Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q9LTX4

Entry ID Method Resolution Chain Position Source
AF-Q9LTX4-F1 Predicted AlphaFoldDB

40 variants for Q9LTX4

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH12674725 22 S>T No 1000Genomes
ENSVATH12674694 23 Y>N No 1000Genomes
ENSVATH14620368 41 T>I No 1000Genomes
ENSVATH12674693 46 G>C No 1000Genomes
tmp_5_20327527_G_C 54 T>R No 1000Genomes
tmp_5_20327504_G_T 62 P>T No 1000Genomes
ENSVATH03402192 68 Q>R No 1000Genomes
ENSVATH07386281 83 L>F No 1000Genomes
tmp_5_20327434_T_C 85 H>R No 1000Genomes
ENSVATH00723734 100 F>Y No 1000Genomes
ENSVATH00723732 143 I>V No 1000Genomes
tmp_5_20327075_A_T 147 L>I No 1000Genomes
tmp_5_20327045_C_T 157 D>N No 1000Genomes
ENSVATH03402189 158 L>I No 1000Genomes
ENSVATH07386273 164 L>I No 1000Genomes
tmp_5_20326906_G_T 203 A>E No 1000Genomes
tmp_5_20326877_A_C 213 L>V No 1000Genomes
ENSVATH07386270 261 L>W No 1000Genomes
ENSVATH12674692 344 L>V No 1000Genomes
tmp_5_20326393_G_A 348 S>L No 1000Genomes
tmp_5_20326246_C_T 372 A>T No 1000Genomes
ENSVATH12674690 377 G>R No 1000Genomes
tmp_5_20325986_T_C 430 T>A No 1000Genomes
ENSVATH00723723 528 A>T No 1000Genomes
ENSVATH03402181 543 M>I No 1000Genomes
ENSVATH07386253 590 R>T No 1000Genomes
ENSVATH12674667 592 K>R No 1000Genomes
tmp_5_20325181_T_A 593 K>M No 1000Genomes
tmp_5_20325166_C_T 598 G>E No 1000Genomes
tmp_5_20324963_A_C 635 I>S No 1000Genomes
tmp_5_20324961_G_A 636 L>F No 1000Genomes
tmp_5_20324713_G_C 672 A>G No 1000Genomes
ENSVATH00723708 672 A>S No 1000Genomes
ENSVATH00723707 676 A>V No 1000Genomes
ENSVATH12674613 774 Y>H No 1000Genomes
ENSVATH07386249 775 D>N No 1000Genomes
ENSVATH00723701 786 I>V No 1000Genomes
ENSVATH07386248 803 T>I No 1000Genomes
ENSVATH12674611 808 L>V No 1000Genomes
tmp_5_20324206_A_T 814 D>E No 1000Genomes

No associated diseases with Q9LTX4

7 regional properties for Q9LTX4

Type Name Position InterPro Accession
domain DNA topoisomerase, type IA, domain 2 146 - 242 IPR003601
domain DNA topoisomerase, type IA, DNA-binding domain 289 - 545 IPR003602
domain TOPRIM domain 3 - 155 IPR006171
domain DNA topoisomerase, type IA, central 112 - 125 IPR013497-1
domain DNA topoisomerase, type IA, central 170 - 593 IPR013497-2
active_site DNA topoisomerase, type IA, active site 326 - 340 IPR023406
domain DNA topoisomerase 3-like, TOPRIM domain 3 - 167 IPR034144

Functions

Description
EC Number
Subcellular Localization
  • Nucleus membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
nuclear membrane Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
ion transport The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5N941 Os01g0870100 Probable ion channel POLLUX Oryza sativa subsp japonica (Rice) PR
Q8VZM7 At5g02940 Putative ion channel POLLUX-like 1 Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MPIHTPRRTS LFQRSKTLPT NSYRRFTSPV IPTFRYDDGD TVSYDGDDSS NLPTVPNPEE
70 80 90 100 110 120
KPVPVPSQSP SQRITRLWTQ FSLTHCLKFI CSCSFTYVMF LRSKVSRLEA ENIILLTRCN
130 140 150 160 170 180
SSSDNNEMEE TNSRAVVFFS VIITFVLPFL LYMYLDDLSH VKNLLRRTNQ KKEDVPLKKR
190 200 210 220 230 240
LAYSLDVCFS VYPYAKLLAL LLATVVLIVY GGLALYAVSD CGVDEALWLS WTFVADSGSH
250 260 270 280 290 300
ADRVGVGARI VSVAISAGGM LIFATMLGLI SDAISKMVDS LRKGKSEVLE SNHILILGWS
310 320 330 340 350 360
DKLGSLLKQL AIANKSIGGG VVVVLAERDK EEMETDIAKF EFDLMGTSVI CRSGSPLILA
370 380 390 400 410 420
DLKKVSVSNA RAIIVLGSDE NADQSDARAL RVVLSLTGVK EGWKGHVVVE MCDLDNEPLV
430 440 450 460 470 480
KLVGGERIET VVAHDVIGRL MIQCALQPGL AQIWEDILGF ENAEFYIKKW PQLDGYCFED
490 500 510 520 530 540
VLISFPNAIP CGVKVAADGK IVLNPSDDYV LKEGDEILVI AEDDDTYAPG SLPEVRMCHF
550 560 570 580 590 600
PKMQDPPKYP EKILFCGWRR DIDDMIKVLE ALLAPGSELW MFNEVPDQER EKKLTDAGLN
610 620 630 640 650 660
ISKLVNIKLV HRQGNAVIRR HLESLPLETF DSILILAEQS LENSIVHSDS RSLATLLLIR
670 680 690 700 710 720
DIQSKRLPYK DAKSSALRIS GFPNCCWIRK MQQASDKSIV ISEILDSRTK NLVSVSRISD
730 740 750 760 770 780
YVLSNELVSM ALAMVAEDKQ INRVLKELFA EKGNELCIRP AEFYIYDQEE VCFYDIMRRA
790 800 810 820
RQRQEIIIGY RLAGMEQAVI NPTDKSKLTK WSLDDVFVVI ASSQ