AiPD: Autoinhibited Protein Database

Gene name	CSLC4
Protein name	Xyloglucan glycosyltransferase 4
Names	Cellulose synthase-like protein C4, AtCslC4, Xyloglucan synthase 4
Species	Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway	ath:AT3G28180
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

1-116 (Predicted disordered autoinhibitory region) PR

1-116 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q9LJP4-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
tmp_3_10506141_A_T	11	E>V	No	1000Genomes
tmp_3_10506151_C_A	14	D>E	No	1000Genomes
ENSVATH11108168	33	R>H	No	1000Genomes
ENSVATH00358505	52	L>V	No	1000Genomes
ENSVATH02230036	53	I>V	No	1000Genomes
tmp_3_10506340_A_C	77	E>D	No	1000Genomes
ENSVATH14045578	81	K>R	No	1000Genomes
ENSVATH05947092	110	F>Y	No	1000Genomes
ENSVATH02230039	134	M>L	No	1000Genomes
ENSVATH11108170	172	G>C	No	1000Genomes
tmp_3_10506644_A_C	179	K>Q	No	1000Genomes
ENSVATH14045580	183	P>A	No	1000Genomes
ENSVATH00358511	187	E>D	No	1000Genomes
ENSVATH07987162	188	E>K	No	1000Genomes
ENSVATH02230059	246	L>I	No	1000Genomes
tmp_3_10507024_G_C	259	G>R	No	1000Genomes
tmp_3_10507964_G_T	333	D>Y	No	1000Genomes
ENSVATH05947124	374	I>V	No	1000Genomes
tmp_3_10508286_G_A	440	R>Q	No	1000Genomes
ENSVATH14045648	593	E>K	No	1000Genomes
ENSVATH05947134	620	T>M	No	1000Genomes

Type	Name	Position	InterPro Accession
domain	Glycosyltransferase 2-like	293 - 499	IPR001173

		Description
EC Number
Subcellular Localization	Golgi apparatus membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
endosome	A vacuole to which materials ingested by endocytosis are delivered.
Golgi apparatus	A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways.
Golgi membrane	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
Golgi trans cisterna	The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.
integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
trans-Golgi network	The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.

Name	Definition
glycosyltransferase activity	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
protein homodimerization activity	Binding to an identical protein to form a homodimer.

Name	Definition
cell wall organization	A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
plant organ development	Development of a plant organ, a multi-tissue plant structure that forms a functional unit.
pollen tube development	The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
Q6AU53	CSLC9	Probable xyloglucan glycosyltransferase 9	Oryza sativa subsp japonica (Rice)	PR
Q6L538	CSLC7	Probable xyloglucan glycosyltransferase 7	Oryza sativa subsp japonica (Rice)	PR
Q7PC69	CSLC3	Probable xyloglucan glycosyltransferase 3	Oryza sativa subsp japonica (Rice)	PR
Q69L19	CSLC2	Probable xyloglucan glycosyltransferase 2	Oryza sativa subsp japonica (Rice)	PR
Q9SJA2	CSLC8	Probable xyloglucan glycosyltransferase 8	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9SRT3	CSLC6	Probable xyloglucan glycosyltransferase 6	Arabidopsis thaliana (Mouse-ear cress)	PR
Q9ZQB9	CSLC12	Probable xyloglucan glycosyltransferase 12	Arabidopsis thaliana (Mouse-ear cress)	PR