Q9LXX6
PR
Gene name |
SEC15A (At3g56640, T5P19.290) |
Protein name |
Exocyst complex component SEC15A |
Names |
AtSec15a, Probable exocyst complex component 6 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT3G56640 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LXX6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LXX6-F1 | Predicted | AlphaFoldDB |
58 variants for Q9LXX6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| ENSVATH06327449 | 30 | G>D | No | 1000Genomes | |
| tmp_3_20982055_A_G | 31 | D>G | No | 1000Genomes | |
| ENSVATH06327450 | 45 | R>G | No | 1000Genomes | |
| ENSVATH02514603 | 51 | H>N | No | 1000Genomes | |
| ENSVATH06327451 | 54 | K>R | No | 1000Genomes | |
| tmp_3_20982228_G_T | 89 | A>S | No | 1000Genomes | |
| ENSVATH00422921 | 101 | F>I | No | 1000Genomes | |
| ENSVATH06327454 | 101 | F>L | No | 1000Genomes | |
| tmp_3_20982318_G_A | 119 | E>K | No | 1000Genomes | |
| ENSVATH06327458 | 121 | Y>S | No | 1000Genomes | |
| tmp_3_20982409_G_A | 149 | S>N | No | 1000Genomes | |
| tmp_3_20982417_T_A | 152 | S>T | No | 1000Genomes | |
| tmp_3_20982487_C_G | 175 | P>R | No | 1000Genomes | |
| ENSVATH12795151 | 188 | P>S | No | 1000Genomes | |
| tmp_3_20982673_G_T | 237 | R>L | No | 1000Genomes | |
| ENSVATH06327467 | 246 | T>A | No | 1000Genomes | |
| tmp_3_20982748_A_G | 262 | E>G | No | 1000Genomes | |
| tmp_3_20982778_C_T | 272 | T>I | No | 1000Genomes | |
| tmp_3_20982807_A_T | 282 | T>S | No | 1000Genomes | |
| tmp_3_20982823_C_G | 287 | P>R | No | 1000Genomes | |
| ENSVATH00422922 | 309 | T>S | No | 1000Genomes | |
| ENSVATH14444260 | 326 | A>V | No | 1000Genomes | |
| tmp_3_20982964_G_A | 334 | R>Q | No | 1000Genomes | |
| ENSVATH06327471 | 355 | A>T | No | 1000Genomes | |
| tmp_3_20983045_C_G | 361 | A>G | No | 1000Genomes | |
| ENSVATH12795195 | 362 | I>L | No | 1000Genomes | |
| ENSVATH12795196 | 367 | F>Y | No | 1000Genomes | |
| ENSVATH12795197 | 369 | R>I | No | 1000Genomes | |
| tmp_3_20983084_C_T | 374 | T>I | No | 1000Genomes | |
| ENSVATH06327474 | 405 | D>G | No | 1000Genomes | |
| ENSVATH06327477 | 425 | T>I | No | 1000Genomes | |
| ENSVATH06327476 | 425 | T>S | No | 1000Genomes | |
| ENSVATH06327478 | 428 | T>A | No | 1000Genomes | |
| tmp_3_20983253_C_A | 430 | D>E | No | 1000Genomes | |
| ENSVATH06327479 | 441 | A>T | No | 1000Genomes | |
| ENSVATH06327480 | 455 | S>A | No | 1000Genomes | |
| ENSVATH12795200 | 465 | A>T | No | 1000Genomes | |
| tmp_3_20983357_C_T | 465 | A>V | No | 1000Genomes | |
| tmp_3_20983359_C_T | 466 | P>S | No | 1000Genomes | |
| tmp_3_20983468_G_A | 502 | R>K | No | 1000Genomes | |
| tmp_3_20983500_T_G | 513 | L>V | No | 1000Genomes | |
| ENSVATH00422925 | 534 | I>T | No | 1000Genomes | |
| tmp_3_20983577_A_G | 538 | I>M | No | 1000Genomes | |
| ENSVATH12795202 | 550 | R>Q | No | 1000Genomes | |
| tmp_3_20983663_A_T | 567 | Q>L | No | 1000Genomes | |
| tmp_3_20983724_G_T | 587 | L>F | No | 1000Genomes | |
| tmp_3_20983731_G_C | 590 | V>L | No | 1000Genomes | |
| tmp_3_20983744_A_T | 594 | K>M | No | 1000Genomes | |
| ENSVATH12795203 | 608 | T>A | No | 1000Genomes | |
| ENSVATH00422926 | 637 | I>V | No | 1000Genomes | |
| tmp_3_20983917_G_A | 652 | E>K | No | 1000Genomes | |
| tmp_3_20983925_C_G | 654 | I>M | No | 1000Genomes | |
| tmp_3_20983942_C_T | 660 | S>F | No | 1000Genomes | |
| ENSVATH00422927 | 661 | T>I | Number of days following stratification to opening of first flower. the experiment was stopped at 200 d and accessions that had not flowered at that point were assigned a value of 200 [18c with 16 hrs daylight and vernalized (5 wks at 4c)] [EnsemblGenome] | No | 1000Genomes |
| ENSVATH00422928 | 681 | D>N | No | 1000Genomes | |
| ENSVATH12795204 | 740 | N>S | No | 1000Genomes | |
| ENSVATH12795235 | 774 | A>V | No | 1000Genomes | |
| tmp_3_20984329_T_A | 789 | F>Y | No | 1000Genomes |
No associated diseases with Q9LXX6
1 regional properties for Q9LXX6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Exocyst complex subunit Sec15, C-terminal | 443 - 754 | IPR046361 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| exocyst | A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
7 GO annotations of biological process
| Name | Definition |
|---|---|
| acceptance of pollen | The recognition and acceptance of pollen by cells in the stigma, mediated by the sharing and interaction of the single locus incompatibility haplotypes. |
| exocytosis | A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. |
| Golgi to plasma membrane transport | The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. |
| intracellular protein transport | The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. |
| pollen germination | The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture. |
| pollen tube growth | Growth of pollen via tip extension of the intine wall. |
| vesicle tethering involved in exocytosis | The initial, indirect interaction between a secretory vesicle membrane and a site of exocytosis in the plasma membrane. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to docking and fusion. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MMEAKPKRRI | VTENGDTGED | LVLATLIGNG | DDVGPLVRHA | FEMGRPEPLV | HQLKNVARKK |
| 70 | 80 | 90 | 100 | 110 | 120 |
| EAEIEDLCKT | HYEEFIVAVD | ELRGVLVDAE | ELKSDLASDN | FRLQEVGSAL | LVKLEELLES |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YAVKKNVTEA | IKMSKICVQA | LELCVKCNSY | ISEGQFYHAL | KTMDLIEKSY | LKLIPLKVLK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LVIERRIPVI | KTHIEKKVCS | QFNEWLVHIR | SSSKNIGQTA | IGLTASARQR | EEEMLERQRR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AEEQNTGGLG | ELAYTLDVED | SEQDSVLKFD | LTPLYRAYHI | HTILGVPERF | RDYYYENRLL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| QLQSDLQITY | TQPFVESYQT | FLAQVAGYFI | VEDRVIRTAG | DFLLADQVET | MWETAISKIV |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AILENQFARM | DSPTHLLLVK | DYVTLLGTTL | RQYGYEVGPV | LDALDKSRDK | YHELLLEECR |
| 430 | 440 | 450 | 460 | 470 | 480 |
| KQIVTAITED | TYQQMVIKKE | ADYENNVLSF | NLQTSDIMPA | FTYIAPFSSM | VPDVCRIIRS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| YIKGSVDYLS | YGVNTNFFSV | LRKYLDKILI | DVLNEVILET | ISNNSIGVSQ | AMQIAANISF |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LEKASDYFLR | HAAQLCGIPS | RSVERPQASL | AAKVVLKTSR | DAAYLALLNV | VNTKLDEFMK |
| 610 | 620 | 630 | 640 | 650 | 660 |
| LTENVNWTTE | EMPQGPHEYI | NEVVIYLETV | MSTAQQILPM | DALYKVGVGA | IEHISNSIVS |
| 670 | 680 | 690 | 700 | 710 | 720 |
| TFLSDSIKRF | NANAVSAINH | DLRVIENFAD | ERYHSSGLNE | IYKEGSFRSY | LVEARQLINL |
| 730 | 740 | 750 | 760 | 770 | 780 |
| LSSSQPENFM | NPVIRERNYN | TLDYKKVATI | CEKFKDSADG | IFGSLANRNT | KLTAKKKSMD |
| MLKKRLKEFN |