SGEDLICGYK |
| 430 | 440 | ||||
| DESGLHRLFV | KGKKDLGFCK | AQTVVNGTLS |