Q9LDQ3
Gene name |
CRK34 |
Protein name |
Cysteine-rich receptor-like protein kinase 34 |
Names |
Cysteine-rich RLK34 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
|
EC number |
2.7.11.1: Protein-serine/threonine kinases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
487-494 (Activation loop from InterPro)
Target domain |
345-624 (Protein kinase domain) |
Relief mechanism |
|
Assay |
|
505-512 (Activation loop from InterPro)
Target domain |
345-624 (Protein kinase domain) |
Relief mechanism |
|
Assay |
|
Autoinhibited structure
Activated structure
1 structures for Q9LDQ3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9LDQ3-F1 | Predicted | AlphaFoldDB |
No variants for Q9LDQ3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9LDQ3 | |||||
No associated diseases with Q9LDQ3
5 regional properties for Q9LDQ3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Arf GTPase activating protein | 405 - 527 | IPR001164 |
| domain | Pleckstrin homology domain | 265 - 362 | IPR001849 |
| repeat | Ankyrin repeat | 588 - 671 | IPR002110-1 |
| repeat | Ankyrin repeat | 672 - 702 | IPR002110-2 |
| domain | BAR domain | 5 - 237 | IPR004148 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.11.1 | Protein-serine/threonine kinases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| protein serine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate. |
| protein serine/threonine kinase activity | Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| defense response to bacterium | Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. |
| protein phosphorylation | The process of introducing a phosphate group on to a protein. |
26 homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| Q3ZC95 | BTK | Tyrosine-protein kinase | Bos taurus (Bovine) | EV SS |
| O97799 | KIT | Mast/stem cell growth factor receptor Kit | Canis lupus familiaris (Dog) (Canis familiaris) | PR |
| Q6QNF3 | PDGFRB | Platelet-derived growth factor receptor beta | Canis lupus familiaris (Dog) (Canis familiaris) | SS |
| Q24488 | Ror | Tyrosine-protein kinase transmembrane receptor Ror | Drosophila melanogaster (Fruit fly) | SS |
| Q9V6K3 | Nrk | Tyrosine-protein kinase transmembrane receptor Ror2 | Drosophila melanogaster (Fruit fly) | SS |
| Q96S53 | TESK2 | Dual specificity testis-specific protein kinase 2 | Homo sapiens (Human) | PR |
| Q9SXB5 | At1g11303 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g11303 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9SXB8 | At1g11330 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g11330 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LPZ9 | SD113 | G-type lectin S-receptor-like serine/threonine-protein kinase SD1-13 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64783 | At1g61370 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61370 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64770 | At1g61490 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61490 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9SYA0 | At1g61500 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61500 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64793 | At1g67520 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g67520 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9LW83 | CES101 | G-type lectin S-receptor-like serine/threonine-protein kinase CES101 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O81833 | SD11 | G-type lectin S-receptor-like serine/threonine-protein kinase SD1-1 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64780 | At1g61400 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61400 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64776 | At1g61440 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61440 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9SY95 | At1g61550 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61550 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64778 | At1g61420 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61420 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64774 | At1g61460 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61460 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| O64784 | At1g61360 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g61360 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| O64782 | SD129 | G-type lectin S-receptor-like serine/threonine-protein kinase SD1-29 | Arabidopsis thaliana (Mouse-ear cress) | SS |
| Q9SXB4 | At1g11300 | G-type lectin S-receptor-like serine/threonine-protein kinase At1g11300 | Arabidopsis thaliana (Mouse-ear cress) | PR |
| Q9DE49 | pdgfra | Platelet-derived growth factor receptor alpha | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| Q8AXB3 | kdrl | Vascular endothelial growth factor receptor kdr-like | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| Q90413 | fgfr4 | Fibroblast growth factor receptor 4 | Danio rerio (Zebrafish) (Brachydanio rerio) | SS |
| 10 | 20 | 30 | 40 | 50 | 60 |
| MKLKISFLPT | FLIFLISLDS | VTAQEICFSG | FFKPNSTYDL | NRRQILSTLS | SNVTSHNGFF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NSKFGQAPNR | VFINGMCIPG | TKPETCSDCI | KGASDKISES | CPNKTDAYTW | PDCCMVRYSN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| VSFSGSLVME | PSETLYHTGD | IEDTGTNLTV | FDRIWEELML | RTITAASLSS | SNGSSFGQKY |
| 190 | 200 | 210 | 220 | 230 | 240 |
| FAAEVASLTT | FQTMYAMMQC | TPDVSSKDCE | FCLKTSVGDY | ESCCRGKQGG | AVIRPSCFVR |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WDLYPYAGAF | ENVTFPPPPP | QSLPQPPVSL | IPPPVSDRAN | TTIKGIIVAI | VVPIIVILVS |
| 310 | 320 | 330 | 340 | 350 | 360 |
| LVVLLVVCRR | KKSYKTTEVQ | ATDEITTTHS | LQFSFKTIEA | ATDKFSDSNM | IGRGGFGEVY |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RGKLSSGPEV | AVKRLSKTSG | QGAEEFKNEA | VLVSKLQHKN | LVRLLGFCLE | GEEKILVYEF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| VPNKSLDYFL | FDPAKQGELD | WTRRYNIIGG | IARGILYLHQ | DSRLTIIHRD | LKASNILLDA |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DMNPKIADFG | MARIFGVDQS | QANTRRIAGT | FGYMSPEYAM | RGHFSMKSDV | YSFGVLVLEI |
| 550 | 560 | 570 | 580 | 590 | 600 |
| ISGKKNSSFY | NIDDSGSNLV | THAWRLWRNG | SPLELVDPTI | GESYQSSEAT | RCIHIALLCV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| QEDPADRPLL | PAIIMMLTSS | TTTLHVPRAP | GFCLSGRDLE | QDGVEYTEST | SRSIPGSIND |
| ASITEFYPR |