Q9KQU8

PR
Gene name
fadR
Protein name
Fatty acid metabolism regulator protein
Names
Species
Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG Pathway
vch:VC_1900
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

128-200 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

3 structures for Q9KQU8

Entry ID Method Resolution Chain Position Source
4P9U X-ray 321 A A/B/E/F 6-277 PDB
4PDK X-ray 280 A A/B 1-279 PDB
AF-Q9KQU8-F1 Predicted AlphaFoldDB

No variants for Q9KQU8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q9KQU8

No associated diseases with Q9KQU8

2 regional properties for Q9KQU8

Type Name Position InterPro Accession
domain Transcription regulator HTH, GntR 6 - 74 IPR000524
domain FadR, C-terminal domain 72 - 274 IPR028374

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
DNA-binding transcription factor activity A transcription regulator activity that modulates transcription of gene sets via selective and non-covalent binding to a specific double-stranded genomic DNA sequence (sometimes referred to as a motif) within a cis-regulatory region. Regulatory regions include promoters (proximal and distal) and enhancers. Genes are transcriptional units, and include bacterial operons.
fatty-acyl-CoA binding Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.

3 GO annotations of biological process

Name Definition
fatty acid metabolic process The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
negative regulation of phospholipid biosynthetic process Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
regulation of fatty acid metabolic process Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVIKAKSPAG FAEKYIIESI WNGRFPPGSI LPAERELSEL IGVTRTTLRE VLQRLARDGW
70 80 90 100 110 120
LTIQHGKPTK VNQFMETSGL HILDTLMTLD AENATSIVED LLAARTNISP IFMRYAFKLN
130 140 150 160 170 180
KESAERIMIN VIESCEALVN APSWDAFIAA SPYAEKIQQH VKEDSEKDEL KRQEILIAKT
190 200 210 220 230 240
FNFYDYMLFQ RLAFHSGNQI YGLIFNGLKK LYDRVGSYYF SNPQARELAM EFYRQLLAVC
250 260 270
QSGEREHLPQ VIRQYGIASG HIWNQMKMTL PSNFTEDDC