AiPD: Autoinhibited Protein Database

Q9NU53

Gene name	GINM1 (C6orf72, UNQ710/PRO1361)
Protein name	Glycoprotein integral membrane protein 1
Names
Species	Homo sapiens (Human)
KEGG Pathway	hsa:116254
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain
Relief mechanism
Assay	cis-regPred

AID

1-69 (Predicted disordered autoinhibitory region)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Yeon JH et al. (2016) "Systems-wide Identification of cis-Regulatory Elements in Proteins", Cell Systems, 2, 89-100

Autoinhibited structure

Activated structure

1 structures for Q9NU53

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9NU53-F1	Predicted				AlphaFoldDB

237 variants for Q9NU53

Variant ID(s)	Position	Change	Description	Diseaes Association	Provenance
rs745626953 CA4042587	3	G>D		No	ClinGen ExAC gnomAD
CA4042586 rs780954745	3	G>S		No	ClinGen ExAC TOPMed gnomAD
CA366009515 rs1285112911	4	A>T		No	ClinGen gnomAD
rs769668787 CA4042588	6	P>L		No	ClinGen ExAC TOPMed gnomAD
rs562448511 CA4042590	7	G>V		No	ClinGen 1000Genomes ExAC gnomAD
CA366009540 rs1210648307	8	S>L		No	ClinGen TOPMed gnomAD
rs774501814 CA4042592	10	A>P		No	ClinGen ExAC TOPMed gnomAD
rs774501814 CA366009548	10	A>S		No	ClinGen ExAC TOPMed gnomAD
rs762047324 CA4042593	11	L>F		No	ClinGen ExAC TOPMed gnomAD
CA366009587 rs977719157	17	V>L		No	ClinGen TOPMed gnomAD
rs977719157 CA149955454	17	V>M	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA TOPMed gnomAD
CA4042597 rs766718765	18	A>V		No	ClinGen ExAC gnomAD
CA149955478 rs754216692	20	P>L		No	ClinGen ExAC TOPMed gnomAD
CA4042598 rs754216692	20	P>R		No	ClinGen ExAC TOPMed gnomAD
CA366009621 rs1293113391	23	G>D		No	ClinGen gnomAD
CA149955483 rs955280445	23	G>S		No	ClinGen TOPMed
rs755411796 CA366009628	24	W>*		No	ClinGen ExAC TOPMed gnomAD
CA366009625 rs1351289320	24	W>*		No	ClinGen gnomAD
rs755411796 CA4042599	24	W>C		No	ClinGen ExAC TOPMed gnomAD
CA149955501 rs911057726	26	T>A		No	ClinGen TOPMed gnomAD
rs997881466 CA149955504	26	T>M		No	ClinGen Ensembl
rs1562268775 CA366009647	28	G>S		No	ClinGen Ensembl
CA4042603 rs780676050	30	P>A		No	ClinGen ExAC gnomAD
CA4042604 rs532883672	30	P>L		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA366009658 rs780676050	30	P>S		No	ClinGen ExAC gnomAD
CA4042606 rs779837750	32	P>L		No	ClinGen ExAC TOPMed gnomAD
CA366009685 rs1183901292	34	P>L		No	ClinGen gnomAD
CA149955553 rs969328527	36	S>F		No	ClinGen Ensembl
CA149955560 rs978848016	37	G>E		No	ClinGen TOPMed gnomAD
CA366009696 rs1172698002	37	G>R		No	ClinGen gnomAD
rs774483236 CA4042609	38	A>T		No	ClinGen ExAC TOPMed gnomAD
rs1031743815 CA149955569	38	A>V		No	ClinGen TOPMed gnomAD
rs1428957383 CA366009709	39	P>R		No	ClinGen TOPMed
rs1368630088 CA366009713	40	Q>*		No	ClinGen TOPMed
CA4042610 rs761957253	40	Q>R		No	ClinGen ExAC TOPMed gnomAD
CA365999486 rs1302570398	41	D>G		No	ClinGen gnomAD
CA4042627 rs754864124	42	G>D		No	ClinGen ExAC TOPMed gnomAD
CA4042625 rs142853295	42	G>R		No	ClinGen ESP ExAC gnomAD
COSM1074430 rs142853295 CA4042626	42	G>S	Variant assessed as Somatic; 4.667e-05 impact. endometrium [NCI-TCGA, Cosmic]	No	ClinGen cosmic curated ESP ExAC NCI-TCGA gnomAD
CA365999545 rs1273920970	45	I>M		No	ClinGen gnomAD
CA4042628 rs199901540	48	T>I		No	ClinGen ESP ExAC TOPMed gnomAD
CA4042629 rs748052857	49	T>I		No	ClinGen ExAC gnomAD
rs771917817 CA4042630	53	D>G		No	ClinGen ExAC gnomAD
CA365999651 rs1485179756	55	D>Y		No	ClinGen TOPMed
rs747124651 CA149908132	56	I>L		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	56	I>T	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4042632 rs747124651	56	I>V		No	ClinGen ExAC TOPMed gnomAD
rs771172096 COSM421040 CA4042633	57	S>P	urinary_tract [Cosmic]	No	ClinGen cosmic curated ExAC TOPMed
rs1278918911 CA365999681	58	K>E		No	ClinGen TOPMed
rs776886244 CA4042634	60	Q>*		No	ClinGen ExAC gnomAD
rs1562270336 CA365999719	60	Q>H		No	ClinGen Ensembl
CA4042648 rs758354098	62	V>I		No	ClinGen ExAC gnomAD
CA4042649 rs777630061	63	L>F		No	ClinGen ExAC TOPMed gnomAD
rs1417958067 CA365999872	64	N>D		No	ClinGen TOPMed gnomAD
CA365999927 rs1287037295	67	Y>H		No	ClinGen gnomAD
TCGA novel	68	E>G	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1314663881 CA365999982	70	G>E		No	ClinGen gnomAD
rs1396365007 CA365999978	70	G>R		No	ClinGen gnomAD
CA4042654 rs373801091	75	N>S	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
rs770015787 CA4042655	76	D>N		No	ClinGen ExAC gnomAD
CA4042657 rs763289534	78	P>A		No	ClinGen ExAC gnomAD
CA366000106 rs1202492778	78	P>L		No	ClinGen gnomAD
CA366000156 rs1485430253	82	G>V		No	ClinGen gnomAD
CA4042658 rs541056398	83	V>A		No	ClinGen 1000Genomes ExAC gnomAD
rs774766879 CA4042659	84	T>N		No	ClinGen ExAC TOPMed gnomAD
rs762417430 CA4042660	85	R>*		No	ClinGen ExAC gnomAD
CA4042661 rs761125598	85	R>Q		No	ClinGen ExAC gnomAD
rs753416345 CA4042662	86	I>R		No	ClinGen ExAC TOPMed gnomAD
CA366000206 rs1469745270	87	S>N		No	ClinGen TOPMed
rs765049479 CA4042664	88	C>R		No	ClinGen ExAC gnomAD
rs1414398575 CA366000243	91	L>S		No	ClinGen gnomAD
rs1554219254 COSM1545115 CA4042665	93	V>L	lung [Cosmic]	No	ClinGen cosmic curated Ensembl
CA366001091 rs1277245329	94	K>*		No	ClinGen gnomAD
rs1582735473 CA366001104	95	N>I		No	ClinGen Ensembl
TCGA novel	97	N>H	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366001119 rs1192687017	97	N>S		No	ClinGen TOPMed
rs1266046835 CA366001162	103	E>*		No	ClinGen gnomAD
rs759175308 CA4042692	103	E>V		No	ClinGen ExAC gnomAD
TCGA novel	104	K>N	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs764963346 CA4042693	105	E>*		No	ClinGen ExAC TOPMed gnomAD
CA4042695 rs145071660	109	I>V		No	ClinGen ESP ExAC TOPMed gnomAD
CA366001246 rs1429074272	115	L>*		No	ClinGen gnomAD
rs1172358563 CA366001250	115	L>F		No	ClinGen gnomAD
rs763745277 CA4042696	116	V>G		No	ClinGen ExAC gnomAD
CA366001259 rs1421397494	117	H>R		No	ClinGen gnomAD
rs200356862 CA4042698	119	W>*		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs200356862 CA4042699	119	W>C		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA4042697 rs148558124	119	W>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs557030904 CA149912578	120	P>L		No	ClinGen Ensembl
CA149912605 rs938916757	121	M>T		No	ClinGen TOPMed
rs750484367 CA4042700	121	M>V		No	ClinGen ExAC TOPMed gnomAD
rs756233383 CA4042702	124	G>C		No	ClinGen ExAC gnomAD
rs756233383 CA4042701	124	G>R		No	ClinGen ExAC gnomAD
rs867547443 CA149912635	125	S>F		No	ClinGen Ensembl
rs1394332421 CA366001359	126	S>G		No	ClinGen gnomAD
rs779084458 CA4042705	133	Q>E		No	ClinGen ExAC gnomAD
CA4042706 rs748594378	135	E>A		No	ClinGen ExAC gnomAD
CA366001570 rs748594378	135	E>V		No	ClinGen ExAC gnomAD
CA4042708 rs772693938	137	V>A		No	ClinGen ExAC TOPMed gnomAD
CA4042707 rs772693938	137	V>G		No	ClinGen ExAC TOPMed gnomAD
TCGA novel	138	E>D	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs745341969 CA4042709	141	G>E		No	ClinGen ExAC gnomAD
CA366001739 rs1467925237	143	Q>H		No	ClinGen TOPMed gnomAD
CA149912707 rs947800767	143	Q>K		No	ClinGen TOPMed
rs993902305 CA149913289	144	V>A		No	ClinGen Ensembl
CA4042729 rs372765071	145	Q>R		No	ClinGen ESP ExAC gnomAD
rs1214743537 CA366002634	148	D>E		No	ClinGen gnomAD
rs747468426 CA4042730	149	V>I		No	ClinGen ExAC TOPMed gnomAD
rs1185368495 CA366002659	152	I>T		No	ClinGen gnomAD
TCGA novel	152	I>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs148645680 CA4042732	153	D>V		No	ClinGen ESP ExAC TOPMed gnomAD
rs1582735900 CA366002681	155	L>F		No	ClinGen Ensembl
rs78098524 CA4042733	156	V>I		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA4042734 rs78098524	156	V>L		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs202099709 CA4042735	159	R>Q		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA149913311 rs896003323	159	R>W		No	ClinGen TOPMed gnomAD
rs1582735914 CA366002709	160	G>A		No	ClinGen Ensembl
CA4042736 rs761563128	160	G>R		No	ClinGen ExAC gnomAD
rs965002666 CA149913323	161	V>A		No	ClinGen Ensembl
rs1282877905 CA366002728	163	R>S		No	ClinGen TOPMed gnomAD
rs1413384215 CA366002742	165	S>L		No	ClinGen gnomAD
rs1351377618 CA366002745	166	N>Y		No	ClinGen gnomAD
rs1444433787 CA366002755	167	Y>C		No	ClinGen TOPMed gnomAD
CA366002764 rs1400964686	168	T>I		No	ClinGen TOPMed
CA149913345 rs1023533034	169	L>P		No	ClinGen TOPMed
rs775212681 CA4042740	170	P>R		No	ClinGen ExAC gnomAD
rs375497080 CA4042739	170	P>S		No	ClinGen ESP ExAC TOPMed gnomAD
rs1223147089 CA366002799	174	S>G		No	ClinGen gnomAD
rs1562272226 CA366002807	175	M>V		No	ClinGen Ensembl
TCGA novel	176	L>F	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
TCGA novel	176	L>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA149913379 rs753886714	178	S>P		No	ClinGen TOPMed gnomAD
CA4042742 rs564649407	179	I>V	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ExAC NCI-TCGA TOPMed gnomAD
CA4042743 rs373895852	181	R>*		No	ClinGen ExAC gnomAD
CA366002846 rs1183286450	181	R>Q		No	ClinGen gnomAD
rs752928540 CA4042744	182	D>N		No	ClinGen ExAC gnomAD
rs1187206442 CA366002858	183	S>G		No	ClinGen TOPMed
rs758714565 CA4042745	183	S>N		No	ClinGen ExAC gnomAD
CA149913397 rs1000417578	184	D>V		No	ClinGen TOPMed
CA4042746 rs568589964	185	I>V		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
rs747382393 CA4042748	188	T>I		No	ClinGen ExAC gnomAD
CA4042747 rs747382393	188	T>N		No	ClinGen ExAC gnomAD
CA149913422 rs957437135	189	L>P		No	ClinGen Ensembl
CA366002960 rs1187747354	192	L>I		No	ClinGen gnomAD
CA149913481 rs988930993	194	K>N		No	ClinGen gnomAD
rs1411894477 CA366003009	194	K>R		No	ClinGen gnomAD
TCGA novel	196	E>K	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4042769 rs781517162	199	S>I		No	ClinGen ExAC TOPMed gnomAD
CA366003197 rs1326818506	200	S>L		No	ClinGen gnomAD
TCGA novel	200	S>P	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4042770 rs750899252	204	T>I		No	ClinGen ExAC TOPMed gnomAD
rs113405611 CA149913788	206	Q>*		No	ClinGen Ensembl
rs568421688 CA4042771	206	Q>R		No	ClinGen 1000Genomes ExAC TOPMed gnomAD
CA4042773 rs747726414	207	Y>C		No	ClinGen ExAC gnomAD
CA4042774 rs771702613	209	I>T		No	ClinGen ExAC TOPMed gnomAD
rs777455778 CA4042775	210	R>G		No	ClinGen ExAC gnomAD
rs1562272396 CA366003354	213	E>K		No	ClinGen Ensembl
TCGA novel	215	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366003413 rs1582736317	218	E>K		No	ClinGen Ensembl
TCGA novel	221	L>Y	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA4042777 rs151291405	223	G>R		No	ClinGen ESP ExAC
CA366003469 rs1351916019	224	K>E		No	ClinGen TOPMed gnomAD
rs759458853 CA4042779	231	R>K		No	ClinGen ExAC gnomAD
rs1463109159 CA366003533	232	A>E		No	ClinGen TOPMed
CA4042781 rs775706393	233	E>G		No	ClinGen ExAC gnomAD
CA4042782 rs763183200	234	P>L		No	ClinGen ExAC TOPMed gnomAD
rs1325133603 CA366003590	236	S>F		No	ClinGen TOPMed gnomAD
rs751844499 CA4042784	237	S>L		No	ClinGen ExAC TOPMed gnomAD
rs1383681828 CA366003620	239	K>E		No	ClinGen gnomAD
CA366004047 rs1479693745	243	Q>H		No	ClinGen gnomAD
CA149915180 rs1054260366	244	W>C		No	ClinGen TOPMed
rs140562734 CA4042812	244	W>G		No	ClinGen ESP ExAC TOPMed gnomAD
rs756928537 CA4042813	245	M>T		No	ClinGen ExAC gnomAD
rs780764319 CA4042814	246	E>G		No	ClinGen ExAC gnomAD
CA4042815 rs1137086	247	K>E		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
CA366004210 rs1284383626	250	K>E		No	ClinGen TOPMed
rs1446868688 CA366004264	251	D>E		No	ClinGen TOPMed
CA366004244 rs756008447	251	D>H		No	ClinGen ExAC gnomAD
CA4042816 rs756008447	251	D>N		No	ClinGen ExAC gnomAD
rs1460005370 CA366004322	255	F>S		No	ClinGen gnomAD
CA366004341 rs1582737038	256	W>*		No	ClinGen Ensembl
rs1330120127 CA366004352	256	W>*	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen NCI-TCGA gnomAD
CA4042817 rs780022994	257	S>N		No	ClinGen ExAC TOPMed gnomAD
CA149915215 rs763195989	258	N>S		No	ClinGen Ensembl
CA4042819 rs369466491	259	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA366004445 rs1406808090	260	F>L		No	ClinGen TOPMed
CA366004449 rs1406808090	260	F>V		No	ClinGen TOPMed
CA4042820 rs774486657	260	F>Y		No	ClinGen ExAC gnomAD
CA4042821 rs748236590	262	V>L		No	ClinGen ExAC TOPMed gnomAD
CA149915285 rs998033226	264	F>L		No	ClinGen TOPMed
rs61740595 CA149915324	268	N>T		No	ClinGen Ensembl
CA4042825 rs760917588	270	M>I		No	ClinGen ExAC gnomAD
CA4042824 rs773349705	270	M>V		No	ClinGen ExAC gnomAD
rs577606517 CA149915380	271	V>M		No	ClinGen 1000Genomes
TCGA novel	273	G>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366004822 rs1250176339	275	T>I		No	ClinGen TOPMed
TCGA novel	276	G>*	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs766681110 CA366004830 CA4042826	276	G>R		No	ClinGen ExAC gnomAD
rs1488032695 CA366004858	277	A>E		No	ClinGen gnomAD
CA149915403 rs776994605	280	V>I		No	ClinGen ExAC TOPMed gnomAD
rs776994605 CA4042827	280	V>L		No	ClinGen ExAC TOPMed gnomAD
CA366004922 rs1582737112	281	I>V		No	ClinGen Ensembl
CA4042828 rs533765799	282	T>I		No	ClinGen 1000Genomes ExAC gnomAD
rs1289590485 CA366004960	283	I>N		No	ClinGen TOPMed
CA366004955 rs1322646109	283	I>V		No	ClinGen TOPMed
TCGA novel	284	L>V	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
CA366004993 rs1244289650	285	K>E		No	ClinGen TOPMed
CA366005017 rs1356821011	286	V>G		No	ClinGen TOPMed
CA149915431 rs751065479	286	V>L		No	ClinGen ExAC
rs751065479 CA4042830	286	V>M		No	ClinGen ExAC
rs1324462711 CA366005090	291	S>T		No	ClinGen gnomAD
CA366005122 rs1349846296	292	E>D		No	ClinGen gnomAD
CA149915495 rs984943233	293	Y>H		No	ClinGen TOPMed
CA366006740 rs1313710024	298	Q>*		No	ClinGen gnomAD
rs775901745 CA366006753	299	L>V		No	ClinGen ExAC TOPMed gnomAD
CA4042851 rs763543253	302	V>M		No	ClinGen ExAC gnomAD
CA4042854 rs141208211	304	V>D		No	ClinGen ESP ExAC gnomAD
CA4042853 rs376204256	304	V>I	Variant assessed as Somatic; 0.0 impact. [NCI-TCGA]	No	ClinGen ESP ExAC NCI-TCGA TOPMed gnomAD
CA4042855 rs766194984	305	I>L		No	ClinGen ExAC TOPMed gnomAD
rs73781243 CA4042857	306	P>R		No	ClinGen 1000Genomes ESP ExAC TOPMed gnomAD
rs753666762 CA4042856	306	P>S		No	ClinGen ExAC gnomAD
rs1280566672 CA366006838	307	V>M		No	ClinGen gnomAD
TCGA novel	308	T>I	Variant assessed as Somatic; impact. [NCI-TCGA]	No	NCI-TCGA
rs1185110865 CA366006860	309	A>G		No	ClinGen gnomAD
CA149921949 rs924370563	309	A>T		No	ClinGen TOPMed gnomAD
rs778803132 CA149921950	310	I>L		No	ClinGen ExAC TOPMed gnomAD
CA4042858 rs778803132	310	I>V		No	ClinGen ExAC TOPMed gnomAD
rs752532394 CA4042860	311	N>D		No	ClinGen ExAC gnomAD
CA366006880 rs1460769841	311	N>S		No	ClinGen TOPMed
rs1379795000 CA366006895	313	Y>C		No	ClinGen TOPMed
CA366006891 rs1273492020	313	Y>H		No	ClinGen gnomAD
CA366006918 rs1419449209	317	P>S		No	ClinGen gnomAD
rs777766635 CA4042863	322	E>V		No	ClinGen ExAC gnomAD
CA366006978 rs1433095113	325	E>G		No	ClinGen gnomAD
CA366007003 rs1433413325	328	T>I		No	ClinGen TOPMed
CA4042866 rs781439058	330	I>F		No	ClinGen ExAC gnomAD
rs1562274537 CA366007015	330	I>T		No	ClinGen Ensembl

No associated diseases with Q9NU53

4 regional properties for Q9NU53

Type	Name	Position	InterPro Accession
domain	Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)	240 - 415	IPR002314
domain	Aminoacyl-tRNA synthetase, class II	177 - 425	IPR006195
domain	Serine-tRNA synthetase, type1, N-terminal	1 - 110	IPR015866
domain	Serine-tRNA ligase catalytic core domain	123 - 432	IPR033729

Functions

		Description
EC Number
Subcellular Localization	Membrane ; Single-pass type I membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

1 GO annotations of cellular component

Name	Definition
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

No GO annotations of molecular function

Name	Definition
No GO annotations for molecular function

No GO annotations of biological process

Name	Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins

10	20	30	40	50	60
MEGAPPGSLA	LRLLLFVALP	ASGWLTTGAP	EPPPLSGAPQ	DGIRINVTTL	KDDGDISKQQ
70	80	90	100	110	120
VVLNITYESG	QVYVNDLPVN	SGVTRISCQT	LIVKNENLEN	LEEKEYFGIV	SVRILVHEWP
130	140	150	160	170	180
MTSGSSLQLI	VIQEEVVEID	GKQVQQKDVT	EIDILVKNRG	VLRHSNYTLP	LEESMLYSIS
190	200	210	220	230	240
RDSDILFTLP	NLSKKESVSS	LQTTSQYLIR	NVETTVDEDV	LPGKLPETPL	RAEPPSSYKV
250	260	270	280	290	300
MCQWMEKFRK	DLCRFWSNVF	PVFFQFLNIM	VVGITGAAVV	ITILKVFFPV	SEYKGILQLD
310	320
KVDVIPVTAI	NLYPDGPEKR	AENLEDKTCI