Q9LDY5

PR
Gene name
FKBP17-2 (At1g18170, T10F20.17)
Protein name
Peptidyl-prolyl cis-trans isomerase FKBP17-2, chloroplastic
Names
PPIase FKBP17-2, FK506-binding protein 17-2, AtFKBP17-2, Immunophilin FKBP17-2, Rotamase
Species
Arabidopsis thaliana (Mouse-ear cress)
KEGG Pathway
ath:AT1G18170
EC number
5.2.1.8: Cis-trans isomerases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-75 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q9LDY5

Entry ID Method Resolution Chain Position Source
AF-Q9LDY5-F1 Predicted AlphaFoldDB

19 variants for Q9LDY5

Variant ID(s) Position Change Description Diseaes Association Provenance
tmp_1_6254323_C_A 11 F>L No 1000Genomes
tmp_1_6254342_T_G 18 F>V No 1000Genomes
ENSVATH11448601 21 T>A No 1000Genomes
ENSVATH11448602 22 A>T No 1000Genomes
ENSVATH11448603 23 S>P No 1000Genomes
tmp_1_6254418_C_A 43 P>H No 1000Genomes
ENSVATH13918245 69 A>V No 1000Genomes
tmp_1_6255158_T_C 132 V>A No 1000Genomes
ENSVATH11448756 155 T>S No 1000Genomes
tmp_1_6255292_G_T 177 V>L No 1000Genomes
tmp_1_6255316_A_T 185 K>* No 1000Genomes
ENSVATH13918248 186 G>* No 1000Genomes
ENSVATH11448757 187 L>F No 1000Genomes
tmp_1_6255328_G_C 189 E>Q No 1000Genomes
ENSVATH13918249 198 M>I No 1000Genomes
tmp_1_6255416_G_A 218 G>D No 1000Genomes
ENSVATH04595476 231 A>P No 1000Genomes
ENSVATH04595477 234 E>Q No 1000Genomes
ENSVATH04595478 240 D>G No 1000Genomes

No associated diseases with Q9LDY5

1 regional properties for Q9LDY5

Type Name Position InterPro Accession
domain FKBP-type peptidyl-prolyl cis-trans isomerase domain 137 - 243 IPR001179

Functions

Description
EC Number 5.2.1.8 Cis-trans isomerases
Subcellular Localization
  • Plastid, chloroplast thylakoid lumen
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

4 GO annotations of cellular component

Name Definition
chloroplast A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
chloroplast thylakoid lumen The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.
chloroplast thylakoid membrane The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

1 GO annotations of molecular function

Name Definition
peptidyl-prolyl cis-trans isomerase activity Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).

No GO annotations of biological process

Name Definition
No GO annotations for biological process

2 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q5T1M5 FKBP15 FK506-binding protein 15 Homo sapiens (Human) PR
Q9LYR5 FKBP19 Peptidyl-prolyl cis-trans isomerase FKBP19, chloroplastic Arabidopsis thaliana (Mouse-ear cress) PR
10 20 30 40 50 60
MANLFTATAP FLSLSKPFTK TASYHQCYAS SSNPPEPESS SPPPPPPPPQ PLASQQKRKK
70 80 90 100 110 120
NVETTDWVAS SLTRRFGIGA GLAWAGFLAF GVISEQIKTR IEVSQEVANT RDVEEEKEIV
130 140 150 160 170 180
LPNGIRYYDQ RVGGGATPRA GDLVVIDLKG QVQGTGQVFV DTFGTKDKKK MKPLALVVGS
190 200 210 220 230 240
KPYSKGLCEG IDYVLRSMKA GGKRRVIVPP SLGFGVDGAE LESGLQIPPN ASLEYIVEID
RVSIAPA