Q9LPM2
Gene name |
At1g49990 (F2J10.12) |
Protein name |
F-box protein At1g49990 |
Names |
|
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT1G49990 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9LPM2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LPM2-F1 | Predicted | AlphaFoldDB |
70 variants for Q9LPM2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_1_18513715_G_C | 7 | R>T | No | 1000Genomes | |
| ENSVATH13473169 | 10 | P>S | No | 1000Genomes | |
| ENSVATH04920039 | 24 | A>V | No | 1000Genomes | |
| ENSVATH13473170 | 36 | V>A | No | 1000Genomes | |
| ENSVATH13473170 | 36 | V>E | No | 1000Genomes | |
| tmp_1_18513817_A_G | 41 | Y>C | No | 1000Genomes | |
| ENSVATH04920041 | 45 | L>P | No | 1000Genomes | |
| ENSVATH00090624 | 52 | S>N | No | 1000Genomes | |
| tmp_1_18513895_G_A | 67 | R>H | No | 1000Genomes | |
| tmp_1_18513923_T_A | 76 | H>Q | No | 1000Genomes | |
| tmp_1_18513928_G_A | 78 | C>Y | No | 1000Genomes | |
| ENSVATH01332937 | 86 | S>T | No | 1000Genomes | |
| tmp_1_18513957_G_T | 88 | V>F | No | 1000Genomes | |
| ENSVATH13473172 | 94 | F>L | No | 1000Genomes | |
| tmp_1_18514012_A_G | 106 | Y>C | No | 1000Genomes | |
| ENSVATH00090626 | 120 | L>F | No | 1000Genomes | |
| ENSVATH04920044 | 131 | Y>* | No | 1000Genomes | |
| tmp_1_18514087_A_C | 131 | Y>S | No | 1000Genomes | |
| tmp_1_18514097_C_A | 134 | F>L | No | 1000Genomes | |
| ENSVATH01332939 | 147 | P>S | No | 1000Genomes | |
| ENSVATH00090627 | 152 | P>S | No | 1000Genomes | |
| ENSVATH04920045 | 159 | P>S | No | 1000Genomes | |
| tmp_1_18514189_A_G | 165 | Y>C | No | 1000Genomes | |
| tmp_1_18514192_G_A | 166 | S>N | No | 1000Genomes | |
| ENSVATH00090628 | 174 | V>I | No | 1000Genomes | |
| tmp_1_18514228_T_G | 178 | V>G | No | 1000Genomes | |
| tmp_1_18514231_T_A | 179 | V>D | No | 1000Genomes | |
| tmp_1_18514230_G_A,GA | 179 | V>I | No | 1000Genomes | |
| ENSVATH00090629 | 194 | D>N | No | 1000Genomes | |
| ENSVATH04920048 | 200 | M>I | No | 1000Genomes | |
| ENSVATH04920049 | 201 | Y>C | No | 1000Genomes | |
| ENSVATH04920049 | 201 | Y>F | No | 1000Genomes | |
| tmp_1_18514371_G_A | 226 | V>I | No | 1000Genomes | |
| ENSVATH04920051 | 239 | G>E | No | 1000Genomes | |
| ENSVATH04920052 | 241 | L>F | No | 1000Genomes | |
| ENSVATH01332940 | 243 | M>L | No | 1000Genomes | |
| ENSVATH01332941 | 248 | M>L | No | 1000Genomes | |
| tmp_1_18514471_A_G | 259 | H>R | No | 1000Genomes | |
| tmp_1_18514503_G_A | 270 | V>I | No | 1000Genomes | |
| tmp_1_18514506_AT_TT,A | 271 | I>L | No | 1000Genomes | |
| tmp_1_18514509_C_A | 272 | P>T | No | 1000Genomes | |
| ENSVATH04920053 | 276 | A>V | No | 1000Genomes | |
| tmp_1_18514559_T_A | 288 | H>Q | No | 1000Genomes | |
| ENSVATH04920055 | 292 | R>W | No | 1000Genomes | |
| ENSVATH13473206 | 300 | E>D | No | 1000Genomes | |
| ENSVATH13473207 | 318 | H>Q | No | 1000Genomes | |
| ENSVATH01332942 | 320 | K>E | No | 1000Genomes | |
| tmp_1_18514655_A_C | 320 | K>N | No | 1000Genomes | |
| ENSVATH00090630 | 321 | E>K | No | 1000Genomes | |
| tmp_1_18514681_G_C | 329 | W>S | No | 1000Genomes | |
| ENSVATH04920057 | 330 | E>K | No | 1000Genomes | |
| ENSVATH14274821 | 333 | M>I | No | 1000Genomes | |
| tmp_1_18514708_C_G | 338 | S>C | No | 1000Genomes | |
| ENSVATH04920059 | 345 | L>M | No | 1000Genomes | |
| tmp_1_18514749_A_C | 352 | T>P | No | 1000Genomes | |
| ENSVATH01332943 | 353 | Y>D | No | 1000Genomes | |
| tmp_1_18514773_C_T | 360 | R>C | No | 1000Genomes | |
| ENSVATH04920060 | 360 | R>P | No | 1000Genomes | |
| ENSVATH04920061 | 369 | Y>S | No | 1000Genomes | |
| tmp_1_18514806_C_G | 371 | Q>E | No | 1000Genomes | |
| ENSVATH01332946 | 383 | N>D | No | 1000Genomes | |
| tmp_1_18514844_T_G | 383 | N>K | No | 1000Genomes | |
| ENSVATH00090631 | 396 | T>K | No | 1000Genomes | |
| ENSVATH00090631 | 396 | T>M | No | 1000Genomes | |
| tmp_1_18514904_G_A | 403 | M>I | No | 1000Genomes | |
| tmp_1_18514910_G_C | 405 | E>D | No | 1000Genomes | |
| ENSVATH04920063 | 409 | G>A | No | 1000Genomes | |
| tmp_1_18514945_T_G | 417 | V>G | No | 1000Genomes | |
| ENSVATH13473210 | 427 | R>Q | No | 1000Genomes | |
| tmp_1_18514977_C_T | 428 | P>S | No | 1000Genomes |
No associated diseases with Q9LPM2
1 regional properties for Q9LPM2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | F-box domain | 13 - 43 | IPR001810 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| ubiquitin-protein transferase activity | Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome. |
1 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q9LFV5 | At5g15710 | F-box/kelch-repeat protein At5g15710 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| 10 | 20 | 30 | 40 | 50 | 60 |
| METGRRRTIP | EVEILARLPL | RSIARFKSVC | KRWKSVIESD | YFRRLFGSFH | RSSSTSWSIM |
| 70 | 80 | 90 | 100 | 110 | 120 |
| FRTEYLREMT | QAIGFHGCKT | WDLPKSLVSY | IMPFQEYPNL | PTSEYYYIAS | SNGLIWIDVL |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSRIKNKVYS | YKSFVGNPVL | QEWVEIPQPP | NPWVQDKHPW | YPSPYSGVGM | VTRVENGVVS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SFKMVRTVQM | ELIDRRDEGM | YLWRVCVYSS | ETGLWTFKQV | FSSRPVHGGR | VDSPVNLNGV |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LYMWDRYMFS | NGPGVLVAHD | FYGADDQCQV | IPLPGANDEH | EHEHDDEHEH | VRRCLTTSGE |
| 310 | 320 | 330 | 340 | 350 | 360 |
| DVIFIEVIHR | ILKAWRLHNK | ESERWQLIWE | VVMPSFISDV | NCFPLAMNPF | DTYIVYLWDR |
| 370 | 380 | 390 | 400 | 410 | 420 |
| QHGCLVSGYL | QAQEFIVHQE | SENGSSSEGD | CCRVNTSGTE | GYMEERCDGV | LMLSQFVLPS |
| WMDSVPRPPN |