Q9KRL3
Gene name |
VC_1624 |
Protein name |
Carboxynorspermidine synthase |
Names |
C-NSPD synthase, Carboxynorspermidine dehydrogenase, CANSDH |
Species |
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) |
KEGG Pathway |
vch:VC_1624 |
EC number |
1.5.1.43: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q9KRL3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q9KRL3-F1 | Predicted | AlphaFoldDB |
No variants for Q9KRL3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q9KRL3 | |||||
No associated diseases with Q9KRL3
4 regional properties for Q9KRL3
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Immunoglobulin/major histocompatibility complex, conserved site | 273 - 279 | IPR003006 |
| domain | Immunoglobulin C1-set | 216 - 285 | IPR003597 |
| domain | Immunoglobulin-like domain | 202 - 289 | IPR007110 |
| domain | MHC class I-like antigen recognition-like | 28 - 197 | IPR011161 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.5.1.43 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| carboxynorspermidine dehydrogenase I activity | Catalysis of the reaction: carboxynorspermidine + NADP + H2O <=> L-aspartic acid 4-semialdehyde betaine + trimethylenediaminium + NADPH + H+. |
| carboxyspermidine dehydrogenase II activity | Catalysis of the reaction: carboxyspermidine + H2O + NADP <=> L-aspartic acid 4-semialdehyde betaine + 1,4-butanediammonium + NADPH + H+. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| polyamine biosynthetic process | The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSILQIGAGG | VGWVVAHKAA | QNNDVLGDIT | IASRSIAKCE | KIIESIKGKN | NLKDSSKKLE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ARQVNADDIE | SLVKLINEVK | PDLVINAGPP | WVNVAIMEAC | YQAKVSYLDT | SVSVDLCSKG |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QQVPEAYDAQ | WAFRDKFKQA | GITAILSAGF | DPGVVSVFAA | YAAKYLFDEI | DTIDVLDINA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GDHGKKFATN | FDPETNLLEI | QGDSIYWDAG | EWKRVPCHTR | MLEFDFPKCG | KFKVYSMSHD |
| 250 | 260 | 270 | 280 | 290 | 300 |
| ELRSLKEFIP | AKRIEFWMGF | GDRYLNYFNM | MRDIGLLSPE | PLTLQDGTVV | KPLQVLKAML |
| 310 | 320 | 330 | 340 | 350 | 360 |
| PDPTSLAPGY | KGLTCIGTWV | QGKKDGKARS | VFIYNHADHE | VAYHDVEHQA | IAYTTGVPAI |
| 370 | 380 | 390 | 400 | 410 | |
| TAALQFFRGE | WAEPGVFNME | QLNPDPFLET | MPSIGLGWDV | MELEPGQPDI | QVVK |