Q9LQU5

PR
Gene name
NUDT18 (NUDX18, At1g14860, F10B6.26)
Protein name
Nudix hydrolase 18, mitochondrial
Names
AtNUDT18
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G14860
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-43 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LQU5

Entry ID Method Resolution Chain Position Source
AF-Q9LQU5-F1 Predicted AlphaFoldDB

12 variants for Q9LQU5

Variant ID(s) Position Change Description Diseaes Association Provenance
ENSVATH13898699 26 I>L No 1000Genomes
ENSVATH13898700 38 I>T No 1000Genomes
tmp_1_5125225_C_A 53 H>Q No 1000Genomes
ENSVATH13898701 66 E>D No 1000Genomes
tmp_1_5125556_T_A 94 D>E No 1000Genomes
ENSVATH00023945 107 F>L No 1000Genomes
ENSVATH04578488 117 L>V No 1000Genomes
ENSVATH04578489 138 D>E No 1000Genomes
ENSVATH04578492 156 L>F No 1000Genomes
tmp_1_5125761_C_T 163 P>S No 1000Genomes
ENSVATH04578493 168 E>K No 1000Genomes
tmp_1_5125800_T_G 176 Y>D No 1000Genomes

No associated diseases with Q9LQU5

3 regional properties for Q9LQU5

Type Name Position InterPro Accession
domain NUDIX hydrolase domain 18 - 153 IPR000086
conserved_site NUDIX hydrolase, conserved site 60 - 81 IPR020084
domain Diphosphoinositol polyphosphate phosphohydrolase-like, NUDIX domain 21 - 146 IPR047198

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

2 GO annotations of molecular function

Name Definition
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
metal ion binding Binding to a metal ion.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9ZU95 NUDT17 Nudix hydrolase 17, mitochondrial Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MVCLVSRTGR QSQRYNKGRR QVVGCIPYRL KISSDGTISD EFEVLVISSQ KGHALMFPKG
70 80 90 100 110 120
GWELDESVEE AASRESLEEA GVVGNVERQL GKWDFLSKSK GTFYEGFMFP MLVKEELELW
130 140 150 160 170
PEQHLRQRIW MKVDEARDAC RDWWMKEALD VLVQRLSLLS LKPMEEDENL PLISIY