Q9N2D3

PR
Gene name
PGC
Protein name
Gastricsin
Names
Pepsinogen C
Species
Callithrix jacchus (White-tufted-ear marmoset)
KEGG Pathway
cjc:100404738
EC number
3.4.23.3: Aspartic endopeptidases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

3-85 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9N2D3

Entry ID Method Resolution Chain Position Source
AF-Q9N2D3-F1 Predicted AlphaFoldDB

No variants for Q9N2D3

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9N2D3

No associated diseases with Q9N2D3

2 regional properties for Q9N2D3

Type Name Position InterPro Accession
domain Band 7 domain 23 - 196 IPR001107
conserved_site Band 7/stomatin-like, conserved site 136 - 164 IPR018080

Functions

Description
EC Number 3.4.23.3 Aspartic endopeptidases
Subcellular Localization
  • Secreted
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
extracellular region The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.

1 GO annotations of molecular function

Name Definition
aspartic-type endopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.

2 GO annotations of biological process

Name Definition
digestion The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
proteolysis The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKWMVVAFIC LQLLEATVVK VPLKKFKSIR ETMKEKGLLW EFLKTHKHDP ARKYRVSDLS
70 80 90 100 110 120
VSYEPMDYMD AAYFGEISIG TPPQNFLVLF DTGSSNLWVP SVYCQSQACT SHSRFNPSAS
130 140 150 160 170 180
STYSSNGQTF SLQYGSGSLT GFFGYDTLTV QSIQVPNQEF GLSENEPGTN FVYAQFDGIM
190 200 210 220 230 240
GLAYPALSMG GATTAMQGML QEGALTSPVF SFYLSNQQGS SGGAVIFGGV DSSLYTGQIY
250 260 270 280 290 300
WAPVTQELYW QIGIEEFLIG GQASGWCSEG CQAIVDTGTS LLTVPQQYMS AFLEATGAQE
310 320 330 340 350 360
DEYGQFLVNC DSIQNLPTLT FIINGVEFPL PPSSYILSNN GYCTVGVEPT YLSSQNSQPL
370 380
WILGDVFLRS YYSVFDLGNN RVGFATAA