Q9P4B9

PR
Gene name
RPB5
Protein name
DNA-directed RNA polymerases I, II, and III subunit RPABC1
Names
RNA polymerases I, II, and III subunit ABC1
Species
Kluyveromyces marxianus (Yeast) (Candida kefyr)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

25-97 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9P4B9

Entry ID Method Resolution Chain Position Source
AF-Q9P4B9-F1 Predicted AlphaFoldDB

No variants for Q9P4B9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9P4B9

No associated diseases with Q9P4B9

1 regional properties for Q9P4B9

Type Name Position InterPro Accession
conserved_site Ribosomal protein L3, conserved site 211 - 234 IPR019926

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
nuclear DNA-directed RNA polymerase complex A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.

1 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDQEQERGIS RLWRAFRTVK EMVRDRGYFI TQEEIDLSLE DFKVKYCDSM GKPQRKMMSF
70 80 90 100 110 120
QSNPTEESIE KFPEMGSLWV EFCDEASVGV KTMKNFVVHI TEKNFQTGIF IYQSGITPSA
130 140 150 160 170 180
NKILPTAAPA VIETFPEASL VVNITHHELV PKHIRLSDAE KKELLKRYRL KESQLPRIQR
190 200 210
MDPVALYLGL KRGEVIKIIR KSETSGRYAS YRICL