AiPD: Autoinhibited Protein Database

Q9NVL8

Gene name	CCDC198
Protein name	Uncharacterized protein CCDC198
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:55195
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

153-234 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

153-234 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9NVL8

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9NVL8-F1	Predicted				AlphaFoldDB

255 variants for Q9NVL8

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
CA7202083 rs756943054	2	G>V		No	ClinGen ExAC gnomAD
rs529772268 CA7202082	3	L>P		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs529772268 CA389845772	3	L>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs777561424 CA7202081	4	S>T		No	ClinGen ExAC gnomAD
rs755741754 CA7202080	5	H>L		No	ClinGen ExAC TOPMed
CA261568660 rs1018299378	6	S>P		No	ClinGen TOPMed gnomAD
rs759355354 CA7202076	9	H>Q		No	ClinGen ExAC gnomAD
rs759752791 CA7202077	9	H>Y	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs751396552 CA7202074	12	V>L		No	ClinGen ExAC gnomAD
rs751396552 CA389845670	12	V>M		No	ClinGen ExAC gnomAD
CA7202073 rs766030829	15	V>I		No	ClinGen ExAC gnomAD
CA261568608 rs985133420	16	A>V		No	ClinGen TOPMed
rs1459584440 CA389845613 COSM243294	17	P>S	prostate [Cosmic]	No	ClinGen cosmic curated TOPMed gnomAD
CA7202069 rs140776555	20	N>K		No	ClinGen ESP ExAC TOPMed gnomAD
CA7202068 rs776650696	21	K>E		No	ClinGen ExAC gnomAD
rs1385043953 CA389845462	26	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
rs201357909 CA7202064 COSM1748902	27	S>L	Variant assessed as Somatic; 0.0 impact. urinary_tract [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA261568563 rs201357909	27	S>W	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs777620715 CA7202062	28	A>P		No	ClinGen ExAC gnomAD
CA7202061 rs777620715	28	A>T		No	ClinGen ExAC gnomAD
rs755799407 CA7202060	30	R>C	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs149223383 CA7202059	30	R>H		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7202058 rs149223383	30	R>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1594830870 CA389845436	31	V>G		No	ClinGen Ensembl
rs1594830863 CA389845431	32	D>G		No	ClinGen Ensembl
rs754957433 CA7202057	35	F>C		No	ClinGen ExAC gnomAD
CA389845406 rs555016984	36	N>H		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA261568482 rs1055486668	36	N>S		No	ClinGen TOPMed gnomAD
CA7202056 rs555016984	36	N>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA389845398 rs1244002468	37	Q>*		No	ClinGen TOPMed gnomAD
CA389845388 rs1386299135	38	N>S		No	ClinGen TOPMed
rs1474803734 CA389845375	40	E>*		No	ClinGen gnomAD
TCGA novel	40	E>A	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA261568466 rs903828799	41	E>K		No	ClinGen TOPMed
CA7202053 rs146627831	43	T>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1447353445 CA389845344	44	S>L		No	ClinGen gnomAD
rs1042383005 CA261568450	45	Y>C		No	ClinGen TOPMed
rs765473482 CA7202052	46	S>A		No	ClinGen ExAC gnomAD
CA389845309 rs1594830619	49	R>G		No	ClinGen Ensembl
rs761973982 CA7202050	49	R>K		No	ClinGen ExAC gnomAD
rs1386415061 CA389845271	51	Q>R		No	ClinGen TOPMed
CA389845249 rs1272128560	52	D>E		No	ClinGen gnomAD
CA389845237 rs1431816495	53	Q>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA389845217 rs1330857474	55	K>I		No	ClinGen gnomAD
rs1301639178 CA389845216	55	K>N		No	ClinGen gnomAD
CA389845212 rs1299550896	56	A>S		No	ClinGen TOPMed
CA389845172 rs1168515573	62	P>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA389845163 rs1416845823	63	P>L		No	ClinGen gnomAD
CA389845166 rs1408861592	63	P>S		No	ClinGen TOPMed gnomAD
CA7202047 rs760800498	68	W>*		No	ClinGen ExAC
rs547387205 CA7202046	71	R>K		No	ClinGen 1000Genomes ExAC gnomAD
CA389845103 rs1229333302	72	Y>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed
CA261568391 rs796157180	73	S>P		No	ClinGen Ensembl
CA7202045 rs144484702	74	T>A		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA261568389 rs144484702	74	T>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1422314071 CA389844649	77	R>G		No	ClinGen TOPMed gnomAD
CA389844617 rs1371810597	78	D>E		No	ClinGen TOPMed
CA7202034 rs764950635	80	Y>H		No	ClinGen ExAC TOPMed gnomAD
CA7202032 rs754074506	81	F>V		No	ClinGen ExAC gnomAD
TCGA novel	82	D>E	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs764363010 CA7202031	83	I>N		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	83	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA261566293 rs200269990	84	P>Q		No	ClinGen Ensembl
TCGA novel	86	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs544713609 CA389844443	89	E>A		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7202030 rs544713609 COSM3744385	89	E>G	liver [Cosmic]	No	ClinGen cosmic curated 1000Genomes ExAC TOPMed gnomAD
TCGA novel	89	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389844449 rs1269390866	89	E>Q		No	ClinGen gnomAD
CA7202028 rs775611100	90	T>I		No	ClinGen ExAC TOPMed gnomAD
CA7202027 rs768171895	93	I>F		No	ClinGen ExAC TOPMed gnomAD
rs760072259 CA7202026	95	R>K		No	ClinGen ExAC gnomAD
rs938615075 CA389844343	95	R>S		No	ClinGen TOPMed gnomAD
CA389844333 rs1324690511	96	H>Y		No	ClinGen gnomAD
CA7202025 rs774869771	97	P>L		No	ClinGen ExAC gnomAD
rs1293230516 CA389844294	98	P>L		No	ClinGen TOPMed
rs145357859 CA7201988	105	E>D		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1566584241 CA389843444	106	P>S		No	ClinGen Ensembl
rs146784735 CA7201987	107	I>M		No	ClinGen ESP ExAC TOPMed gnomAD
rs765567833 CA7201985	108	D>N		No	ClinGen ExAC TOPMed gnomAD
CA389843421 rs1383254051	109	L>F		No	ClinGen TOPMed
rs1566584184 CA389843425	109	L>S		No	ClinGen Ensembl
COSM3814973 CA7201983 rs775180996	110	P>Q	Variant assessed as Somatic; 0.0 impact. breast [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs149798976 CA7201982	111	R>*		No	ClinGen ESP ExAC TOPMed gnomAD
rs759085921 CA7201981	111	R>Q		No	ClinGen ExAC gnomAD
rs1425364711 CA389843405	112	V>I		No	ClinGen gnomAD
CA7201980 rs139733112	113	I>T		No	ClinGen ESP ExAC TOPMed gnomAD
CA7201979 rs770797743	114	T>N		No	ClinGen ExAC TOPMed gnomAD
rs1168557535 CA389843373	114	T>P		No	ClinGen gnomAD
rs777436221 CA7201977	116	G>E	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
rs1038816791 CA261559318	118	L>V		No	ClinGen Ensembl
CA7201976 rs150566449	121	Q>H		No	ClinGen ESP ExAC TOPMed gnomAD
COSM3401363 rs747886419 CA7201975	122	R>*	central_nervous_system [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed gnomAD
CA7201974 rs562072722	122	R>Q		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs910036148 CA261559291	123	E>D		No	ClinGen TOPMed
TCGA novel	124	A>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	125	R>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs755222944 CA389843206	125	R>S		No	ClinGen ExAC gnomAD
rs751722948 CA7201972	126	T>I		No	ClinGen ExAC gnomAD
CA389843197 rs1485853962	126	T>S		No	ClinGen Ensembl
rs367641569 CA7201970	128	H>P		No	ClinGen ESP ExAC TOPMed gnomAD
rs1304850787 CA389843121	130	A>G		No	ClinGen gnomAD
rs780131468 CA7201954	132	Q>*		No	ClinGen ExAC gnomAD
rs201110545 CA7201952	133	V>A		No	ClinGen ExAC gnomAD
CA7201951 rs201110545	133	V>G		No	ClinGen ExAC gnomAD
rs758559120 CA389842912	133	V>I		No	ClinGen ExAC gnomAD
CA7201953 rs758559120	133	V>L		No	ClinGen ExAC gnomAD
CA389842837 rs1288657920	137	K>T		No	ClinGen Ensembl
CA389842828 rs888396502	138	M>K		No	ClinGen TOPMed gnomAD
CA261557982 rs888396502	138	M>T		No	ClinGen TOPMed gnomAD
CA7201947 rs754631919	141	P>L		No	ClinGen ExAC gnomAD
rs1314421690 CA389842799	142	M>T		No	ClinGen gnomAD
CA389842803 rs1377701624	142	M>V		No	ClinGen TOPMed gnomAD
CA7201946 rs751281239	143	Y>H		No	ClinGen ExAC gnomAD
CA7201945 rs765934485	144	T>A	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA gnomAD
rs866408699 CA261557974	146	E>K		No	ClinGen Ensembl
CA261557971 rs1025090564	148	R>*		No	ClinGen TOPMed
rs765255007 CA7201942	150	Y>C		No	ClinGen ExAC gnomAD
rs772568923 CA7201943	150	Y>H		No	ClinGen ExAC TOPMed gnomAD
rs1445386275 CA389842726	153	K>E		No	ClinGen gnomAD
rs1566581668 CA389842720	153	K>N		No	ClinGen Ensembl
rs1385179492 CA389842703	154	M>I		No	ClinGen gnomAD
CA261557914 rs776568475	154	M>R		No	ClinGen ExAC gnomAD
COSM698294 CA7201940 rs776568475	154	M>T	lung Variant assessed as Somatic; 0.0 impact. [Cosmic, NCI-TCGA]	No	ClinGen cosmic curated ExAC NCI-TCGA gnomAD
rs201234958 CA261557909	156	V>G		No	ClinGen 1000Genomes gnomAD
CA389842687 rs1182376803	156	V>L		No	ClinGen gnomAD
rs1187892581 CA389842680	157	L>P		No	ClinGen TOPMed gnomAD
CA7201938 rs35977877	159	M>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs775826016 CA7201937	160	I>S		No	ClinGen ExAC gnomAD
rs189684969 CA7201936	161	R>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA7201935 rs745990428	161	R>H		No	ClinGen ExAC TOPMed gnomAD
CA7201934 rs778808490	162	K>R		No	ClinGen ExAC gnomAD
TCGA novel	163	R>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389842625 rs1281850518	165	E>D		No	ClinGen gnomAD
CA389842628 rs1466818775	165	E>G		No	ClinGen Ensembl
rs749730596 CA7201931	165	E>K		No	ClinGen ExAC gnomAD
rs767646481 CA7201911	166	A>D		No	ClinGen ExAC TOPMed gnomAD
CA7201912 rs112954258	166	A>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1489394903 CA389842575	171	K>E		No	ClinGen gnomAD
rs889472185 CA261556886	171	K>R		No	ClinGen TOPMed
CA389842532 rs1419912110	177	E>Q	Variant assessed as Somatic; impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
rs1436217128 CA389842521	178	A>E		No	ClinGen gnomAD
CA389842508 rs1377544408	180	I>N		No	ClinGen TOPMed
TCGA novel	180	I>S	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs34960436 CA7201906 RCV000238939	183	Q>*		No	ClinGen ClinVar 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs750106322 CA7201905	183	Q>H		No	ClinGen ExAC gnomAD
CA261556826 rs961009606	185	P>S		No	ClinGen TOPMed
rs961009606 CA389842473	185	P>T		No	ClinGen TOPMed
rs1266438094 CA389842467	186	R>K		No	ClinGen TOPMed
rs1488322196 CA389842453	188	H>D		No	ClinGen TOPMed
CA7201901 rs34786761	188	H>Q		No	ClinGen ESP ExAC TOPMed gnomAD
CA261556814 rs751857460	189	K>I		No	ClinGen TOPMed gnomAD
rs752549069 CA7201899	191	K>R		No	ClinGen ExAC gnomAD
rs1465779937 CA389842420	192	K>N		No	ClinGen gnomAD
CA389842401 rs1247499310	195	Q>H		No	ClinGen TOPMed gnomAD
CA389842396 rs1404922793	196	S>I		No	ClinGen gnomAD
CA7201896 rs774495205	198	P>R		No	ClinGen ExAC gnomAD
CA261556779 rs759817234	199	R>K		No	ClinGen Ensembl
CA7201894 rs771120243	200	N>D		No	ClinGen ExAC gnomAD
rs763063809 CA7201893	202	D>E		No	ClinGen ExAC TOPMed
CA261556763 rs369138268	202	D>N		No	ClinGen ESP TOPMed gnomAD
rs1261517699 CA389842304	204	D>E		No	ClinGen gnomAD
rs770310584 CA7201891	204	D>N		No	ClinGen ExAC
rs748549020 CA7201890	204	D>V		No	ClinGen ExAC gnomAD
rs1212608075 CA389842298	205	L>I		No	ClinGen gnomAD
CA389842279 rs1456140600	206	L>V		No	ClinGen TOPMed
CA389842261 rs1333117556	207	T>N		No	ClinGen TOPMed
CA261556742 rs1056812053	208	M>T		No	ClinGen TOPMed
CA261556747 rs1028616938	208	M>V		No	ClinGen Ensembl
rs1445929560 CA389842216	210	P>T		No	ClinGen TOPMed
rs781718635 CA7201888	211	D>G		No	ClinGen ExAC gnomAD
CA389842168 rs1222599611	212	E>D		No	ClinGen gnomAD
CA7201886 rs747373215	215	N>K		No	ClinGen ExAC TOPMed gnomAD
rs149520479 CA7201885	217	G>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs748829551 CA7201883	218	P>L		No	ClinGen ExAC
rs1485926698 CA389840665	219	G>E		No	ClinGen TOPMed gnomAD
CA7201881 rs563276311	219	G>R	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen 1000Genomes ExAC NCI-TCGA TOPMed gnomAD
CA7201819 rs776014232	222	K>E		No	ClinGen ExAC TOPMed gnomAD
rs1351167088 CA389840623	225	E>A		No	ClinGen gnomAD
CA7201818 CA7201817 rs777948627	225	E>D		No	ClinGen ExAC TOPMed gnomAD
rs1433662513 CA389840626	225	E>K		No	ClinGen gnomAD
CA7201814 rs137965995	227	L>F		No	ClinGen ESP ExAC TOPMed gnomAD
CA7201813 rs771954185	228	K>N		No	ClinGen ExAC gnomAD
rs745681639 CA7201812	229	H>Q		No	ClinGen ExAC gnomAD
rs1172484397 CA389840596	229	H>R		No	ClinGen gnomAD
CA7201811 rs757423243	230	Q>L		No	ClinGen ExAC gnomAD
CA7201810 rs757423243	230	Q>R		No	ClinGen ExAC gnomAD
CA389840577 rs1194193011	232	V>A		No	ClinGen TOPMed
rs1189449784 CA389840566	234	N>D		No	ClinGen gnomAD
VAR_024310 rs1152530 CA7201809	235	Y>C		No	ClinGen UniProt 1000Genomes ESP ExAC TOPMed dbSNP gnomAD
rs1152530 CA389840555	235	Y>F		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs1152530 CA389840556	235	Y>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA261549756 rs375624300	236	C>G		No	ClinGen ESP ExAC TOPMed
rs375624300 CA7201808	236	C>R		No	ClinGen ESP ExAC TOPMed
CA7201807 rs756311833	236	C>S		No	ClinGen ExAC gnomAD
CA389840545 rs1178126362	237	P>S		No	ClinGen gnomAD
CA7201806 CA389840541 rs369678249	238	W>R		No	ClinGen ESP ExAC TOPMed gnomAD
CA7201805 rs141059426	240	I>T		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs760072327 CA7201804	241	G>D		No	ClinGen ExAC gnomAD
CA389840499 rs1312040276	241	G>S		No	ClinGen gnomAD
CA389840486 rs1221475870	242	K>*		No	ClinGen gnomAD
TCGA novel	243	M>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389840468 rs1368958674	243	M>T		No	ClinGen gnomAD
CA261549699 rs201420652	246	W>C		No	ClinGen 1000Genomes gnomAD
rs369248135 CA7201803	246	W>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs1374191015 CA389840410	247	L>F		No	ClinGen gnomAD
CA389840407 rs1225094376	247	L>P		No	ClinGen gnomAD
rs202244661 CA7201801	248	H>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs146602887 CA7201802 COSM1707380	248	H>Y	Variant assessed as Somatic; 0.0 impact. skin [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA TOPMed gnomAD
CA389840337 rs1370839572	252	A>G		No	ClinGen TOPMed
rs776407104 CA7201800	252	A>S		No	ClinGen ExAC TOPMed gnomAD
rs776407104 CA389840345	252	A>T		No	ClinGen ExAC TOPMed gnomAD
rs755772802 CA261549686	254	G>*		No	ClinGen Ensembl
rs768263330 CA7201799	255	Q>L		No	ClinGen ExAC
rs984274565 CA261549676	256	L>P		No	ClinGen Ensembl
TCGA novel	257	L>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA389840259 rs200420976	259	D>N		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs200420976 CA7201798	259	D>Y		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs774929547 COSM401485 CA7201797	260	S>C	lung [Cosmic]	No	ClinGen cosmic curated ExAC gnomAD
rs1158053136 CA389840236	260	S>N		No	ClinGen gnomAD
CA261549668 rs1025979974	261	S>P		No	ClinGen Ensembl
rs1437980878 CA389840212	262	S>N		No	ClinGen gnomAD
rs993131070 CA261549648	264	D>H		No	ClinGen Ensembl
CA261549634 rs571261292	265	S>P		No	ClinGen Ensembl
CA389840139 rs1483112021	267	E>D		No	ClinGen TOPMed gnomAD
rs181050215 CA7201795	267	E>K		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs774148887 CA7201794	268	Q>P		No	ClinGen ExAC gnomAD
rs774148887 CA389840132	268	Q>R		No	ClinGen ExAC gnomAD
CA389840121 rs1173466856	269	G>R		No	ClinGen Ensembl
CA7201792 rs749013253	271	D>Y		No	ClinGen ExAC gnomAD
CA7201791 rs778097592	274	K>R		No	ClinGen ExAC TOPMed gnomAD
CA389840043 rs778097592	274	K>T		No	ClinGen ExAC TOPMed gnomAD
rs144453893 CA7201789	276	R>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs748261627 CA389840020	276	R>L		No	ClinGen ExAC TOPMed gnomAD
CA7201788 rs748261627	276	R>Q		No	ClinGen ExAC TOPMed gnomAD
CA389840014 rs1378017201	277	A>G		No	ClinGen gnomAD
CA7201787 rs781366514	277	A>T		No	ClinGen ExAC gnomAD
rs1152531 CA389839980	280	R>S		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs367897577 CA261549519	282	R>G		No	ClinGen ESP
rs758833561 CA7201783	282	R>K		No	ClinGen ExAC
CA389839937 rs1464831327	284	E>K		No	ClinGen gnomAD
TCGA novel	284	E>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1052487725 CA261549484	286	I>V		No	ClinGen Ensembl
CA389839890 rs1423417431	287	P>L		No	ClinGen gnomAD
CA7201777 rs760259322	288	L>F		No	ClinGen ExAC gnomAD
CA389839851 rs1489572855	290	D>E		No	ClinGen gnomAD
CA389839856 rs1197754042	290	D>G		No	ClinGen gnomAD
CA7201775 rs200992969	290	D>N		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs201407662 CA7201773	291	E>*		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7201774 rs201407662	291	E>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA7201771 rs749139861	292	F>L		No	ClinGen ExAC TOPMed gnomAD
CA389839829 rs1310220128	292	F>Y		No	ClinGen gnomAD
rs948316316 CA261549427	293	F>L		No	ClinGen Ensembl
CA389839804 rs1566567390	294	D>Y		No	ClinGen Ensembl
CA7201769 rs773095015	295	Q>R		No	ClinGen ExAC gnomAD
rs770154918 CA7201768	296	E>K		No	ClinGen ExAC gnomAD

No associated diseases with Q9NVL8

No regional properties for Q9NVL8

Type	Name	Position	InterPro Accession
No domain, repeats, and functional sites for Q9NVL8

Functions

		Description
EC Number
Subcellular Localization	Cell membrane ; Peripheral membrane protein Cytoplasmic vesicle	The localization of CCDC198 changes from membranous to vesicle-forming structures in the malignant tissue
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

No GO annotations of cellular component

Name	Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name	Definition
No GO annotations for molecular function

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MGLSHSKTHL	RVIKVAPLQN	KEVETPSAGR	VDFAFNQNLE	EKTSYSLARL	QDQNKALEGQ
70	80	90	100	110	120
LPPLQENWYG	RYSTASRDMY	FDIPLEHRET	SIIKRHPPQR	LQKLEPIDLP	RVITSGRLLS
130	140	150	160	170	180
QREARTMHKA	KQVLEKKMQT	PMYTSENRQY	LHKMQVLEMI	RKRQEAQMEL	KKSLHGEARI
190	200	210	220	230	240
NKQSPRDHKA	KKTLQSTPRN	DDHDLLTMLP	DEILNRGPGN	SKNTEFLKHQ	AVNNYCPWKI
250	260	270	280	290
GKMETWLHEQ	EAQGQLLWDS	SSSDSDEQGK	DEKKPRALVR	TRTERIPLFD	EFFDQE