Q9M2I2

PR
Gene name
At3g58340 (F9D24.250)
Protein name
MATH domain and coiled-coil domain-containing protein At3g58340
Names
RTM3-like protein At3g58340
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT3G58340
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

116-213 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9M2I2

Entry ID Method Resolution Chain Position Source
AF-Q9M2I2-F1 Predicted AlphaFoldDB

52 variants for Q9M2I2

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_3_21590385_T_C 6 D>G No 1000Genomes
ENSVATH06337817 6 D>N No 1000Genomes
ENSVATH02521264 19 L>F No 1000Genomes
ENSVATH02521265 19 L>M No 1000Genomes
tmp_3_21590200_A_C 38 L>R No 1000Genomes
tmp_3_21590194_G_A 40 A>V No 1000Genomes
tmp_3_21590156_A_T 53 Y>N No 1000Genomes
ENSVATH02521261 59 F>L No 1000Genomes
tmp_3_21590096_G_A 73 R>C No 1000Genomes
ENSVATH00425955 75 C>S No 1000Genomes
ENSVATH00425954 83 E>* No 1000Genomes
ENSVATH06337811 104 E>K No 1000Genomes
tmp_3_21589816_C_T 111 E>K No 1000Genomes
ENSVATH06337810 116 D>A No 1000Genomes
ENSVATH06337809 124 Q>K No 1000Genomes
tmp_3_21589732_T_A 139 T>S No 1000Genomes
tmp_3_21589687_T_C 154 N>D No 1000Genomes
ENSVATH08160507 155 K>T No 1000Genomes
tmp_3_21589680_G_C 156 T>S No 1000Genomes
tmp_3_21589663_G_A 162 Q>* No 1000Genomes
ENSVATH02521247 166 I>S No 1000Genomes
ENSVATH02521245 169 P>S No 1000Genomes
tmp_3_21589569_T_G 193 Q>P No 1000Genomes
ENSVATH06337804 203 R>G No 1000Genomes
ENSVATH06337803 203 R>K No 1000Genomes
ENSVATH12818774 206 F>L No 1000Genomes
ENSVATH06337802 208 K>* No 1000Genomes
ENSVATH12818773 208 K>N No 1000Genomes
tmp_3_21589421_G_T 210 P>T No 1000Genomes
ENSVATH06337801 211 D>E No 1000Genomes
ENSVATH14450796 213 A>V No 1000Genomes
ENSVATH02521239 214 V>I No 1000Genomes
ENSVATH06337800 226 T>A No 1000Genomes
ENSVATH00425948 229 N>S No 1000Genomes
ENSVATH02521238 234 V>A No 1000Genomes
ENSVATH00425947 234 V>I No 1000Genomes
ENSVATH02521237 237 T>M No 1000Genomes
ENSVATH12818772 250 L>R No 1000Genomes
tmp_3_21589274_A_G 259 Y>H No 1000Genomes
ENSVATH06337799 260 L>V No 1000Genomes
ENSVATH12818770 266 K>N No 1000Genomes
tmp_3_21589249_A_G 267 V>A No 1000Genomes
tmp_3_21589223_G_T 276 H>N No 1000Genomes
tmp_3_21589219_A_G 277 V>A No 1000Genomes
tmp_3_21589220_C_A 277 V>L No 1000Genomes
ENSVATH06337798 281 K>N No 1000Genomes
tmp_3_21589186_A_C 288 L>W No 1000Genomes
tmp_3_21589184_T_C 289 I>V No 1000Genomes
tmp_3_21589158_T_A 297 Q>H No 1000Genomes
ENSVATH00425944 307 K>E No 1000Genomes
tmp_3_21589123_T_C 309 K>R No 1000Genomes
ENSVATH00425943 317 A>D No 1000Genomes

No associated diseases with Q9M2I2

8 regional properties for Q9M2I2

Type Name Position InterPro Accession
domain EF-hand domain 316 - 351 IPR002048
domain GTP binding domain 430 - 522 IPR006073
domain Mitochondrial Rho GTPase 1/3, EF hand associated, type-1 353 - 421 IPR013566
domain EF hand associated, type-2 230 - 315 IPR013567
binding_site EF-Hand 1, calcium-binding site 208 - 220 IPR018247-1
binding_site EF-Hand 1, calcium-binding site 329 - 341 IPR018247-2
domain MIRO domain 12 - 179 IPR020860-1
domain MIRO domain 425 - 599 IPR020860-2

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

15 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q6IQ16 SPOPL Speckle-type POZ protein-like Homo sapiens (Human) PR
Q6YCH2 Tdpoz4 TD and POZ domain-containing protein 4 Mus musculus (Mouse) PR
Q2M2N2 Spopl Speckle-type POZ protein-like Mus musculus (Mouse) PR
P34371 bath-42 BTB and MATH domain-containing protein 42 Caenorhabditis elegans PR
F4IN32 At2g42460 MATH domain and coiled-coil domain-containing protein At2g42460 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A0 At3g44790 MATH domain and coiled-coil domain-containing protein At3g44790 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4A1 At3g44800 MATH domain and coiled-coil domain-containing protein At3g44800 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG7 At2g42480 MATH domain and coiled-coil domain-containing protein At2g42480 Arabidopsis thaliana (Mouse-ear cress) PR
Q9LSD2 At3g27040 MATH domain and coiled-coil domain-containing protein At3g27040 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J0 At3g58260 MATH domain and coiled-coil domain-containing protein At3g58260 Arabidopsis thaliana (Mouse-ear cress) PR
Q9M2J5 At3g58210 MATH domain and coiled-coil domain-containing protein At3g58210 Arabidopsis thaliana (Mouse-ear cress) PR
Q9ZUA7 At2g01790 MATH domain and coiled-coil domain-containing protein At2g01790 Arabidopsis thaliana (Mouse-ear cress) PR
P0DKG4 At2g42465 MATH domain and coiled-coil domain-containing protein At2g42465 Arabidopsis thaliana (Mouse-ear cress) PR
Q9SHT3 At2g05410 MATH domain and coiled-coil domain-containing protein At2g05410 Arabidopsis thaliana (Mouse-ear cress) PR
F4J4P8 At3g58220 MATH domain and coiled-coil domain-containing protein At3g58220 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MAKAVDKKFC WEIKNFSSLN SERCHSVPVV IGDCKWRLVA FPKGYKADYL SLYLEVADFK
70 80 90 100 110 120
SLPSGWRRYV KFRACIVNQL SQELSVQQET QRWFDQNAPG WGFENMLLLT ELNAKDGGFL
130 140 150 160 170 180
VNGQVMIVAE VEFLEVIGTL DESEEIIKSS DLINKTQEVA QQVKEIIQPN DLINKTQEVA
190 200 210 220 230 240
QQVKESIDVN GFQVLPSQVE SVRRIFKKHP DIAVGFQVKN QHLRKTFMNF LVNVIETMCQ
250 260 270 280 290 300
SLQELSNEDL VEVDIALTYL KDAGFKVDWL EKKLDHVKEK KEKEQSGLII LQGIEQQLHE
310 320
LMHKCEKKKS EVLSVGAPLK FDDVV